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CD40L concentration-dependently binds to Mac-1's I-domain. Wolf D et al. Circulation Research 2011;109: Copyright © American Heart Association
CD40L binds to a distinct binding site within the Mac-1 I-domain. Wolf D et al. Circulation Research 2011;109: Copyright © American Heart Association
The peptide inhibitor cM7 specifically interferes with CD40L-Mac-1 binding. Wolf D et al. Circulation Research 2011;109: Copyright © American Heart Association
CD40L-Mac-1 interaction drives leukocyte recruitment in vivo. Wolf D et al. Circulation Research 2011;109: Copyright © American Heart Association
Specific blockade of the CD40L-Mac-1 interaction attenuates atherosclerosis in mice. Wolf D et al. Circulation Research 2011;109: Copyright © American Heart Association
Inhibition of the CD40L-Mac-1 dyad reduces macrophage and lipid accumulation in atherosclerotic lesions. Wolf D et al. Circulation Research 2011;109: Copyright © American Heart Association
CD40L-Mac-1 interaction does not mediate thrombus formation and stability in mice. Wolf D et al. Circulation Research 2011;109: Copyright © American Heart Association
Circulation Research Feb 3, 2012 Journal Club [Part 1] NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis.
PALS 2010 algorythems. Copyright ©2010 American Heart Association Kleinman, M. E. et al. Circulation 2010;122:S876-S908 PALS Pulseless Arrest Algorithm.
Circulation Research October 2012 Journal Club Gut Microbiota Metabolism of Anthocyanin Promotes Reverse Cholesterol Transport in Mice Via Repressing miRNA-10b.
Slide Source: Lipids Online Pathogenesis of Acute Coronary Syndromes Nathan Wong.
On-going Research Studies in the Rosenfeld Lab *The role of RANK/RANKL in vascular complications of chronic kidney disease Effects of air pollution (diesel.
ATHEROSCLEROSIS Jon Yap John A. Burns School of Medicine Department of Cell and Molecular Biology.
Statins as Protective Agents for Aortic Endothelial Cells Robert Kreisberg West Liberty State College.
Trafficking and processing of APP -secretase. Intracellular trafficking of APP: relation to its physiological function?
Plasminogen Activator Inhibitor-1 Deficiency Prevents Hypertension and Vascular Fibrosis in Response to Long- term Nitric Oxide Synthase Inhibition by.
Critical role for Syk in responses to vascular injury by Patrick Andre, Toshifumi Morooka, Derek Sim, Keith Abe, Clifford Lowell, Nisha Nanda, Suzanne.
Caitlin Cleary Biochemistry Spring ‘12. What is it? A type of arteriosclerosis characterized by changes in the endothelial lining and the formation of.
Date of download: 5/30/2016 Copyright © The American College of Cardiology. All rights reserved. From: Differential Inhibition of Human Atherosclerotic.
Uri Galili PhD, UMass Medical School (retired) A NOVEL APPROACH FOR INHIBITING PROGRESSION OF FLU VIRUS INFECTION AT EARLY STAGES OF THE DISEASE BY INHALATION.
HYPERLIPIDEMIA Coronary heart disease (CHD) is the cause of about half of all deaths. The incidence of CHD is correlated with elevated levels of low-density.
The β2 integrin–kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo by Vicky Louise Morrison, Matthew MacPherson,
Catheter Ablation of Atrial Fibrillation by Roderick Tung, Eric Buch, and Kalyanam Shivkumar Circulation Volume 126(2): July 10, 2012 Copyright.
Atherosclerosis Mike Clark, M.D.. Terms Arteriosclerosis – hardening of the arteries Atherosclerosis – a form of arteriosclerosis Venosclerosis Arteriolosclerosis.
Type IV collagen is an activating ligand for the adhesion G protein–coupled receptor GPR126 by Kevin J. Paavola, Harwin Sidik, J. Bradley Zuchero, Michael.
Elastin Stabilizes an Infarct and Preserves Ventricular Function by Tomohiro Mizuno, Terrence M. Yau, Richard D. Weisel, Chris G. Kiani, and Ren- Ke Li.
순환기질환 - 혈관, 림프관 -. 동맥경화증 arteriosclerosis 나이가 들면서 혈관의 기능이 약화되어 동맥벽의 경화, 비후가 나타나는 만성적 병변을 총칭 죽상동맥경화증 / 세동맥경화증 / 동맥류 aneurysm Aortic Aneurysm.
PBL CV 2 Pathophysiology of coronary artery disease.
