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Modelling the conception to first birthday mortality curve Dr Paul Williamson & Prof. Bob Woods Department of Geography Workshop on Fetal and Infant Survival.

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Presentation on theme: "Modelling the conception to first birthday mortality curve Dr Paul Williamson & Prof. Bob Woods Department of Geography Workshop on Fetal and Infant Survival."— Presentation transcript:

1 Modelling the conception to first birthday mortality curve Dr Paul Williamson & Prof. Bob Woods Department of Geography Workshop on Fetal and Infant Survival

2 0 100 200 300 400 500 600 0200400600 Days after LMP Dying out of 1000 conceptions 450 475 500 525 550 575 600 Dying out of 1000 conceptions

3 Embryo: 14-41 days after LMPEarly fetal: 42-195 days after LMPLate fetal (stillbirths): 196-279 days after LMPEarly neonatal: 280-286 days after LMPLate neonatal: 287-307 days after LMPPost neonatal: 308-644 days after LMP

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6 Where y^ = predicted fetal-infant loss per 1000 conceptions x = days after LMP y o = 473.3523x o = 280 A = -2549.0207B = 0.1197C = 28.9374D = 6.8747 E = 1.1418F = 84.4912G = 154.719H = 11.1787

7 a) Component 1embryonic and early fetal loss [14-196 days after LMP] [Exponential growth curve]

8 b) Component 2late fetal and neonatal [196-308 days after LMP] [Aysmmetrical sigmoidal (4 params.)]

9 c) Component 3 post-neonatal [308-644 days after LMP] [Asymmetrical sigmoidal (3 params.)]


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