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EDEN Integrated Project proposal Emerging Diseases in a changing European Environment Florence Putterman.

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Presentation on theme: "EDEN Integrated Project proposal Emerging Diseases in a changing European Environment Florence Putterman."— Presentation transcript:

1 EDEN Integrated Project proposal Emerging Diseases in a changing European Environment Florence Putterman

2 The European Union is expanding to incorporate states with significantly different working environments, agricultural practices and human and animal disease profiles. At the same time, the earth's climate is in a warming phase, a part of which may be due to human activities. Some models suggest that this phase will continue, with effects that will be especially pronounced in temperate regions. Both local and global changes may independently or in combination have an impact on human/animal health, by favouring the spread of diseases already found in Europe, or the re-emergence of diseases long dormant here.

3 Predicting the next emerging or re-emerging disease is virtually impossible, but we can and should prepare now both the methods for monitoring the changing epidemiological landscapes of Europe and the tools that must be brought into action quickly once new diseases appear. Of all the diseases potentially in this grouping, it is expected that those involving intermediate hosts, insects, ticks or other vectors, will be the most important.

4 EDEN call

5 FP6 call The aim is to identify, evaluate and catalogue European ecosystems and environmental conditions linked to global change, which can influence the spatial and temporal distribution and dynamics of pathogenic agents. A coordinated European approach is needed to provide predictive emergence and spread models including global and regional prevention, early warning, surveillance, and monitoring tools and scenarios. Coordination with international organizations and third world countries is essential.

6 The aim is to identify, evaluate and catalogue European ecosystems and environmental conditions linked to global change and which can influence the spatial distribution the temporal distribution and the dynamics of pathogenic agents. Predictive emergeance and spread models including the following tools and scenarios: - Global and Regional prevention - Early warning - Surveillance - Monitoring Coordination with international organisations and third world countries. Keywords Coordinated European approach

7 EDEN project

8 Africa Plateform – new strains of West Nile Virus and new diseases such as Rift Valley Fever may be introduced to Europe from tropical regions linked by bird and other (e.g. traded livestock) migratory routes to Europe. Tick-borne Diseases – diseases already present in Europe that have shown significant recent increases in incidence, at least partly due to changes in human behaviour in relation to the environment. Rodent-borne Viruses (hanta, arena, cowpox) – widespread but under-reported diseases within Europe, with strong links with habitat and landscape structures. Leishmaniasis – persistent on the southern fringes of Europe and beyond (southern Mediterranean basin), with the potential to expand as environments change. West Nile Virus – periodic and occasionally severe local outbreaks, especially on the eastern fringes of Europe, currently showing strong associations with landscape patterns. Malaria – an ancient scourge of Europe, currently now on her southern and eastern fringes, with the potential for re-emergence following environmental changes. Indentify a set of Indicator diseases

9 WP / TasksPatternsProcesses Landscape, Biotopes and Habitats Description of the environmental components and habitats Monitoring of major environmental events and their consequences on the cycles components Vector Bionomics and Competence Inventory, vectorial capacity and competence of vector populations Monitoring introduction, establishment and spread of vectors Public Health and Human Activities Public health demography of the human populations at risk Monitoring of significant population flows between and in countries Animal reservoirsEpidemiological inventory of the receptive wild and domestic animal populations Monitoring migrations (avifauna), movements and transport (livestock) of the animal reservoirs Study diseases using a common appraoch

10 PUB/HEALTH & SOCIO ECONOMY AGRO/ECOLOGY PATHOGENIC CYCLE Regional/local development Human activities economical / social conditions Landscapes Ecosystem Climate Vectors Pathogens hosts FOCI

11 EDEN work packages

12 Vertical Sub-Projects (SP) West Nile Virus Tick borne diseases Rodent borne diseases Malaria Leishmaniasis African Platform

13 and Horizontal Integration Teams (HIT) Disease Modelling LR Spatial Modelling Environmental Change Biodiversity Data Management West Nile Virus Tick borne diseases Rodent borne diseases Malaria Leishmaniasis African Platform

