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JSC "National Center of State Scientific and Technical Expertise"

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1 JSC "National Center of State Scientific and Technical Expertise"
The results of the project "System analysis and forecasting in the field of science and technology" in "Biotechnology" Expert group: E.B Nikitin S.M. Mamadaliev V.E. Berezin A.K. Bulashev K.K. Mukanov R.T. Omarov L.K. Mamonov E.K. Turuspekov N.N. Belyaeyv Almaty, 2014

2 The purpose of the project:
- Prepare decision makers to change in the future - Identify strategic directions for research and development in biotechnology that will allow Kazakhstan to a new level of development and provide higher living standards and welfare of Kazakhstanis - Assess the threats, risks and opportunities of biotechnology in Kazakhstan in the future The time horizon

3 Main customer groups of the project Ministries and departments
The development of science, technology and innovation policy The choice of priorities in science and technology Investment decisions and budgeting research programs …. National Center of State Scientific and Technical Expertise (NCSSTE) Trends of scientific and technological and innovation development Criteria for evaluation of research projects focused on future development Ranking of scientific projects and programs that meet the challenges and needs of Kazakhstan in the future Formation of a package of projects and programs, highlighting priorities for funding Formation of the global, country and regional research networks Identification of priority areas for the creation of centers of excellence Support for mobility (including international) scientists Fostering growth in the number of publications and patents in the areas that are most important for long-term development Industry Raising awareness about future markets, products, technologies and R & D Strengthening the link between science and business Compliance with business strategies development priorities of the country in the future Science Areas of R & D, new research topics International and in-country mobility, cooperation with leading international research institutes Improving the quality of publications and patents Society Priorities to ensure the welfare of the nation Raising the standard of living of all members of society Improving the education system and development of innovative businesses, providing employment growth

4 Research design System Analysis and Forecasting Scan Scenario planning
Technological analysis Roadmaps Expert panels, interviews, seminars and round tables Bibliometric and patent analysis Research design Сканирование трендов, возможностей, угроз development of biotechnology in the world and in Kazakhstan, SWOT analysis Identification of key factors in the future development Bibliometric and patent analyzes in 1000 the most cited publications and patents (Scopus) Bibliometric and patent analyzes in Kazakhstan (base NCSSTE) Optimistic scenario of development of Kazakhstan up to 2030 2. 8 sectoral scenarios Expert panel on a weekly basis, including more than 60 experts in the context of the 8 sectors Survey of more than 300 Kazakhstan experts Round tables with the participation of over 300 experts Wood technology BMO analyzes Passports of scientific subjects Action Plan (goals, objectives, result in a cut of: 8 sectors more than 20 sub-sectors Macro level (interdisciplinary research programs)

5 Results of the research
Screenplay of biotechnology development in Kazakhstan for the period up to 2030 is the basis for the strategic thinking of options for future development of biotechnology in Kazakhstan based on identifying key trends, opportunities and risks of the future, and variables that have a high uncertainty in future as well List of products / services, technologies and topics of research and development Road maps is the detail work on the development of priority directions of scientific and technological development in the field of health of the nation of Kazakhstan up to 2030 Passports of subjects of research and development

6 Scenario Structure GLOBAL CHALLENGES, TRENDS AND FACTORS OF DEVELOPMENT KAZAKH TRENDS AND FACTORS KEY FOR BIOTECHNOLOGY DEVELOPMENT TRENDS AND FACTORS CROSS-IMPACT ANALYSIS ANALYSIS OF THE FUTURE MARKET IN THE WORLD AND KAZAKHSTAN ANALYSIS OF DEVELOPMENT STRATEGIES AND PROGRAMS OF BIOTECHNOLOGY SECTOR IN THE WORLD ANALYSIS OF STRATEGIES AND PROGRAMS FOR DEVELOPMENT OF THE BIOTECHNOLOGY SECTOR IN KAZAKHSTAN ANALYSIS OF R & D IN THE WORLD, IDENTIFICATION OF COUNTRIES COMPETENCY ANALYSIS OF R & D IN KAZAKHSTAN STRATEGY ON THE SCENARIO "WILD CARDS" AND "WEAK SIGNALS“ OF BIOTECHNOLOGY RISKS AND THREATS TO THE SCENARIO

