1. Office of Diversion Control
Drug
Enforcement
Administration
Operations Division
Office of Diversion Control
Denise Curry, J.D.
Deputy Director

2. Drug Addiction Treatment Act (DATA) of 2000
DEA started scheduled regulatory investigations October 1, 2003
Investigations usually last one to two hours
Regulatory investigations are one doctor per diversion group once every fiscal year

3. DATA Waived Practitioners*
DATA Waived Regulatory
Investigations
425 Practitioners as of 12/31/2007
Registered as DATA Waived
*12,826 Practitioners
* as of 01/17/2008 per DEA Oracle Database
Drug Enforcement Administration, Operations Division, Office of Diversion Control

4. DATA Waived Regulatory Investigations
Surrendered Unique Identifier
Practitioner died
Facility where practitioner worked decided too costly to initiate treatment program
Practitioner working for NTP instead of sole practitioner
Practitioner changed his mind
No clients for this service
Psychiatric facility does not allow administering or prescribing office based opiate treatment

5. DATA Waived Regulatory Investigations
Yet to Establish DATA Waived Practice
57 Practitioners
Surrendered Unique Identifier
26 Practitioners
No Problems Cited
253 Practitioners
Problems Cited
74 Practitioners
2007

6. DATA Waived Regulatory Investigations Problems Cited/Action Taken
35Verbal Warnings
record keeping and dispensing violations
23 Letters of Admonition
record keeping and dispensing violations and security violations
8 Surrendered Registrations for Cause2 Show Cause Proceeding
1 Civil Action
5 Undergoing Active Investigations

7. Bubrenorphine Rx
Source: IMS National Prescription Audit retrieved 02/12/08
Thousands
From 2004 thru 2007 there was a 500% increase in buprenorphine prescriptions
Source: IMS National Prescription Audit retrieved 02/12/08

8. Buprenorphine Distribution to Retail Registrants January 1, 2007 – December 31, 2007
Subutex and Suboxone 8mg Tablets
60,436,167 dosage units
71.6%
Subutex and Suboxone 2mg Tablets
18,171,516 dosage units
21.5%
Buprenex and Buprenorphine
Injectables
5,816,281 dosage units
6.9%
Source: ARCOS
Date Prepared: 2/20/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

9. Mid-Level Practitioners Teaching Institutions
Distribution of Subutex and Suboxone (8mg Tablets) to Retail Registrants January 1, 2007 – December 31, 2007
Pharmacies
56,805,196 dosage units
94.0%
Hospitals
2,120,550 dosage units
3.5%
Practitioners
1,068,371 dosage units
1.8%
NTP’s
441,930 dosage units
0.7%
Mid-Level Practitioners
120 dosage units
<0.1%
Teaching Institutions
0 dosage units
0.0%
Source: ARCOS
Date Prepared: 2/20/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

10. Mid-Level Practitioners Teaching Institutions
Distribution of Subutex and Suboxone (2mg Tablets) to Retail Registrants January 1, 2007 – December 31, 2007
Pharmacies
16,320,618 dosage units
89.8%
Hospitals
1,354,488 dosage units
7.5%
Practitioners
298,560 dosage units
1.6%
NTP’s
197,760 dosage units
1.1%
Mid-Level Practitioners
0 dosage units
0.0%
Teaching Institutions
90 dosage units
<0.0%
Source: ARCOS
Date Prepared: 2/20/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

11. 2007 ARCOS Distribution DATA
Buprenorphine
Top 10 States
2007 ARCOS Distribution DATA
GRAMS PER 100K POPULATION
VT ME MA RI CT UT MD PA WV NJ U.S.
Average
Source: ARCOS
Date Prepared: 01/25/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

