1. HORIZON 2020 The EU Framework Programme for Research and Innovation 2014-2020
Presentation to NUI Galway
10 September 2013
Kay Duggan-Walls, Health Research Board
National Contact Point for Horizon 2020 Health

2. Proposal for H2020
Legislative proposal from Commission was announced 30 November 2011 Part of a drive to create new jobs and growth in Europe

3. What is Horizon 2020?
Commission proposal for a €80 billion research and innovation funding programme ( )
A core part of Europe 2020, Innovation Union & European Research Area:
Responding to the economic crisis to invest in future jobs and growth
Addressing people’s concerns about their livelihoods, safety and environment
Strengthening the EU’s global position in research, innovation and technology

4. Horizon 2020 – What’s New
A single programme bringing together three separate programmes/initiatives*
Coupling research to innovation – from research to retail, all forms of innovation
Focus on societal challenges facing EU society, e.g. health, clean energy and transport
Simplified access, for all companies, universities, institutes in all EU countries and beyond
*The 7th Research Framework Programme (FP7), innovation aspects of Competitiveness and Innovation Framework Programme (CIP), EU contribution to the European Institute of Innovation and Technology (EIT)

6. Three Priorities Excellent Science Industrial leadership
Societal challenges
ERC – frontier research by the best individual teams
Future and emerging technologies – Collaborative research to open new fields of innovation
Marie Curie actions – Opportunities for training and career development
Research infrastructures ensuring access to world class facilities

7. Priority 1. Excellent science €25bn
Why:
World class science is the foundation of tomorrow’s technologies, jobs and well-being
Europe needs to develop, attract and retain research talent
Researchers need access to the best infrastructures
European Research Council
Frontier research by the best individual teams
€13,263
Future and Emerging Technologies
Collaborative research to open new fields of innovation
€3,100
Marie Curie actions
Opportunities for training and career development
€5,752
Research infrastructures including e-infrastructures
Ensuring access to world class facilities
€2,478

8. Priority 2. Industrial leadership €18bn
Why:
Strategic investments in key technologies (e.g. advanced manufacturing, micro-electronics) innovation across existing and emerging sectors.
Europe needs to attract more private investment in research and innovation
Europe needs more innovative SMEs to create growth and jobs
Leadership in enabling and industrial technologies (ICT, nanotechnologies, materials, biotechnology, manufacturing space)
€13,781
Access to risk finance
Leverage private finance and venture capital for research and innovation
€3,538
Innovation in SMEs
Fostering all forms of innovation in all types of SMEs
€619

9. Priority 3. Societal challenges €32bn
Why:
Concerns of citizens and society/EU policy objectives (climate, environment, energy, transport etc.) cannot be achieved without innovation
Breakthrough solutions come from multi-disciplinary collaborations, including social sciences & humanities
Promising solutions need to be tested, demonstrated and scaled up
Health, demographic change and wellbeing
€8,033
Food security, sustainable agriculture, marine and maritime research & the bio economy
€4,152
Secure, clean and efficient energy
€5,782
Smart, green and integrated transport
€6,802
Climate action, resource efficiency and raw materials
€3,160
Inclusive, innovative and secure societies
€3,819

10. Horizon 2020

11. Horizon 2020 and partnering: an overview
Public private partnerships
Through Joint Technology Initiatives (JTIs) or other formal structures (Art 187)
Through contractual agreements, which provide input for work programmes
Only when criteria met, e.g. clear commitment from private partners
Public public partnerships:
Through ‘ERA-Nets’ for topping up individual calls/actions (replacing current ERA-Net, ERA-Net Plus, Inco-Net, Inno-net)
Through participation in joint programmes between Member States (Art. 185)
Supporting agendas of Joint Programming Initiatives when in line with Horizon 2020
Only when criteria met, e.g. financial commitments of participating countries
European Innovation Partnerships
Not funding instruments, but for coordination with broader policies and programmes

12. FP7 Cooperation themes → HORIZON2020 challenges
Health (€6.1b)
Food, agriculture, fisheries and biotechnology
Information and communication technologies
Nanosciences, nanotechnologies, materials and new production technologies
Energy
Environment (including climate change)
Transport (including aeronautics)
Socio-economic sciences and the humanities
Security
Space
The Health, Demographic Change and Well-being Challenge (€7bn over 7 yrs)
The Food Security and Bio-based Economy Challenge
The Secure, Clean and Efficient Energy Challenge
The Smart, Green and Integrated Transport challenge
The Resource Efficiency and Climate Challenge
The Inclusive, Innovative and Secure Societies Challenge

13. The Health, Demographic Change and Well-being Challenge
Basic research through translation of knowledge, to large trials and demonstration actions
Broader scope than FP7
More ICT aspects
Public procurement for new products, services, scalable solutions (interoperable and supported by defined standards and/or common guidelines) – haven’t had this before in Health