7 Trends and factors of biotechnology development in Kazakhstan
Future directions of "Biotechnology" in Kazakhstan Society Economy Politics Technology Environment •Population growth, particularly in developing countries •The aging population •The increasing demand for food •The possibility of the development of new and "forgotten" diseases •Increased incidence of socially significant diseases of humans and animals •The growing number of genetic diseases in humans •Continue to develop the trend of urbanization • Reduction of arable land due to urbanization, conservation needs, unsustainable agricultural production and soil degradation • Rising fuel prices and a decrease in reserves of fossil fuels • Availability of unique flora - source of natural medicinal compounds • income growth in developing countries • change of the world market producers of biotechnology products • increased global trade and tourist flows • Soil and water pollution as a result of human activities • Lack of water resources • The amount of carbon dioxide and other greenhouse gases in the atmosphere is increasing - global climate change • The ongoing globalization trends

8 Trends and factors of biotechnology development in Kazakhstan
Population growth, particularly in developing countries Contamination of soil and water as a result of human activities The amount of carbon dioxide and other greenhouse gases in the atmosphere is increasing - global climate change Rising fuel prices and a decrease in reserves of fossil fuels Increasing demand for food The loss of arable land due to urbanization, conservation needs, unsustainable agricultural production and soil degradation Lack of water resources The possibility of the development of new and "forgotten" Diseases Increase in the number of genetic diseases in humans Population aging Change the world market producers of biotechnology products The degree of influence Increase the incidence of socially significant diseases of humans and animals Availability of unique flora - source of natural medicinal compounds Growth of income in developing countries Increased global trade and tourist flows Continue to develop the trend of urbanization Ongoing globalization trends The level of uncertainty

9 The relationship and the mutual influence of factors
Population Growth, particularly in developing countries Contamination of soil and water as a result of human activities Population aging Lack of water resources Malnutrition and hunger on a global scale The amount of carbon dioxide and other greenhouse gases in the atmosphere is increasing - global climate change The possibility of the development of new and "forgotten" Diseases Increase the incidence of socially significant diseases of humans and animals Increase in the number of genetic diseases in humans Continue to develop the trend of urbanization The loss of arable land due to urbanization, conservation needs, unsustainable agricultural production and soil degradation Growth of income in developing countries Rising fuel prices and a decrease in reserves of fossil fuels Change the world market producers of biotechnology products Availability of unique flora - source of natural medicinal compounds Global trade and economic policy Increased global trade and tourist flows

10 The results of analysis of world and Kazakhstan competences in the field of biotechnology Top - 30 countries, actively publishing research in the field of biotechnology Stem cells Analysis of the genome Proteins Renewable biomass Human Genome Pharmaceutical Research Escherichia coli Biofuel Biosensor Biodiesel The search for new medicines Tissue engineering Gold nanoparticles Microbial cells of nutrients

11 The results of analysis of world and Kazakhstan competences in the field of biotechnology The most frequent objects of research in the field of biotechnology Microbial cells of nutrients Gold nanoparticles Tissue engineering The search for new medicines Biodiesel Biosensor Biofuel Escherichia coli Pharmaceutical Research Human Genome Renewable biomass Proteins Analysis of the genome Stem cells

12 The results of analysis of world and Kazakhstan competences in the field of biotechnology Publication activity of Kazakhstan authors in the field of biotechnology in international journals with impact factor

13 The results of analysis of world and Kazakhstan competences in the field of biotechnology The most commonly used objects Kazakhstan biotechnology researchers, published abroad The fourth chromosome Cellulolytic bacteria Biosensor Research The strains of Bacillus Thurigiensis The nuclear genome Biomass Proteins

