1. Nutraceuticals The Road Ahead
V. HARIHARAN
CEO & MANAGING DIRECTOR
PHYTOTECH EXTRACTS PVT. LTD.
BENGALURU
INDIA

2. Nutraceuticals Dr. Steve De Felice
“Nutraceutical are defined as “Any substance that is food or part of food that provides Medical and/or Health benefits including prevention and treatment of disease”
Dr. Steve De Felice
“Foundation for innovation in Medicine -US in 1989”

3. Back to Nature

4. Back to the nature to back our future

5. Nutraceuticals

6. Wellness - Nutraceuticals
A healthy balance of the body & mind results in a feeling of well-being
Tiredness & stress are common problems today and Nutraceuticals address these
Nutraceuticals will help to be good always ! Good means wellness

7. Pharmaceuticals & Nutraceuticals
Pharma says “Cure first and follow diet next”, the Nutraceuticals says “Follow diet first and cure next”.
Switch lifestyle from “Eat & Act” (independently) to “Eat well & Act well” (Dependently) – Choose
Nutraceuticals is best for the country and best for the world

8. Pharmaceuticals & Nutraceuticals
According to a report by Frost & Sullivan, Indian Nutraceuticals market is projected to grow to US $4 billion in 2018 at a compound annual growth rate (CAGR) of 17%
Functional foods & beverages constitute 60% of the Indian Nutraceuticals market while rest 40% is dietary supplements

9. Laws governing DHSEA – Dietary Health Supplement & Education Act (USA)
FSMA – Food Safety Modernisation Act 2011
FOSHU- Foods for Special Health Use (Japan)
FSSAI - Food Safety Standards Authority of India
Codex regulations are on the anvil
WHO is working on the guidelines for Nutraceuticals

10. Issues Quality , Safety and Efficacy Standardization
Active compound isolation
Elaborate pharmacological testing & toxicity testing
SAR ( Structure Activity Relationship)

11. Issues Use of marker compounds Finger Printing
Use of sophisticated equipments – HPTLC
Stability Testing – Accelerated & Ambient temp
Expiry dates

12. INNOVATIONS Product and Package
The innovations should take care of Newer concepts built in to the product design focusing stability and safety of the product
Product should be delicious and palatable
Product should be customer friendly with convenience & compliance
Package should be with easy administration
Should be economical and affordable to common man

13. Focus on R&D Selecting right Nutraceutical dosage forms.
De-bitterizing the extracts and making palatable formulations.
Deeper insight of In-vitro & in-Vivo studies of the actives as well as the formulations
Conducting stability studies following ICH guidelines and conforming the shelf life of the products
Trade dress with consumer friendly packaging
Conforming to FSSAI regulations

14. Newer Products
Switch over from conventional dosage forms such as tablets, capsule and liquids to newer innovative forms :
Herbal Teas
Instant Energy bars
Ready to Drinks ( RTDs)
Chocolates / Candies
Gummies ( Gelatin ,Pectin or Fruit base )

15. Newer products .. Chewing gums Chewable capsules Lozenges Pastilles
Buccal Films
Sublingual drops
Instant dissolving granules
Biscuits, Cookies and Diskettes
Popsicles and so on…

16. Aloe & Collagen Drink

17. Buccal Films

18. Addresses the role of diet in gene expression
NUTRIGENOMICS
Addresses the role of diet in gene expression

19. Nutrigenomics – Future
Development of personalized foods for the future
The DNA diet (Should your genes decide what you like to eat?)

20. Nutrigenomics – Future
Scientists have identified a few novel Bcl-2 phosphorylating molecules and Cox-II inhibitors from herbal products and functional foods and they are in the process of developing new food products by placing them in the foods

21. Nutrigenomics – Future
e.g.: CoxII cereals (adding Cox II inhibiting nutraceuticals in cereals), CoxII cookies, CoxII juices, CoxII chocolates, Bcl-2 chocolates, candies, cookies, muffins and soft drinks (anti-Bcl-2 Nutraceuticals). Finally, with the presence of more new nutraceuticals in the pipeline than ever before, the juncture between discovery and the effect on genes and proteins is underway

22. Formulations
All parts of our body age but you know the tongue never ages. So the taste is the most important for a Nutraceutical product
Ahara (Food) Anna (Nutrients )
Food prepared with love & affection (care) give more nutrients . So too, are the Nutraceutical formulations

23. THANK YOU