1. International Pancreas Transplant Registry

2. Pancreas Transplants Pancreas Transplants 12/16/1966 – 12/31/2009 nUSA: n = 23,850 nNon USn = 11,365 1/10

3. US Pancreas Transplants USA Pancreas Transplants 12/16/1966 – 12/31/2010 USA: n = 25,031 1/11

4. Number of Tx Centers and Number of Txs 01/11 Transplants USA Pancreas Transplants 1/1/1988 – 12/31/2010

5. Pancreas Transplant Categories USA SPK, PAK and PTA Transplants 1/1/1988 – 12/31/2010 01/11

6. Pancreas Retransplants USA Pancreas Transplants 1/1/1988 – 12/31/2010 1/11 #

7. USA Primary Pancreas Transplants 1/1/1988 – 12/31/2010 Type of Primary and Retransplant

8. Recipient Age USA Primary Pancreas Transplants 1/1/1988 – 12/31/2010 PAK PTA SPK

9. Duration of Diabetes USA Primary DD Pancreas Transplants 1/1/1996 –12/31/2010 PAK PTA SPK

10. Age at Tx by Diabetes Type USA Primary DD Pancreas Transplants 1/1/2006 –12/31/2010

11. Diabetes Type and Duration USA Primary DD Pancreas Transplants 1/1/2000 –12/31/2008

12. Recipient Gender USA Primary DD Pancreas Transplants 1/1/1988 – 12/31/2010 1/11 % Male

13. Patients with Type 2 Diabetes USA Primary DD Pancreas Transplants 1/1/1994 – 12/31/2010 2/11

14. AfricanAmerican Recipients USA Primary DD Pancreas Transplants 1/1/1994 – 12/31/2010 2/11

15. Duct Management Technique USA DD Primary Pancreas Transplants 1/1/1988 –12/31/2010 2/11

16. Portal Drainage in ED Txs USA DD Primary Pancreas Transplants, 1/1/1988 – 12/31/2010 2/11

17. Use of a Roux-Loop in ED Txs USA Primary DD Pancreas Transplants, 1/1/1996 – 12/31/2010 2/11

18. HLA A,B,DR Mismatching USA Primary DD Pancreas Transplants 1/1/1988 – 12/31/2010 3/11 % of 5 or 6 HLA Mismatch

19. Anti-T-Cell Induction USA DD Primary Pancreas Transplants 1/1/1988 – 12/31/2010 2/11

20. Class I PRA levels > 20% USA DD Primary Pancreas Transplants 7/1/2004 – 12/31/2010 2/11

21. Class II PRA levels > 20% USA DD Primary Pancreas Transplants 7/1/2004 – 12/31/2010 2/11

22. SPK Induction Antibody Therapy USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2010 3/11

23. PAK Induction Antibody Therapy USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2010 3/11

24. PTA Induction Antibody Therapy USA DD Primary Pancreas Transplants 1/1/2000 – 12/31/2010 3/11

25. Antibody Therapy USA Primary DD Pancreas Transplants 1/1/2006 – 12/31/2010 No ABs Depl. AB NonDepl. AB Both ABs 3/11

26. Overall Initial Steroid Avoidance USA Primary DD Pancreas Transplants 1/1/2000 – 12/31/2010 3/11

27. Major Immunosuppressive Protocols USA Primary DD Pancreas Transplants 1/1/2006 – 12/31/2010 3/11