14 2030: Optimal future for Kazakhstan in the field of biotechnology
Agrobiotechnology Methods of modern biotechnology provide accelerated development of resistance to biotic and abiotic factors of crop varieties;   Veterinary and sanitary conditions of livestock will be provided by domestic diagnostic agents and vaccines of new generation;   Biotechnology processing of agricultural products and agricultural waste will enable obtaining high value added products. Biomedical Cell, post-genome and DNA technologies provide early diagnosis, prevention and treatment of socially significant diseases and the development of personalized medicine;    On the basis of genetic engineering, cell and bionanotechnology effective drugs, preventive and diagnostic preparations will be created ;   Food medical and functionality will be provided through the use of environmentally friendly raw materials and natural sources of Kazakhstan. Industrial Biotechnology Biological methods will be widely use for cleaning oil-contaminated soil and other pollutants and aquatic ecosystems;   Bioconversion based on the use of biological agents and enzymes will reduce pollution by organic waste and get biofuels; Industrial biotechnology, combining production of biofuels, biotechnology, chemical, food and processing industries will get the further development.  Methods of bioleaching of gold, uranium, copper and other precious metals will improve their removal from refractory ores and wastes of mining enterprises;  Biogeotechnology on mining companies will allow to raise sharply the country's competitiveness in the global arena.

15 BASED ON COMPETENCE OF KAZAKHSTAN, for the period up to 2030
Strategy response to the key challenges of the future in the framework of direction "Biotechnology" BASED ON COMPETENCE OF KAZAKHSTAN, for the period up to 2030 Self-development research programs - Agrobiotechnology - Development and introduction of drugs from natural sources - The development of new medicines, preventive and diagnostic preparations of new generation on the basis of DNA technology, cellular and nanotechnologies and monoclonal antibodies - Bioecology - Biogeotechnology Joint research with leading international research centers bioenergetics   The expansion of biotech industries in the field of healthy nutrition The transfer of advanced technologies and adaptation to Kazakhstan - Development and implementation of methods for personalized medicine

16 R & D competence in Kazakhstan biotechnology
High Development of methods for the implementation of personalized medicine The strategic significance A possible mechanism for the development Bioenergy Mostly self-development The expansion of biotech industries in the area of healthy eating Conducting joint research in collaboration with leading centers of the world Medium Agricultural biotechnology Development and implementation of drugs from natural sources Transfer of technology and knowledge Development and implementation of new drugs, preventive and diagnostic drugs of the new generation of DNA-based technologies, nanotechnology and cell monoclonal antibodies Low Bioecology In the short term In the medium term In the long term

17 Identification of priority topics of R & D for Kazakhstan for the period up to 2030 in the direction of Biotechnology The structural composition of the respondents of academic and scientific areas The structural composition of the respondents Representatives of the academic and scientific community Doctors of Sciences PhDs Representatives of the business community Employees of the sphere of scientific activity The ratio of respondents in the age structure Number of experts by age Over 60

18 Priority themes of R & D in the direction of Biotechnology
Product (service) Technologies Topics of research and development Agrobiotechnology Improved animal breeds that have increased productivity and resistance to adverse environmental factors Technology of genomic selection of animals Improved methods of genomic selection of animals Highly resistant plants to abiotic and biotic factors Technology of genetic and cell engineering to improve the properties of commercially valuable plants 1. Development of methods for editing the genomes of commercially valuable plants to give them a sign of increased productivity, resistance to diseases and adverse environmental factors. 2. Development and improvement of methods of cell selection of plants Modern vaccines for the prevention of animal diseases Technologies of creation of recombinant vaccines and tools for managing animal immunity Creating genetically modified microorganisms for use in designing vaccines Modern test systems for the diagnosis of animal diseases and plant diseases Technologies of creation of molecular genetic, cellular and protein diagnostic systems Development of technologies for the production of components for immunodiagnostic test systems