14. Specific activities proposed
1.1. Understanding health, wellbeing and disease
Understanding the determinants of health, improving health promotion and disease prevention
Understanding disease
Improving surveillance and preparedness
1.2. Preventing disease
Developing effective  prevention and screening programmes and improving the assessment of disease susceptibility
Improving diagnosis and prognosis
Developing better preventive and therapeutic vaccines
1.3. Treating and managing disease
Treating disease, including developing regenerative medicine
Transferring knowledge to clinical practice and scalable innovation actions

15. Specific Activities proposed
1.4. Active ageing and self-management of health
Active ageing, independent and assisted living
Individual awareness and empowerment for self-management of health
1.5. Methods and data
Improving health information and better use of health data
Improving scientific tools and methods to support policy making and regulatory needs
Using in-silico medicine for improving disease management and prediction
1.6. Health care provision and integrated care
Promoting integrated care
Optimising the efficiency and effectiveness of healthcare provision and reducing inequalities by evidence based decision making and dissemination of best practice, and innovative technologies and approaches

16. Proposed Work Programme Cycle
2014
2015
2016
2017
2018
2019
2020
Strategic Programme
Work Programme 1
(plus tentative information for 2016)
Work Programme 2
(plus tentative information for 2018)
Work Programme 3
(plus tentative information for 2020)
Work Programme 4
First calls mid-December

17. Strategic Programme for the 2014-2016 Work Programme

18. Horizon 2020 Work Programme
Horizon 2020 is different
Multidisciplinary approach
Strong challenge based approach – allowing applicants freedom to come up with innovative solutions
Simplified list of possible type of action (research and innovation 100%; innovation actions – 70%)
Less prescription, strong emphasis on expected impact
Broader topics
Cross-cutting issues mainstreamed (e.g. social science, gender)

19. Personalised Health and Care
Choice to focus on personalised health and care – informed by ageing of the European population
Increasing communicable and non-communicable disease burden
Fall out from economic crisis
Aims to create opportunities for real breakthrough research and radical innovation
Supporting translational of findings into clinic and other healthcare settings to improve health outcomes, reduce inequalities and promote active and healthy ageing

20. Rational for 1st Work Programme
Demographic changes
Chronic diseases
Sustainability of health and care systems – cost of inaction
Drug development pipeline
Infectious disease – in terms of global development, resurgence, pandemic threat
Big data

21. Work programme Topics Structure reflects the challenge based approach
Specific Challenge – sets the context, the problem to be addressed, why intervention is necessary
Scope – delineates the problem, specifies the focus and the boundaries of the potential action BUT without overtly describing specific approaches
Expected Impact – describe the key elements of what is expected to be achieved in relation to the specific challenge

22. Work Programme Summary
Understanding health, ageing and disease – 2 topics
Effective health promotion, disease prevention, preparedness and screening – 6 topics
Improving diagnostics – 3 topics
Innovative treatments and technologies – 6 topics
Advancing active and healthy ageing – 3 topics
Integrated, sustainable, citizen-centred care – 7 topics
Improving health information, data exploitation and providing an evidence-base for health policies and regulation – 5 topics

23. Work Programme
Societal challenge ‘Health demographic change and wellbeing’
2014 & 2015, 32 topics the ‘personalised health and care’ focus area call
10 topics in the ‘co-ordination activities’ call

24. Work Programme Topics
PCH 1 – Understanding health, ageing and disease: determinants, risk factors and pathways
PCH 2 – Understanding health, ageing and disease: systems medicine
PCH 3 – Health promotion and disease prevention: improved inter-sector cooperation for environment and health based interventions
PHC 4 – Health promotion and disease prevention: translating ‘omics’ into stratified approaches

25. Work Programme Topics cont.
PHC 5 – Evaluating existing screening and prevention programmes
PHC 6 – Improving the control of infectious epidemics and foodborne outbreaks through rapid identification of pathogens
PHC 7 – Vaccine development for poverty-related and neglected infectious diseases: Tuberculosis
PHC 8 – Vaccine development for poverty-related and neglected infectious diseases – HIV/AIDS
PHC 9 – Development of new diagnostic tools and technologies: in vitro devices, assays and platforms
PHC 10 – 2015 Development of new diagnostic tools and technologies: in vivo medical imaging technologies

26. Work Programme cont.
PHC 11 – 2014 and 2015 Clinical validation of biomarkers
PHC 12 – 2014 New therapies for chronic and non-communicable diseases
PHC 13 – 2015 New therapies for rare diseases
PHC 14 – 2014/15 Clinical research on regenerative medicine
PHC 15 – 2015 Tools and technologies for advanced therapies
PHC 16 – 2014 Comparing the effectiveness of existing healthcare interventions in the elderly

27. Work Programme cont.
PHC Establishing effectiveness of health care interventions in the paediatric population
PHC 18 – 2014 Advancing active and healthy ageing with ICT: Service robotics within assisted living environments; and ICT solutions for independent living with cognitive impairment
PHC 19 – 2015 Advancing active and healthy ageing with ICT: Early risk detection and intervention
PHC 20 – 2015 Promoting mental wellbeing: in the ageing population

