1. 1. Which of the following conditions do human papillomaviruses cause? A. Aplastic crisis B. Keratoconjunctivitis C. Laryngeal papillomas D. All of the above [C] QUIZ 5

2. 2. Which of these viruses is spread by the respiratory or the fecal-oral route, establishes pharyngeal infections, can infect eyes via contaminated fingers, and is the cause of 5-10% of pediatric respiratory infections? A. Adenovirus B. Human papilloma virus C. JC virus D. Parvovirus B19 [A]

3. 3. Class II MHC molecules are present on ___________ and bind exogenous antigenic peptides from ingested and degraded foreign proteins. A. T helper cells B. natural killer cells C. cytotoxic T cells D. antigen presenting cells [D]

4. 4. Which of the following is a growth regulating cellular protein to which papillomavirus E6 and adenovirus E1B proteins bind? A. Transcription factor, NF-kB B. Intercellular adhesion molecule, ICAM C. Eukaryotic initiation factor 2, eIF2 D. Tumor suppressor protein, p53 [D]

5. 5. A particular strain of influenza virus A/PR/8 has a pH optimum for fusion of pH 5.2. Which of the following is the most likely mode of entry of the helical nucleocapsid of the virus into the cytoplasm? A. The virus membrane fuses with the plasma membrane B. The virus membrane fuses with the membrane of a late endosome following acidification of the endosome C. The virus membrane destabilizes, and it destabilizes the plasma membrane D. The virus membrane fuses with the plasma membrane following acidification of the extracellular medium in the respiratory epithelium [B]