19 Priority themes of R & D in the direction of Biotechnology
Product (service) Technologies Topics of research and development Biomedicine Biomedical cell preparations Technology for production of biomedical cell drugs based on stem cells for regenerative medicine and pharmacology Development of methods for obtaining differentiated cells specific for a cell therapy and drug testing. Artificial organs and tissues that are based on cell and tissue engineering Technology Cell and tissue engineering for regenerative medicine and transplantation Development of technologies for the creation of bioengineered organs and tissues for transplantation. New generation of biopharmaceuticals 1. Technology development of drugs based on recombinant DNA Development of technologies for producing recombinant proteins and peptides with therapeutic properties in prokaryotic and eukaryotic cells. 2. Technology of creation of anticancer drugs Development of technologies for the creation of targeted anticancer drugs based on the products of genetic engineering and cell bioengineering Means and methods of personalized medicine Technology of creation a genetic passport Assessing the role of genetic and environmental factors in the formation of hereditary and multifactorial diseases.

20 Priority themes of R & D in the direction of Biotechnology
Product /service Technologies Topics of research and development Industrial Biotechnology Microbial and enzyme preparations Technology of producing strains biologics Development of technologies for the production of biological products based on producers of biologically active substances for the oil and chemical industry, agriculture and environmental protection. 2. Technology of biocatalysis Development of technologies aimed biocatalysis for the pharmaceuticals and food processing industry and agriculture. New functional foods with high nutritional value and probiotic activity 1. Technology of creation of probiotics and starter cultures The development of new microbial consortia to establish starters for the food processing industry and agriculture, taking into account the ethnic and cultural and regional particularities. 2. Technology of creation of functionally active food supplements Isolation of biologically active substances from native and introduced plant species through the use of biotechnology techniques. Bio- and phytoremediation Technologies for producing strains of microorganisms for bioremediation of environmental objects and restore soil fertility Getting promising strains of microorganisms for bioremediation of soil and restore its fertility.

21 Road map for the direction-Agrobiotechnology
Period of Time 2016 2019 2022 2025 2030 Modern test systems for the diagnosis of animal diseases and plant diseases Modern vaccines for the prevention of animal diseases Products / Services Highly productive plant varieties resistant to abiotic and biotic factors Highly productive breeds of animals that are resistant to diseases and adverse environmental factors Development of methods for editing genomes of commercially valuable species to enhance productivity, resistance to diseases and adverse environmental factors. Development of methods for producing components for immunodiagnostic test systems. Improved methods of genomic selection of animals Research Areas Creating genetically modified microorganisms for use in designing vaccines. Development and improvement of methods of cell selection of plants Methods for detection of immune response to the antigen Genetic engineering research on the modification of genomes Modern methods for DNA genotyping, DNA analyzers of new generation Basic technologies Methods for culture of cells, tissues and organs, haploid technology, cryopreservation, etc. Bioinformatics and Agro Informatics Development of 5 new diagnostic test systems Obtaining a patent on 5 new recombinant strains of microorganisms and viruses The creation and transfer of 5 new technologies on targeted genome modification Transfer of 3 new technologies on a massive parallel SNP-genotyping and bioinformatics Creation of 3 new breeds of animals based on a combination of conventional breeding and genomic technologies indicators Creation of 12 new varieties of crops through a combination of conventional breeding and genomic technologies 35 experts are trained in techniques of genotyping, sequencing and modification of genomes Issue of 3 pilot batches of immune-diagnostic tests Issue of 3 pilot batches of vaccines 25 publications in international journals with high impact factor The acquisition of modern laboratory equipment for molecular genetic and immunological research Financial resources: The State budget, investors, public-private partnerships, international funds Resources Development and improvement of educational programs of undergraduate, graduate and doctoral programs, increasing the number of government grants, engaging in scientific research institute of advanced training Changes to legislation regarding research in the field of molecular genetics and the use of GMOs Research organizations: National Center for Biotechnology, Institute of Plant Biology and Biotechnology, Research Institute for Biological Safety Problems, Institute of Microbiology and Virology, Institute of Molecular Biology and Biochemistry, etc .; Higher education (Nazarbayev University, the KNU, ENU, KazATU, InEU and others.) The leading foreign scientific centers in the field of biotechnology research Russia LLC "Group of companies" Bioprocess "," Institute of stem cells ", Institute of Biochemistry and Physiology of Microorganisms. G.K. Skryabin RAS (Pushchino), All-Russian Research Institute for Animal Welfare (ARRIAH) HFCs "VECTOR" and others US "University of Washington", "Center for Cancer Research im.Freda Hutchinson» (Fred Hutchinson Cancer Research Center "Pacific Northwest National Laboratory," The company Immunex, company Icos, Corixa Company Cooperative Agricultural Program Triticeae USA and others. China China National Center of Biotechnology India Biotechnology Laboratory iTsentry Universities and other countries Strategies / Programs Strategy 2050 State Program FIID of the Republic of Kazakhstan for The strategy of innovative development of Kazakhstan for the period up to 2030 Program "Development of agriculture in the Republic of Kazakhstan for " Risks The need for transfer of new technologies at an early stage; The lack of modern scientific and material base; The need for accredited laboratories; The necessity of using standard consumables for research Personnel risks The lack of a close connection with the production of domestic science High competition from foreign countries The dominance of foreign companies in the field of biotechnology Rise in cost of projects Development of infrastructure and technological base Creation of agrobio clusters and centers for the conservation of genetic resources The development and transfer of new technologies DNA genotyping, cell and genetic engineering The introduction of biotechnology in the agricultural sector Creation of varieties of plants and breeds of animals with improved genetic potential Monitoring Operational plan Strategic plan Long-term vision