14 Ecosystem components studies WP1: Landscape, habitat, climate WP2: Vector WP3: Public Health WP4: Animal Reservoir PatternProcess PatternProcess PatternProcess PatternProcess West Nile Malaria Tick borne Rodent borne Leishmania Africa Platform WP5: Individual disease Data management & Modelling

15 Ecosystem components studies WP1: Landscape, habitat, climate WP2: Vector WP3: Public Health WP4: Animal Reservoir PatternProcess PatternProcess PatternProcess PatternProcess West Nile Malaria Tick borne Rodent borne Leishmania Africa Platform Disease transmission modelling Biodiversity Environmental change monitoring Low resolution spatial modelling Data management & information systems Horizontal integration WP5: Individual disease Data management & Modelling WP6 Horizontal activities WP6.1 Data management WP6.2 RS tools WP6.3 PhD program

16 Ecosystem components studies WP7 Overall Integration: Tools & scenarios Emergence & spread models WP1: Landscape, habitat, climate WP2: Vector WP3: Public Health WP4: Animal Reservoir PatternProcess PatternProcess PatternProcess PatternProcess West Nile Malaria Tick borne Rodent borne Leishmania Africa Platform Disease transmission modelling Biodiversity Environmental change monitoring Low resolution spatial modelling Data management & information systems Horizontal integration WP5: Individual disease Data management & Modelling WP6 Horizontal activities WP6.1 Data management WP6.2 RS tools WP6.3 PhD program

17 Ecosystem components studies WP7 Overall Integration: Tools & scenarios WP8: Training, Dissemination, Management & Coordination Emergence & spread models WP1: Landscape, habitat, climate WP2: Vector WP3: Public Health WP4: Animal Reservoir PatternProcess PatternProcess PatternProcess PatternProcess West Nile Malaria Tick borne Rodent borne Leishmania Africa Platform Disease transmission modelling Biodiversity Environmental change monitoring Low resolution spatial modelling Data management & information systems Horizontal integration WP5: Individual disease Data management & Modelling WP6 Horizontal activities WP6.1 Data management WP6.2 RS tools WP6.3 PhD program

18 EDEN strategy

19 HEALTH/ENVIRONMENT RESEARCH of model diseases in a variety of representative environmental settings Develop predictive emergence and spread models Catalogue of ecosystems and environmental conditions at risk: “emerging disease hot- spots” Develop early warning, surveillance and monitoring tools Contribute to decision support and policy making Identify factors triggering emergence and spread Characterise (new) transmission cycles Identify environmental changes likely to favour emergence TOOLS and POLICIES

20 HEALTH/ENVIRONMENT RESEARCH of model diseases in a variety of representative environmental settings Develop predictive emergence and spread models Catalogue of ecosystems and environmental conditions at risk: “emerging disease hot- spots” Develop early warning, surveillance and monitoring tools Contribute to decision support and policy making Identify factors triggering emergence and spread Characterise (new) transmission cycles Identify environmental changes likely to favour emergence TOOLS and POLICIES EDEN strategy document integrated ‘trans- disciplinary’ health/environment approach.

21 A key deiverable produced by the Steering Committee with back-up from the advisory group, specialists with internationally recognised skills in (i) biodiversity monitoring and assessment, (ii) environmental change detection, (iii) disease modelling, remote sensing, image processing and interpretation, and (iv) public health. The EDEN strategy document will propose an innovative integrated ‘trans-disciplinary’ health/environment approach for the unified analysis of the various EDEN outputs. The development of such an approach will be a major breakthrough of EDEN. EDEN strategy document

22 Objectives timeframe 12345 SD H&E T&P Dissemination SD: EDEN Strategy document H&E: Health/Environment research T&P: Tools and policies

23 Knowledge Flow integrated models health-environment DMEWS Disease Monitoring & Early Warning Systems External sources Advisory group Individual diseases models EDEN Indicator Diseases EDEN Steering Committee

24 Annex1, chap 4.1 Contribution to the objectives of the sub-priority “EDEN’s bold ambition is to enable a multi-DMEWS system on a solid scientific foundation running from the theoretical understanding of the reasons for the emergence of new diseases in vulnerable ecosystems, through an understanding of complex disease dynamics, to the practical application of such knowledge to disease control. We do not know the precise shape of this future yet: EDEN presents a chance to Europe to invest in some of the ‘brightest and best’ researchers to ensure success with this vision, and in doing so to advance significantly the state-of-the-art and put Europe firmly at the forefront of DMEWS.” Conclusion