12. WA MT ND MN OR NY ID SD WI MI WY IA PA OH NE IN NV IL UT CO KS VA CA
Subutex and Suboxone 8mg Tablets Distribution Per 100,000 Population (Pharmacies Only) January - December, 2007 WA
(206)
(VT-148) ME
(258) MT ND V
(NH-46) N
(24)
(12) MN T OR NY H
(MA-651)
(WV-76) MA ID SD
(118) WI
(555)
(1,572)
(151) CT MI
(CT-262)
(24) WY
(8)
(175)
(796) N RI IA PA
(85) J
(17) OH NE DE
(37)
(35)
(26) IN NV IL
(357) W MD UT
(524) CO
(168) KS V VA DC CA
(93) MO
(325)
(70) KY
(164)
(200)
(135)
(48)
(129) NC
(119)
(1,440)
(203)
(NJ-573) TN
(201) OK
(114) AZ NM AR SC
(72) GA
(27) AL
(262)
(139) MS PR LA
(146)
(310)
(139) TX
(98) AK
(189)
(611) FL
(46)
(780)
U.S. Average: 20,451 Dosage Units HI
Above Average = 25,565 Dosage Units or more
Average = 15,338 – 25,564 Dosage Units
Below Average = 15,337 Dosage Units or less
(54)
Numbers in parenthesis represent number of Data Waived Doctors
Source: ARCOS
Date Prepared: 2/20/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

13. State of Massachusetts by Zip Code Subutex and Suboxone 8mg
2007 Pharmacy Purchases of
Subutex and Suboxone 8mg
013
(4)
014
(8)
018
(33)
019
(33)
012
(14)
017
(30)
024
(83)
010
(22)
022
(8)
016
(31)
021
(209)
020
(28)
015
(21)
020
(28)
(22)
011
023
(23)
U.S. Average = 1,708 dosage units
MA Average = 4,917 dosage units
Above = 6,148 dosage units or more
Average = 3,688 – 6,147 dosage units or more
Below = 3,687 dosage units or less
027
(53)
026 (16)
025 (12)
Numbers in parenthesis represent number of Data Waived Doctors
Source: ARCOS
Date Prepared: 02/20/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

14. State of Pennsylvania by Zip Code Subutex and Suboxone 8mg
2007 Pharmacy Purchases of
Subutex and Suboxone 8mg
165
(11)
164
(6)
188
(0)
167
(0)
169
(1)
163
(4)
184
(7)
185
(11)
186
(4)
158
(5)
161
(6)
177
(5)
187
(15)
183
(4)
162
(2)
168
(15)
160
(6)
178
(11)
182
(4)
180
(9)
157
(7)
179
(1)
181
(14)
151
(17)
195
(10)
(17_
150
166
(21)
170
(32)
152
(96)
189
(18)
159
(16)
196
(11)
156
(15)
171
(14)
175
(10)
194
(29)
176
(21)
191
(118)
153
(8)
172
(6)
174
918)
154
(7)
193
(32)
190
(120)
155
(4)
173
(8)
U.S. Average: 1,708 dosage units
PA Average = 2,240 dosage units
Above = 2,801 dosage units or more
Average = 1,680-2,800 dosage units
Below = 1,679 dosage units or less
Numbers in parenthesis represent number of Data Waived Doctors
Source: ARCOS
Date Prepared: 02/20/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

15. Subutex and Suboxone 8mg
325
(22)
324
(4)
323
(6)
320
(28)
322
(54)
State of Florida
2007 Pharmacy
Purchases of
Subutex and Suboxone 8mg
by Zip Code
326
(22)
321
(16)
344
(16)
327(27)
346
(22)
328
336
(50)
347
(14)
335
(10)
(18)
329
337
(33)
338
(15)
342
(27)
349
(25)
339
(27)
334
(112)
U.S. Average = 1,708 dosage units
341
(17)
333
(52)
FL Average = 1,593 dosage units
Above = 1,992 dosage units or more
Average = 1, dosage units
Below = 1,194 dosage units or less
331
(85)
330
(49)
Numbers in parenthesis represent number of Data Waived Doctors
Source: ARCOS
Date Prepared: 02/20/2008
Drug Enforcement Administration, Office of Enforcement Operations, Pharmaceutical Investigations Section, Targeting and Analysis Unit

16. States With the Highest Number of Laboratory Exhibits
(Source: NFLIS - State and Local Forensic Laboratories)
2003
2004
2005
2006
2007
Total MA 4
125
291
501
598
1519 PA 18 39
184
241
482 MD 6 20
108
236
370 NJ 9 37 72
137
258 VA 11 21 45 96
173

17. Buprenorphine Federal, State and Local Laboratory Exhibits (Source: NFLIS and STRIDE)
(54% ↑)
(123% ↑)
(137% ↑ )
(628% ↑)

18. Comments / Questions?