22 Roadmap - Biotechnology (sub-direction - "Biomedicine")
Time Products / Services Means and methods of personalized medicine Modern test systems for the diagnosis of human diseases Artificial organs and tissues that are based on tissue and cell engineering Modern vaccines for the prevention of human diseases Biomedical cell preparations A new generation of biopharmaceuticals Assessing the role of genetic and environmental factors in the formation of hereditary and multi factorial diseases Development of methods for obtaining differentiated cells specific for a cell therapy and drug testing Development of technologies for creating targeted anticancer drugs based on the products of genetic engineering and cellular bioengineering Creating genetically modified microorganisms for use in designing vaccines Research Areas Development of technologies for the production of components for immunodiagnostic test systems Development of technologies for the production of recombinant proteins and peptides with therapeutic properties in prokaryotic and eukaryotic cells Development of technologies for the creation of bioengineered organs and tissues for transplantation Cell techniques, immunochemistry, genetic engineering Basic technologies Cell techniques Tissue engineering High Density typing based on the micro fluid PCR technology Hybrid technology, flow cytometry Recombinant DNA technology Recombinant DNA technology Microarray technology, microarray, biosensors High-throughput sequencing, bioinformatics The technology of human iPSCs 300 specialists were trained in the field of biomedical technology Indicators 25 publications in international rating magazines 10 strains producing recombinant proteins and peptides 2 new vaccines and 2 medicines for Health Care 8 PCR and 10 EIA test systems for the diagnosis of human diseases 2 technologies directed to differentiation of stem cells Resources Personnel potential Training of specialists in the country and the organization of training and training at the leading foreign universities and scientific centers on new biomedicine Preparation of 300 highly qualified specialists for biomedicine Skills development through the program "Bolashak" Training in the United States, Germany, France, Britain, Japan, South Korea Infrastructure Development of infrastructure and technological base for the development of biomedicine: the construction of SPF-vivarium for preclinical studies, the construction of cell cryo bank, the creation of two units of cell therapy, the acquisition of modern equipment Leading research institutes and universities Nazarbayev University, Kazakh National Medical University, the Medical University of Karaganda, KazNU, ENU, Karagand State University, the National Center for Biotechnology, Institute of Molecular Biology and Biochemistry, Institute of General Genetics and Cytology, Institute of Microbiology and Virology, Research Institute for Biological Safety Problems, NIITO, the National Science Cardiac Surgery Center , RNC of neurosurgery, RNC of medical emergency, National Center for Maternity and Childhood, National Institutes of Health, USA; University College London, UK; The International Association of Biomedical Gerontology; University of Brighton, UK; Cardiff University, UK; Medicine of Yeshiva University, New York. USA; University of Pittsburgh, USA; Harvard University, Seoul National University Nazarbayev University, Kazakh National Medical University, the Medical University of Karaganda, KazNU, ENU, Karagand State University, the National Center for Biotechnology, Institute of Molecular Biology and Biochemistry, Institute of General Genetics and Cytology, Institute of Microbiology and Virology, Research Institute for Biological Safety Problems, NIITO, the National Science Cardiac Surgery Center , RNC of neurosurgery, RNC of medical emergency Khimfarm, Romat, Nobel, Karaganda pharmaceutical complex Main participants Financial resources 8.8 billion tenge 6.1 bln tenge 3.3 bln tenge Strategies / Programs National Healthcare Development Program "Salamatty Kazakhstan" for State Program FIID of the Republic of Kazakhstan for The strategy of innovative development of Kazakhstan for the period up to 2030 Strategy 2050 The need for transfer of new technologies at an early stage; The lack of modern scientific and material base; The need for accredited laboratories; The necessity of using standard consumables for research Keeping a low level of science funding Personnel risks Risks The lack of a close connection with the production of domestic science High competition from foreign countries The dominance of foreign companies in the field of biotechnology Monitoring Development of infrastructure and technological base Development of infrastructure and technological base Development of infrastructure and technological base Development of infrastructure and technological base Operational plan Strategic plan Long-term vision

