S.Capri - LIUC University Competitive environment The increase of cost and length of the R&D process The increase of internal competition The advent of generic medicines The expiration of patents The price regulation The advent of personalised medicines
S.Capri - LIUC University From Laboratory to Patient: The Complex Pathway of Biopharmaceutical R&D Pharmaceutical Industry Profile 2005 (Washington, DC: PhRMA, March 2005).
S.Capri - LIUC University Biopharmaceutical R&D Expenditures and NIH Budget: 1994–2004 Pharmaceutical Industry Profile 2005 (Washington, DC: PhRMA, March 2005).
S.Capri - LIUC University The period of market exclusivity between the introduction of a breakthrough medicine and of a competing product is rapidly shrinking
S.Capri - LIUC University The expiration of patents Generic erosion
S.Capri - LIUC University Price differences among European countries
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