Comorbidity There is strong evidence that using certain drugs can trigger either the onset or relapse of schizophrenia in some people. It may also be the case, however, that people with schizophrenia use drugs to overcome negative feelings associated. The rate of substance use is known to be particularly high in this group. In a recent study, 60% of people with schizophrenia were found to use substances and 37% would be diagnosable with a substance use disorder.
Comorbidity Cannabis A recent review has suggested that cannabis use statistically doubles the risk of developing schizophrenia on the individual level, and maybe responsible for up to 8% of cases. Tobacco use People with schizophrenia tend to smoke significantly more tobacco than the general population.