23 Roadmap sub- direction "Industrial Biotechnology"
Time New functional foods with high nutritional value and pro biotic activity Microbial and enzyme preparations Products / Services Bio-phytoremediation Development of technologies for the production of biological products based on producers of biologically active substances for the oil and chemical industry, agriculture and the environment Development of new microbial consortia to establish starters for the food processing industry and agriculture with the ethno-cultural and regional characteristics Research Areas Getting promising strains of microorganisms for bioremediation of soil and restore its fertility Isolation of biologically active substances from native and introduced plant species through the use of biotechnology techniques Development of technologies aimed biocatalysis for the pharmaceuticals and food processing industry and agriculture Technology of extraction of organic substances Basic technologies PCR and recombinant DNA techniques Technologies of cultivation and preservation of microorganisms Microbial synthesis, cell biotechnology Indicators 5 new products Obtaining a patent for 3 new recombinant strains of microorganisms Creating 10 new starters microbial consortia Transfer of 3 new technologies for biocatalysis Creation and transfer of 3 new technologies on extraction of biologically active substances 20 publications in international magazines with high impact factor Creating 10 new starters microbial consortia 35 experts were trained in techniques of genotyping of organisms, sequencing and modification of genomes The acquisition of modern laboratory equipment for molecular genetic and microbiological research Financial resources: investors, public-private partnerships, international funds Development and improvement of educational programs of undergraduate, graduate and doctoral programs, increasing the number of government grants, engaging in scientific research institute of advanced training Changes to legislation regarding research in the field of molecular genetics and the use of GMOs Resources Research organizations: National Center for Biotechnology, Institute of Plant Biology and Biotechnology, Research Institute for Biological Safety Problems, Institute of Microbiology and Virology, Institute of Molecular Biology and Biochemistry, etc .; Higher education (Nazarbayev University, the KNU, ENU, KazATU, InEU and others.) The leading foreign scientific centers in the field of biotechnology research Russia LLC "Group of companies "Bioprocess "; Center of Bioengineering RAS; OSM ICC SB RAS; SSC of Russian Federation - IBMP RAS; Institute of Protein Research; Institute of Bioorganic Chemistry; INBI RAS; IBPM RAS and others US "University of Washington", "Center for Cancer Research im.Freda Hutchinson» (Fred Hutchinson Cancer Research Center "Pacific Northwest National Laboratory," The company Immunex, company Icos, Corixa Company, Cooperative Agricultural Program Triticeae USA and others. China China National Center of Biotechnology India Biotechnology Laboratory iTsentry Universities and other countries Strategies / Programs Strategy 2050 State Program FIID of the Republic of Kazakhstan for The strategy of innovative development of Kazakhstan for the period up to 2030 The concept of the development of biotechnology of Kazakhstan Risks - The need for transfer of new technologies at an early stage; The lack of modern scientific and material base; The need for accredited laboratories; The necessity of using standard consumables for research Personnel risks The lack of a close connection with the production of domestic science High competition from foreign countries The dominance of foreign companies in the field of biotechnology Development of infrastructure and technological base Creation of industrial bioclusters Technology transfer biocatalysis, cell engineering Risks of increasing in the cost of projects Implementation of biotechnology in agriculture, environment and natural resources Creating a new generation of biotech products, implementation of biotechnology in the field of environmental protection Monitoring Operational plan Strategic plan Long-term vision