28. Work Programme cont.
PHC 21 – 2014 Developing and comparing new models for safe and efficient, prevention orientated, health and care systems
PHC 22 – 2015 Piloting personalised medicine in health and care systems
PHC 23 – 2015 Advanced ICT systems and services for integrated care
PHC 24 – 2014 Self-management of health and disease: citizen engagement and mHealth
PHC 25 – 2015 Self-management of health and disease: decisional support systems and patient empowerment supported by ICT
PHC 26 – 2015 Public procurement of innovative eHealth services

29. Work Programme cont. PHC 27 201? eHealth Sectoral Prize
PHC 28 – 2015 Digital representation of health data to improve diseases’ diagnosis and treatment
PHC 29 – 2014 Foresight for health policy development and regulation
PHC 30 – 2014 Advancing bioinformatics to meet biomedical and clinical needs
PHC 31 – 2015 New approaches to improve predictive human safety testing
PHC 32 – 2014 eHealth interoperability

30. Co-ordination activities
HCO Innovative Partnership: Support for the European Innovative Partnership on Active and Health ageing
HCO 2 – 2014 Joint Programming: Coordination Action for the Joint Programming Initiative (JPI) ‘More Years, Better Lives – the Challenges and Opportunities of Demographic Change’
HCO 3 – 201? Support for the European Reference Networks: Efficient network modelling and validation
HCO 4 – 2014 Support for international infectious disease preparedness research
HCO 5 – 201? Global Alliance for Chronic Diseases: Prevention and treatment type 2 diabetes

31. ERA-NETs
HCO 6 – 2014 ERA-NET Establishing synergies between the Joint Programming on Neurodegenerative Disease Research and Horizon 2020
HCO 7 – 2014 ERA-NET: Cancer research programmes and activities
HCO 8 – 2014 ERA-NET: Brain related diseases research programmes and activities
HCO 9 – 2014 ERA-NET: Systems medicine for clinical needs research programme and activities
HCO 10 – 201? ERA-NET: Rare disease research implementing IRDiRC objectives

33. Budget Horizon 2020 - €70bn over 7 years
SC1 (health) - €7bn over 7 years
first 2 years – only €1bn across 32 topics
15% of budget ICT topics
1/3 of funding will be provided for ERA-NETs

34. Horizon 2020 is different
Web portal with one entrance for the Programme
Counting on MS to explain to researchers – need to look at entirety of the programme not just SC1
ERC – increase in budget to €15.6bn- 20% ~ life sciences – may be first port of call
Encouraged to look at other schemes

35. Timeline Commission published Horizon 2020 package on 30 Nov 2011
Council agreed ‘Partial General approaches’ on Regulation in May; on the Rules in October and the Specific Programme in December 2012
The ITRE Committee of Parliament proposed amendments in November 2012
‘Adoption of Horizon 2020 legislative acts expected at end 2013
First calls: expected mid-December
Structure H2020 programme committees to be agreed
Health Advisory Groups to be established
Nominations for NCPs have been sought
Structure h2020 programme committes to be agreed
Health Advisory Groups to be established
Nominations for NCPs

36. Ireland’s Results FP7 Health
490 participations
28 successful coordinators
117 successful partners
15.5% funding ~ 4 clinical trials projects
Total funding in FP7 Health - €77.68m
Ireland target €600 million ~ €502 million
Health target 1.25% - exceeded 1.7%

37. Ireland’s FP7 Health Participation 2007-2013 €77.68m
FP7 Call A
FP7 Call B
FP7 Call
FP7 Call
FP7 Call
FP7 Call
FP7 Call
Second Stage
Number of individual participations
- Partners
- Coordinators 74 71 3 93 82 11 64 7 62 49 13 58 48 10 44 14 63
Successful coordinators 4 1
10‡
Successful partners¥ 17 15 9 20 21 22
Project Success rate
24%
TS*50%$
TS* 80%$
TS* 40.9%
Innov1# 42.5%, Innov2& 60%
Innov1# 43%
Innov2& 0%
EU success rate
17%
20%
TS*42%$
TS* 41%$
Innov1# 39%, Innov2& 42%
Innov1# 35%
Innov2& 32%
Total Budget available
€637m
€549m
€591m
€628m
€662m
€657.6m
€819.3m
Total Funding to Ireland
€6m
€5.88m
€4.4m
€17.4
€13.6
€18.6
€11.8
** TS = Two stage , $ at second stage, # Innovation 1 call, & Innovation 2 call (SME focused), ¥ Some projects have multiple Irish Partners,
‡ Highest success rate for coordinators in EU (71.4%)

38. Health NCPs for Ireland
Kay Duggan-Walls
Health Research Board
Ciaran Duffy
Enterprise Ireland
Patricia Clarke (National Delegate)
Meet regularly – meetings/teleconference/

39. For further information contact
Kay Duggan-Walls
tel (01)