Presentation on theme: "Dr Hassan Makki DO FACC Phoenix Heart Center. Diabetes mellitus (DM) is a group of diseases characterized by high levels of blood glucose resulting."— Presentation transcript:
Diabetes mellitus (DM) is a group of diseases characterized by high levels of blood glucose resulting from defects in insulin production, insulin action, or both. The term diabetes mellitus describes a metabolic disorder of multiple causes characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
At least 10.3 million Americans have been diagnosed with diabetes mellitus, and another 5.4 million are estimated to have undiagnosed diabetes. Onset often precedes diagnosis. 90% of diabetic patients have Type II diabetes Hispanics 11 %, African Americans 10%, Native Americans, and Asians Diabetes in women essentially cancels out any hormonal protection (up to 13%).
Makes cholesterol particles smaller, stickier and more plaque forming Sugar molecules actually directly (and indirectly) damages artery walls Sets up a Pro- Inflammatory and Pro- Clotting environment Hormone activation of immune cells
~80% of all diabetic mortality 75% from coronary atherosclerosis 25% from cerebral or peripheral vascular disease >75% of all hospitalizations for diabetic complications >50% of patients with newly diagnosed type 2 diabetes have heart or vascular dz
Impaired Fasting sugar (>100) or Post meal (>200), HGAIC less than 5.7 HGAIC >6.0 Full blown DM Diet exercise, follow up Start DM Meds Start HEART MEDS!
ASA STATINS BP meds ACE inhibitors 17% reduction in cardiac/vascular events 52% reduction vs 32% in non DM 51% reduction when diastolic less than 80-85
Diabetics are a delicate population with serious medical problems. Problem is an epidemic! Early detection and appreciation is key High index of suspicion is required when diabetics have any symptoms….or not having symptoms. Aggressive risk modification upstream prevents problems downstream Very preventable disease!