24 Risks and threats to the implementation of the Scenario and Road maps
Scientific and technological risks The emergence of fundamentally new diseases A new class of environmental problems Bioterrorism and eco-terrorism Black markets of Technologies and Bioresources Conflicts between entities and states The lack of concrete decisions in the field of technological development Lack of financial resources allocated to R & D in biotechnology The emergence of new technologies and materials Lowering the prestige of science and the outflow of professionals from the fields of science and production

25 Risks and threats to the implementation of the Scenario and Road maps
Socio-economic risks Low sensitivity of the economy to innovations Inflation, the global economic and financial crisis Low cost business science (mainly focus on adapting imported technologies) Inefficiency forms of financing fundamental and applied sciences Risks of the regulatory framework and infrastructure Risks associated with poor management implementation scenario The risks of a negative attitude towards the implementation of the script on the part of governments, the public and the media Risks of poor quality of the competition to participate in the scenario

26 Risks and threats to the implementation of the Scenario and road maps
Political risks Uselessness of scientific achievements in the economy, patenting abroad The low efficiency of the state support of innovation activity Progressive innovation policy of developed countries Imperfect forms of interaction between government, industry and research centers

27 Measures aimed at reducing the negative impact of risks
Scientific and technological risks - Increasing the reliability of the information provided in the field of biotechnology developments. Improved security in the conduct of research and implementation. Increased patent protection of domestic developments in biotechnology.  Development of efficient technologies and approaches in biotechnology research and production.  Encouraging businesses to introduce biotechnology.  Development of forecasting and priority scientific and technical directions. Constant monitoring of the development of innovative technologies and materials in the industry. Constant maintenance and updating of museums of microorganism strains   Increasing the level of training, their relevance, feasibility of the intellectual potential of young professionals. The implementation of lifelong learning approaches. Socio-economic risks - Establishment of an independent scientific expertise to identify priority projects and the grant and program financing.   The targeted increase in funding for research. - Consistency of the state and the enterprises to overcome the crisis situation. - Development of links between science and industry, update the experimental material and technical base of scientific centers.   Development of priorities and more effective forms of R & D funding Political risks --Application of technological forecasting, creation of favorable conditions for local inventors and innovators, improving and monitoring the implementation of the legal framework for intellectual property. - Improving the existing mechanisms for the selection and funding of innovative projects. - Improving cooperation with the developed countries in the use of new technologies and exchange of scientific and technical information. - Development of mechanisms of interaction between government, industry (domestic and foreign subsoil) and research centers through the creation of scientific and technical advice on directions..

28 Thank you for your attention!!! Almaty January 23, 2014


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