1. Biology in Silico : Online Tools for “Omics” WCRC RETREAT SEPTEMBER 6TH, 2014 ANSUMAN CHATTOPADHYAY, PHD HEAD, MOLECULAR BIOLOGY INFORMATION SERVICE HEALTH SCIENCES LIBRARY SYSTEM UNIVERSITY OF PITTSBURGH

2. Topics HSLS Molecular Biology Information Service Library Licensed Bioinformatics Tools Search Engine, InfoBoosters & ReadingAssist

3. http://hsls.libguides.com/wcrc

4. Information Overload 285K Breast Cancer 110K Schizophrenia 11K BRCA1 73 K p53

5. Information Overload

6. Molecular Biology Information Service

7. 1990-1996 University of Nebraska-Lincoln PhD. in Biochemistry Protein synthesis initiation in eukaryotic system 1997-2001 Vanderbilt University School of Medicine, Nashville Research Fellow Epidermal Growth Factor (EGF) mediated signal transduction 2001-2002 Cellomics Inc., Pittsburgh Knowledge Engineer 2002- 2006 Information Specialist in Molecular Biology and Genetics HSLS, University of Pittsburgh Ansuman Chattopadhyay, Ph.D. ansuman@pitt.edu 2006- Present Head, Molecular Biology Information Service HSLS, University of Pittsburgh

8. Bioinformatics Service @ Health Sciences Libraries 1994 : University of Washington 2002: University of Pittsburgh 2006 … University of Florida, Gainesville Washington University, St. Louis Northwestern University, Chicago University of Southern California, LA University of California, San Francisco Harvard University University of Rochester ……………………

9. WorkshopsWeb Dev Software Licensing Bioinformatics Consultations Molecular Biology Information Service http://www.hsls.pitt.edu/molbio 4

10. In silico Support Literature Search Sequence Analysis Omics Data Analysis

11. Molecular Biology Information Service HSLS Licensed Bioinformatics Software

12. Software Access http://www.hsls.pitt.edu/molbio

13. ePath3D

16. Bioinformatics Workshops CLCBio – RNA Seq.. October 7 th, 2014 CLCBio – Exome, Whole Genome Seq, October 8 th,2014 UCSC Genome Browser Road Show.. December 4 th,5 th, 2014

17. Life Sciences Search Engine InfoBoosters ReadingAssist Web Development

18. Search Engine for Life Scientists http://www.hsls.pitt.edu/molbio

19. Database Issue Web Server Issue Software and Database articles Search Engine for Life Scientists

20. Databases/Tools : CRISPR

21. how is it calculated ? what is its function ? what is its structure? Challenges for Biomedical Scientists

22. InfoBoosters www.hsls.pitt.edu/infoboosters

23. InfoBoosters

25. Infoboosters

27. InfoBoosters How is it calculated ? What is its function ? What is its structure?

28. Data Integration InfoBoosters

29. Create Your Own InfoBooster WWW.hsls.pitt.edu/infoboosters

30. InfoBooster Generator Clinical Trials.gov

31. InfoBooster Generator Go to the Clinical Trials.gov Website and do a search with a one-word search term, such as asthma 1 1

32. InfoBooster Generator COPY the URL from the search result page 2 2

33. InfoBooster Generator 3 3 4 4 5 5 WWW.hsls.pitt.edu/molbio/infoboosters

34. InfoBooster Generator

36. ReadingAssist

39. Contact US

40. Thank You