1. Biofluid Mechanics and Bioheat Transfer
Malisa Sarntinoranont, Ph.D.
Associate Professor
Department of Aerospace & Mechanical Engineering
University of Florida

2. Biofluid Mechanics & Bioheat Transfer
EGM4592: 3 credit hour undergraduate elective course
Counts towards Biomechanics Certificate offered through Mechanical Engineering
Enrollment senior/juniors
Times taught = 4
EGM6855: 3 credit hour graduate elective course
Enrollment 7
Times taught = once

4. Teaching Goals
My goal in teaching this class is to enable students to apply analysis tools learned in core engineering courses (fluid mechanics and heat transfer) to specific problems of the cardiovascular and temperature regulation systems in the human body.
Problems at various scales are presented and broken down by analysis
non-Newtonian flow through large blood vessels
red blood cell flow through individual capillaries
Students learn current trends in biomedical through final research papers and class presentations.
Graduate level class: modified the course content to include more challenging problems in the field, and greater focus was given to advanced analysis and experimental tools.

5. Syllabus
Textbooks

6. Syllabus continued.
Greater emphasis on biofluids (~8 weeks) compared with bioheat transfer (~5 weeks)

7. Bioheat Transfer topics
Biofluid topics
Bioheat Transfer topics
Basic physiology
Rheology of Blood (different constitutive equations)
Governing equations of flow
Viscous flow through tubes (e.g., Poiseuille flow)
Stenosis
Bifurcations
Oscillating flows
Elastic tubes & wave propagation
Capillary flow
Flow through heart valves
Extracellular flows & lymphatic drainage
Review modes of heat transfer
Conservation of energy
Bioheat equation
Single vessel and paired vessel analysis

8. Projects Journal Paper Review (graduate class)
One student presented a paper review for class discussion each week
Provide students insight of the boundaries of current knowledge
CFD simulation: COMSOL stenosis problem
Term paper & presentation
Students learn current trends in biomedical engineering (from roller coasters to the effects of space flight)

9. Outcomes & Student Feedback
Positive: Students appreciate really understanding & practicing basic fluid dynamic problems (They are generally weak or insecure of their abilities at the start of term)
Positive: Given the limitations of analytical solutions for biomedical applications, computational models provide a more realistic problem-solving scenario which is more satisfying for students
Weakness: Need to emphasize more cell response-related topics:
Immune response/biocompatibility, e.g. thrombosis
Mechanobiology/tissue remodeling, e.g. restenosis

10. Thank You!