1. © 2010 University of Florida University of Florida Office of Technology Licensing Where Science Meets Business www.otl.ufl.edu

2. © 2010 University of Florida Large Company Large Company Start-Up-Company Medium Size Company Medium Size Company Jobs Profits & Tax Revenue Products & Services % of Revenue % of Revenue Securities Securities Combination Combination The University US, State and Local Governments Local Governments A Very Virtuous Cycle Lab to Market – It Works ! Rapid Genomics

3. © 2010 University of Florida UF-OTL Patents & Licensing Research Awards Invention Disclosures US Provisional Patent Applications Licenses/Options Executed 2008/09 $574M27115172 2007/0856229916775 2006/0758332715674 2005/0651926011573 2004/0549427413366 2003/0447528012164 2002/0345826412752 2001/024281968659 2000/013802046437 1999/002951664328 1998/992801364710 Research Awards Invention Disclosures US Provisional Patent Applications Licenses/Options Executed 2010/11$619M29814578 2009/1067827912067 2008/09 57427115172 2007/0856229916775 2006/0758332715674 2005/0651926011573 2004/0549427413366 2003/0447528012164 2002/0345826412752 2001/024281968659 2000/013802046437 1999/002951664328 1998/992801364710

4. © 2010 University of Florida AUTM Data FY 1991-2006 194,000 disclosures (discoveries) $445B + Research OpportunityAssessment(Triage) 97,000 Patent Apps - 42,000 Issued Patents 35,000 Active Licenses 5,800 Start - ups $2.3M : 1 disclosure 50% do not move forward (16% lics / 3.0% discl.) Positive exit (liquidation) From Disclosure to Patent Royalties (18% of discl.) Attribution: Lou Berneman (Texelerate), updated data from Mike Cleare (U. Penn.) J.Fraser, FSU, 2/15/2010. Commercial potential Commercial potential Technical advantages Technical advantages Protectability Protectability Inventor profile Inventor profile

5. © 2010 University of Florida How Does It Work at UF? Idea Invention Disclosure Form Written Disclosure Oral Disclosure Exert Waive OTL Explores Patentability & Marketability OTL Seeks Licensee & Makes Patent Decisions (120 Days)

6. © 2010 University of Florida Several key elements are necessary to ensure discoveries help benefit society –Protected intellectual property –Further development and testing (almost always) –Commercial partner –Funding for additional R&D –Effective technology transfer services Getting Science from the Lab to the Market – Technology Transfer

7. © 2010 University of Florida Sentricon® is a colony elimination technology for termite control, developed at UF, introduced to market Sentricon® is a colony elimination technology for termite control, developed at UF, introduced to market in 1995 Saved the Statue of Saved the Statue of Liberty from a termite infestation Has also led to a 300 metric ton reduction in chemical use in homes nationwide Has also led to a 300 metric ton reduction in chemical use in homes nationwide

8. © 2010 University of Florida Bayh-Dole Act of 1980 Obligates universities to proactively protect and market their technologies or else forfeit them to the federal funding agency Has stimulated industrial productivity and innovation in the U.S. –Federal agencies prior to Bayh-Dole had a very low rate of success

9. © 2010 University of Florida Types of Patents Utility patent Provides protection for technological advances and innovation. Utility patents apply to the way something is made, how a device operates, or a process for accomplishing some utilitarian purpose. The subject of a utility patent must result from human activity (and not be a product of nature). A machine: e.g., a new medical device to simplify intubation Composition of matter: e.g. DNA/protein sequence or new pharmaceutical A process for making or doing something: e.g. steps for plant transformation

10. © 2010 University of Florida Types of Patents Plant patent Applies to characteristics of a new plant that has been asexually reproduced (by grafting or selective cuttings — without seed manipulation). The specifications include: complete detailed description of the plant and the characteristics that distinguish it from related known varieties its antecedents, expressed in botanical terms the origin or parentage of the plant variety manner the variety of plant has been asexually reproduced A new variety of plant, no matter how reproduced, can also be the subject of a utility patent.

