1. Service System for Management and Sharing of Scientific Data in Medicine Depei Liu, Ph.D. Chinese Academy of Medical Sciences

2. Service System for Management and Sharing of Scientific Data in Medicine The system is : The key component of the National Program for Sharing of Scientific Data One of the National Basic Core Platforms for Science and Technology

3. Institutions Responsible Chinese Academy of Medical Sciences Chinese Center for Disease Control and Prevention General Hospital of People’s Liberation Army Chinese Academy of Traditional Chinese Medicine

4. Superior Administrations Department of Basic Research, Ministry of Science and Technology Department of Science, Technology and Education, Ministry of Health Training Bureau of Science and Technology, Department of Health, General Department of Logistics of P.L.A. Department of Science, Technology and Education, State Administration of Traditional Chinese Medicine

5. Objectives of the System To establish Resources of Scientific Data in Medicine To establish Centers of Scientific Data in Medicine To establish Networks of Scientific Data in Medicine

6. Establishment of Resources of Scientific Data in Medicine To integrate available medical data resources and to set up main databases To organize and rescue medical data with scientific value To collect and utilize international resources of medical data To explore and re-utilize data resources

7. Establishment of Centers of Scientific Data in Medicine Macroscopically adjusted and directed by the Government Based on the current academic systems in China Implemented step by step under the uniform layout Adoption of the polices, regulations and technical criteria

8. Establishment of Networks of Scientific Data in Medicine To support the national key programs in science and technology To emphasize data resources in the fields of new and high technology, basic biomedical sciences, and important geographical areas To connect the related professional main databases through Internet To build up the scientific data network with reasonable physical distribution and logistic unification

9. The System Will Cover Most Areas of Medicine Basic medicine, clinical medicine, public health, traditional Chinese medicine, special medicine, meteria medica, innovative drugs, etc. The database for emerging and re-emerging infectious diseases such as SARS will also be included

10. Long-Term Objectives of the System To serve research and education in biomedical sciences and to improve the innovation capability in medical sciences and technology To improve the overall level in prevention, diagnosis and treatment of diseases

11. To enhance the self-protective consciousness of Chinese people and thereby to ensure the entire nation’s health, by opening to the public To strengthen the ability to response to the sudden incidents in public health To provide information for government to make policies and to promote the health care and economic development Long-Term Objectives of the System

12. Working Plan of the System Four Centers/Networks in Phase I Scientific data center for basic medicine Scientific data network for clinical medicine Scientific data center for public health Scientific data center for traditional Chinese medicine A special database for SARS and respiratory diseases

13. Projects in the System Projects Institutions Responsible Service System of Management and Sharing of Scientific Data in Medicine Chinese Academy of Medical Sciences Establishment of the Center of Scientific Data in Basic Medicine Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences Establishment of the Network Center of Scientific Data in Clinical Medicine Peking Union Medical College Hospital, General Hospital, P.L.A.

14. ProjectsInstitutions Responsible Establishment of the Center of Scientific Data in Public Health Chinese Center for Disease Control and Prevention Establishment of the Center of Scientific Data in Traditional Chinese Medicine Chinese Academy of Traditional Chinese Medicine Establishment of the SARS Database and Sharing Chinese Center for Disease Control and Prevention Establishment of the Database of Respiratory Disease and Sharing General Hospital, P.L.A.

15. Mechanism of Organization and Management Model The System will be planned and coordinated as a whole Management and running model featuring the team work of leading, advisory expert and working groups The establishment and running of a center or a network will be carried out by the institutions responsible, in collaboration with related institutions

16. Leading Group The group will include leaders from the institutions responsible, and several professionals in scientific administration The group will be responsible for the decision- making and coordination of the system

17. Advisory Expert Group The group will include experts from the expert committee of the National Program for Sharing of Scientific Data, from institutions responsible, and in the field of scientific data sharing The group will be responsible for steering and authorization of general design, selection of the institutions responsible, as well as phase inspection and evaluation of individual project

18. Working group The group will include members from the working group of the National Program for Sharing of Scientific Data, and principal investigators from the institutions responsible The group will be responsible for the overall design of the project, writing the proposal and report for the project, and actual running of the project

19. Framework in 2003-2004 Service System for Management and Sharing of Scientific Data in Medicine ClassificationCriteriaCatalog System Establishment of the Centers/Networks Establishment of Main Database for Biomedicine Establishment of Main Database for Neuroinformatics and Oncology Establishment of Main Database for Food Ingredients and Hygiene Establishment of Main Database for Modern TCM Scientific Data Center for Basic Medicine Scientific Data Center for Clinical Medicine Scientific Data Center for Public Health Scientific Data Center for TCM Establishment of SARS Database Establishment of Database for Respiratory Disease

20. Tasks in the Period of 2003-2004 Finalize the organization to lead the project, the recruitment of investigators and the mechanism for project management Study and establish the mechanism of co-establishment and sharing of medical scientific data, aiming at different users and levels Collect and analyze the related medical information and technical criteria Study and define collection scope, methods, technical criteria, and data type, data source

21. Study models of data storage and management for medical data units. Compile the catalog, index, and data criteria Study and determine exchange methods and management model Establish a network of medical information, and define interface criteria on database-related service Realize the basic service of database network, including management and affairs processing, definition of interface criteria of knowledge service, distributing browse function for language-sense browser

22. Protein Database Neuroinformatics Database Neoplasm Database Cerebra- cardiovascular Database Acupuncture TCM Database Epidemiology Database Toxicosis Database AIDS Database Gene Database Digital Human Body Database Chinese Herbs Clinical Medicine TCM TCM lectures Preventive Medicine Basic Medicine Diabetes Mellitus Database System of Management and Sharing Service of Scientific Data for Medicine Physiological Constants Database

23. Expected Results To establish a Scientific Data Center/network involved in basic medicine, clinical medicine, public health, and TCM, and to form the running environment of network with reasonable physical distribution and logistic unification To finalize the detailed rules on converge of medical scientific data, the management of data converge, and to provide the sharing service of data To establish Chinese biomedical database, Chinese food ingredients and hygiene database, Chinese neuroinformatics database,and Chinese modern prescription of TCM database

24. To completely utilize the computer network and communication Technology to set up the System and submit the technical report of sharing service To recruit talents with informatics, computer sciences, and medicine, and to strengthen the team pursuing data sharing, in order to meet the requirements of the System To build up the cooperative environment, and to undertake the data sharing service on SARS and respiratory diseases Sharing service benefits governments, institutions of medical, scientific research,and education, and enterprises and public. Sharing service can be offered in the means of free and nonprofitable charge.

25. Thank you for your attention!