1. IONIZING RADIATION ….. a discussion of the health hazards associated with handling and use of materials capable of producing ionization of matter.

2. Some basics of atomic theory….. Protons - Atomic particle found in an atom’s nucleus possessing a positive charge of +1 Electrons – Atomic particle possessing a negative charge (-1) Neutrons – Atomic particle w/ no electric charge Atomic weight – Sum of protons and neutrons in the nucleus of an atom Atomic number – The number of protons in the nucleus of an atom Isotopes – Nuclei of an element differing in atomic weight but having the same atomic number (e.g., U-235 vs U-238) Radioactivity – The emission of energy in the form of alpha-, beta-, or gamma-radiation from then nucleus of an atom

3. Radiation… Radiation has no unique biological effects. Concept of “half-life” –Time it takes for a radioisotope to lose half its strength

4. Where is data gathered? Early radiation workers Medical personnel who routinely administer radiation for diagnosis or therapy Patients treated with radiation Workers who painted dials with luminous paints containing radium Japanese atomic bomb survivors

5. Where does it come from? Natural, non man-made radiation accounts for more than half of the exposure we receive (rays from sun and stars, earthen materials, in food, etc.). The biggest man-made contribution to radiation exposure of individuals results from the medical and dental use of x-rays and of radioactive materials to diagnose and treat disease.

6. Ionizing vs Non-Ionizing Ionizing radiation * –Radiation capable of producing ions –Comes from x-ray machines, nuclear reactors, and radioactive materials Non-Ionizing radiation –Comes from microwaves, sound waves, light, lasers, radiofrequency, electromagnetic fields, etc.

7. Forms of Ionizing Radiation ALPHA –Travel only a short distance in air (~ 4” in air) –Stopped by dead skin, film of water, sheet of paper –Very hazardous when taken into the body –Avoid inhalation or ingestion BETA –Penetrate human body to depth of 0.1-o.5” –Can penetrate wood to about 1.5” –Stopped by 0.5” aluminum or Plexiglas

8. Forms of Ionizing Radiation (cont.) GAMMA –Deep penetrating –Need steel, lead, etc. to shield X –Radiation –Commonly thought of as electromagnetic radiation produced by an x-ray machine –Penetration depends on wavelength and material being irradiated. –Often use concrete to shield

9. Penetrating Abilities ALPHA - very limited ability; short range in air, stopped by skin BETA - function of originating energy; can penetrate skin GAMMA - highly penetrating; can reach all body organs

10. Specific Ionization ALPHA - large particle and short range --> high S.I. BETA - lower S.I. GAMMA - the lowest S.I. (ionization is a “secondary process” through electrons

11. What occupations are at risk? Healthcare/Medicine –Oncology –Radiation therapy –Dentistry Researchers Miners –Uranium, phosphate, etc. Nuclear power plant employees

12. Symptoms of Exposure High level doses of radiation (generally doses of more than 100 rads), if received all at once, cause short-term effects that appear within hours, days, or weeks. Known as acute radiation syndrome –Initial symptoms: nausea, vomiting, and malaise. –After latent period: infections, fever, hemorrhage, loss of hair, diarrhea, loss of body fluid, CNS effects –>600 rads leads to death Low level doses – risk is proportional to dose, but disagreement or uncertainty about exact responses.

13. Adverse Effects Cancer Birth defects Cataracts Shortening of lifespan If reproductive organs irradiated: –Genetic mutations may occur in sperm or egg cells

14. Damage from Radiation When radiation strikes a cell –It may pass through the cell without doing any damage –It may damage the cell, but the cell partially repairs the damage –It may damage the cell so that the cell not only fails to repair itself but reproduces in damaged form over a period of years –It may kill the cell

15. Factors Determining Damage Amount of radiation absorbed/penetrating ability Amount of body area exposed Energy of the radiation Specific ionization associated with the radiation (how it damages/what it targets)

16. Significant Considerations If the radioactive source is outside the body, control strategies include 1) distance, 2) time, and 3) shielding. If the radioactive source is inside the body, hazard is function of radiation type, energy, half-lives, radiosensitivity of tissues, etc., and control strategies must include all we know about controlling hazards.

17. True or False? Man-made sources of radiation, such as atomic weapons and x-rays have caused new diseases never encountered by medical science.

18. True or False? You can reduce the amount of radiation to which you are naturally exposed by living in a house made of brick, rather than wood.