11. © 2010 University of Florida Direct Support Organizations (DSO) Not-for-profit corporation Organized and operated exclusively to receive, hold, invest, and administer property and to make expenditures to or for the benefit of a (FL) state university Organized under part V of chapter 159, FL statutes UF has more than a dozen DSOs that serve specific purposes

12. © 2010 University of Florida To promote, encourage and provide assistance to the research activities of UF faculty, staff and students. UFRF may take equity interests in licensee entities. At UF’s sole discretion, inventions in which university asserts its interests are assigned to UFRF. Licensing of all IP protected by utility patents, trademarks and copyright is carried out through UFRF University of Florida Research Foundation, Inc. (UFRF)

13. © 2010 University of Florida To provide foundation seed and nursery stocks of the best-known varieties adaptable to the Florida climate and soils available annually to Florida farmers and producers in adequate quantities and at reasonable prices. To cooperate with the Florida Agricultural Experiment Station (FAES) of the University of Florida in making available new and improved crop seed and nursery stocks to Florida farmers and producers To propagate and increase the same through any agency, and particularly by contracting with producers and institutions; and to disseminate such increased stocks to it's members and others. Licensing of all IP related to Plant Patents, PVPs, plant breeder’s rights and plant variety rights are carried out through FFSP. Florida Foundation Seed Producers, Inc.(FFSP)

14. © 2010 University of Florida UF’s Organization and IP Policy Clear rules and concrete IP policies in place since 1997 eliminates any disagreements over allocation of money or that a given project is an exception to the rule Differential distribution policy appropriately incentivizes “innovation” and supports programs based on institutional goals Separate licensing personnel and offices for utility patents and plant varieties allows better focus on the specific needs of each program Most utility patents are licensed exclusively and generally there are no state or constituency group issues Most licenses of plant varieties are either non-exclusive or exclusive with expectation of extensive sub-licensing. Additionally, state grower and commodity groups may impact the process and terms

15. © 2010 University of Florida Comparison of Royalty Distribution Schemes Assuming Net License/Royalty Income of $250,000 UFRFFFSP Inventor(s)$100,000$50,000 DSO$87,500$25,000 Breeding Program$25,000$93,330 Experiment Station$18,750$40,830 Department$18,750$40,830

16. © 2010 University of Florida Bridging the Technology Gap Start-ups are often the most appropriate (only) vehicle to bridge the technology gap And Gap Funds are often the only way to get the Start-up Started!

17. © 2010 University of Florida Critical Elements of Technology-Based Economic Development Strong, diverse research programs Technology transfer expertise Business start-up facilities and parks Capital Management

18. © 2010 University of Florida UF Tech Connect program fosters new business creation at UF Match researchers with potential management Assist in business plan creation and market feasibility studies Provide training for “wanna be” entrepreneurs Introduce funding opportunities through VC & angel network introductions Measured base on jobs & private investment Critical Element - Technology Transfer Expertise

19. © 2010 University of Florida Critical Elements – Facilities Incubators for Spin-offs Biotechnology Development Institute - Opened 1995 35,000 sq. ft.; 19 labs, 13 offices Small and large animal facilities 31 companies admitted $42M in equity investment $15M in grant awards 680+ job-years created

20. © 2010 University of Florida Creating An Innovation Ecosystem David L. Day Director, Office of Technology Licensing

21. Close to UF Home to 4,000 faculty who, pulling from a pool of 50,000 talented students, conduct $680 million in research and disclose 300 new discoveries annually

22. © 2010 University of Florida Serial Entrepreneur Focus/Gator Alums –Work closely with foundation Tap Venture Capital and Angel contacts for referrals UF OTL funds Proof-of-Principle experiments to make technologies attractive Pay entrepreneurs to write business plans Host series of meetings – UF Tech Showcase Critical Element - Management

23. © 2010 University of Florida Venture Capital & Public Equity Where We Fit Valley of Death Grants & Sponsored Research BasicResearch,Discovery FeasibilityStudy EngineeringModel ProductDesign ProductDevelopment Regulatory Manufacturing DistributionChannels Market Roll-out Commercialization Bankhead – Coley & King Grants FloridaInstitute SeedFunds Florida Opportunity Fund Florida Growth Fund GapFundsGrowFL

24. © 2010 University of Florida Gatorade is most well- known product from UF Gatorade has maintained 80% market share throughout the better part of the drink’s existence

25. © 2010 University of Florida Igniting Florida’s Innovation Economy “Innovation is the central issue in economic prosperity” Michael Porter, Author, Professor, Harvard Business School

26. © 2010 University of Florida Conclusion Leveraging university research to create companies that create jobs of the future Keeping talented workers employed and retaining them as residents Reducing the brain drain of our students 26

27. © 2010 University of Florida For more information: David L. Day, Assistant V.P. and Director UF Office of Technology Licensing (352) 392-8929 dlday@ufl.edu research.ufl.edu/otl/