1. The results of diode Laser treatment for posterior retinopathy of prematures Piozzi E. Mazza M. Del Longo A. Niguarda Hospital MILAN S.C. Pediatric Ophthalmology Chief E. Piozzi MD

2. Laser photocoagulation is Laser photocoagulation is the treatment of choice for treshold retinopathy of prematurity (ROP) the treatment of choice for treshold retinopathy of prematurity (ROP)

3. LASER treatment We treated 50 eyes of 25 babies with diode Laser (810 nµ) or green Laser (532 nµ) from July 2000 to October 2005. We treated 50 eyes of 25 babies with diode Laser (810 nµ) or green Laser (532 nµ) from July 2000 to October 2005.

4. 44 eyes ROP stage 2-3 plus 6 eyes ROP zone I (AP-ROP) 6 eyes ROP zone I (AP-ROP) The International Classification of Retinopathy of Prematurity Revisited An International Committee for the Classification of Retinopathy of Prematurity* Arch Ophthalmol. 2005;123:991-999.

5. ROP plus

6. Different from classic ROP AP-ROP

7. AP-ROP  Zone I  Flat network neovascularization  Naked shunts  Early plus  No stages  Rapidly progressive

8. AP-ROP Plus is indication to laser

9. Laser Treatment Parameters: Power 150-200 mW Duration 0.1-0.2 sec. Number 1500-2000 spots

10. Laser treatment The pattern of Laser photocoagulation The pattern of Laser photocoagulation burns to the avascular retina is : burns to the avascular retina is : -confluent or -confluent or -near confluent -near confluent to avoid skip areas. to avoid skip areas.

11. Laser treatment Laser photocoagulation was performed under general anesthesia Laser photocoagulation was performed under general anesthesia

12. NGAWSTAGEEVOLUTION PG25780 OO st 3 plus OS 4 A RS31+41200 OO st 2 zona II plus FAVORABLE PL25+5650 3 plus FAVORABLE MB25630 3 plus zona II-III FAVORABLE NV25850 3 plus FAVORABLE PP24+4710 3 plus zona II FAVORABLE PD26850 2 plus zona II FAVORABLE TD291000 2 plus zona II-II FAVORABLE CC23610AP-Rop OD 4 A-OS 5 GM26750AP-ROPFAVORABLE LY30930 3 plus FAVORABLE PM25730 FAVORABLE PR26750 FAVORABLE GC26720 FAVORABLE CA25770 2 zona II plus FAVORABLE GA271000 OD 2 plus OS 3 plus FAVORABLE SD26+6630 2 plus zona 1 OD 4 A-OS 5 DS25700 3 plus zona 1 FAVORABLE VN26924 2 plus zona 2 FAVORABLE ZF24665 3 plus OD 4 A GA26953 3 plus zona II FAVORABLE FM24620 2 plus zona I-II FAVORABLE CM25760AP-ROP OO 5 SA25815 3 plus FAVORABLE

13. Only two eyes (4%) needed Supplemental Laser treatment. Only two eyes (4%) needed Supplemental Laser treatment.

14. RESULTS 42 favorable outcome (84%) 4 eyes progress to stage 4 A 4 eyes progress to stage 5

15. RESULTS 6 eyes AP-Rop 2 favorable outcome (34%) 4 unfavorable (66%)

16. CONCLUSIONS Laser photocoagulation is associated with a good anatomic outcome. Laser photocoagulation is associated with a good anatomic outcome. ROP more posterior is difficult to treat successfully with ablative therapy. ROP more posterior is difficult to treat successfully with ablative therapy.

17. MOVIE MOVIE

19. Thank-youThank-you