Cardiovascular Disease (CVD) Objectives: Describe the movement of blood through the cardiovascular system Discuss the prevalence of CVD Define the types.
Investigation of Fluid Behavior in Bifurcated Microfluidic Chambers Joel Ramey Advisor: Dr. David Schmidtke.
Date of download: 6/22/2016 Copyright © The American College of Cardiology. All rights reserved. From: An Endocrine Genetic Signal Between Blood Cells.
TREM2- and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1 by Qisheng Peng, Shikha Malhotra, James A. Torchia, William G. Kerr,
Inflammation and atherosclerosis Immune cells dominate early lesions Immune effector molecules accelerate lesion progression Activation of inflammation.
Faculty Disclosure Amy J. Arouni, MD, FACC Dr. Arouni has listed no financial interest/arrangement that would be considered a conflict of interest.
Evidence That Estrogen Suppresses Rho-Kinase Function in the Cerebral Circulation In Vivo by Sophocles Chrissobolis, Klaudia Budzyn, Philip D. Marley,
Regulation of Toll-like receptor–mediated inflammatory response by complement in vivo by Xinhua Zhang, Yuko Kimura, Chongyun Fang, Lin Zhou, Georgia Sfyroera,
Trafficking and processing of APP and -secretase.
Phospholipids Analogs as a New Anti-Inflammatory Anti- Atherosclerosis Therapy Dror Harats The Institute of Lipids and Atherosclerosis Research, Sheba.
Omega-3 Fatty Acid Blood Levels by H. Robert Superko, Scott M. Superko, Khurram Nasir, Arthur Agatston, and Brenda C. Garrett Circulation Volume 128(19):
Atherosclerosis. Atheroma are not merely filled with lipid, but contain cells whose functions critically influence atherogenesis: Intrinsic Vascular Wall.
Is Perk involved in the PPAR alpha adaptive response to fasting in the liver? Part I “Peroxisome proliferator-activated receptor alpha mediates the adaptive.
Date of download: 6/23/2016 From: Glucocorticoid Therapy for Immune-Mediated Diseases: Basic and Clinical Correlates Ann Intern Med. 1993;119(12):
Chapter 12 Chapter 12 Parathyroid Hormone and Parathyroid Hormone-Related Protein Copyright © 2013 Elsevier Inc. All rights reserved.
Atherosclerotic lesion area within the aortic sinus of apoE - / - and apoE - / - - hCRP + mice Gideon M. Hirschfield et al. PNAS 2005;102:8309– 8314.
TATIONpRÆSEN AARHUS UNIVERSITY Department of Molecular Biology and Genetics Denmark Danish-Chinese Centre for Proteases and Cancer The Danish National.
Date of download: 6/24/2016 Copyright © The American College of Cardiology. All rights reserved. From: Effects of MF-tricyclic, a selective cyclooxygenase-2.
General, Organic, and Biological Chemistry Copyright © 2010 Pearson Education, Inc.1 Chapter 20 Enzymes and Vitamins 20.4 Enzyme Inhibition.
Pathogenesis of Atherosclerosis Judith Berliner, Ph.D. Departments of Pathology and Medicine Division of Cardiology David Geffen School of Medicine at.
HIC1 attenuates Wnt signaling by recruitment TCF-4 and β-catenin to the nuclear bodies EMBO Journal (2006)
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Trends in Hospitalizations and Outcomes for Acute Cardiovascular Disease and Stroke, 1999–2011CLINICAL PERSPECTIVE by Harlan M. Krumholz, Sharon-Lise T.
Shoot Development A. Function and organization of the apical meristem B. Origin of primary meristems C. Gene regulation at the meristem D. Leaf Initiation.
Figure 1. Illustrating confounders with a directed acyclic graph. A.A. Akinkugbe et al. J DENT RES 2016; Copyright © by International &
GP1b-IX-V 2 GP1α 2 GP1 2 GPIX 1 GPV GPVI -Immunoglobulin superfamily -2 extracellular immunoglobulin-like domain -Binding collagen PLATELET: 2 receptors.
CYTOKINES AND RECEPTORS DR SANJITA DAS. What Is A Cytokine? Low molecular weight proteins (30 KDa) Bind receptors, alter gene expression Can bind the.
Cause : lipid rich plaque; calcified coronary lesion Location of vessel : native coronary artery; renal artery Laterality : Left; Right; bilateral Specificity,
Pulmonary Hypertension and the Right Ventricle George Ruiz, M.D. Director, Pulmonary Vascular Unit Advanced Heart Failure Program.
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