25 EDEN management

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27 EDEN Coordinator EU Focal Point R. Lancelot - CIRAD Chairman SC D.J. Rogers Secretary SC G. Hendrickx Members Steering Committee Vertical Sub-projects EDEN-TBD: S. Randolph (UK) EDEN-Robo: H. Henttonen (Fin) EDEN-LEI: P. Ready (UK) EDEN-WNV: P. Reiter (Fr) EDEN-MAL: D. Fontenille (Fr) EDEN-AFR: Y. Thiongane (Sn) Horizontal Integration Teams Env. Changes: E. Lambin (Be) LRes. Mod: D. J. Rogers (UK) Data Mngt: W. Wint (UK) D. Modelling: H. Heesterbeek (Nd) Biodiv: JF. Guégan (Fr) PROJECT MANAGEMENT TEAM Financial Advisor Admin Assistant CIRAD support team ADVISORY GROUP Scientists, Users SCIENTIFIC ADVICE STEERING COMMITTEE Project Officer T. Karjalainen

28 EDEN Central management Day to Day EDEN Coordinator Integration Renaud Lancelot Chairman SC Scientific coordination David Rogers Secretary SC Operational Guy Hendrickx Secretariat Financial Olivier Pierre Administrative Sylvie Pugin CIRAD Technical inputs Secretariat Financial Olivier Pierre Administrative Sylvie Pugin CIRAD Technical inputs Solving EDEN’s problems

29 EDEN - Deputy SP Coordinators TBDKurt PfisterLudwig-Maximilians University – Munich, Germany (LMU) Milan LabudaSlovak Academy of Sciences - Bratislava, Slovakia (SAS) RoboHerwig LeirsUniversity of Antwerp – Antwerp, Belgium (UA) LEIMontserrat GallegoUniversity of Barcelona - Barcelona, Spain (UB) Robert FarkasSzent István University - Budapest, Hungary (SZIE) WNVZdenek HubalekAcademy of Sciences of the Czech Republic – Brno, Czech Republik (IVB) Alessandra della TorreUniversity of Rome ‘La Sapienza’ - Rome, Italy (UNISAP) MALRajae El AouadNational Institute of Hygiene - Rabat, Morocco (INH) Gabriella NicolescuNational Institute of Research and Development for Microbiology and Immunology “Cantacuzino” – Bucharest, Romania (NIRDMI) AFROuaffa Fassi FihriAgro-veterinary Institute – Rabat, Morocco (IAV) Jean-François MolezInstitut de Recherche pour le Développement – Dakar, Sénégal (IRD)

30 EDEN - Focal points TopicPersonAffiliation Gender equality and personnel interaction Sarah RandolphUniversity of Oxford, Oxford, UK Ethical aspects and safety rules of laboratory work Kurt PfisterLudwig-Maximilians University, Munich, Germany Ethical aspects of working with live animals Heikki HenttonenFinnish Forest Research Institute, Vantaa, Finland Gender action plan

31 EDEN – Advisory Group Duane GublerAsia-Pacific Institute of Tropical Medicine and Infectious Diseases, John A. Burns School of Medicine, Hawaii, USA Santiago Mas ComaPresident of the European Federation of Parasitologists (EFP), University of Valencia, Valencia, Spain Rainer SauerbornMedical Director of the Department of Tropical Hygiene and Public Health of the University of Heidelberg, Germany Graham WhiteMosquito & Fly Research Unit, Center for Medical, Agricultural & Veterinary Entomology, Gainesville, Florida, USA Philippe MartinPrincipal Administrator, European Commission, Directorate-General for Health and Consumer Protection, Risk Assessment (DG-SANCO) Bettina MenneSenior officer, Global Change and Health Program, World Health Organisation of the United Nations (WHO), Rome, Italy Jan SlingenberghSenior officer, Insect Pest Management, Food and Agriculture Organisation of the United Nations (FAO), Rome, Italy Antonio PetriniAnimal Health Information Department, World Organisation for Animal Health (OIE), Paris, France

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