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Ion Channels. Cell membrane Voltage-gated Ion Channels voltage-gated because they open and close depending on the electrical potential across the membrane.

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Presentation on theme: "Ion Channels. Cell membrane Voltage-gated Ion Channels voltage-gated because they open and close depending on the electrical potential across the membrane."— Presentation transcript:

1 Ion Channels

2 Cell membrane

3 Voltage-gated Ion Channels voltage-gated because they open and close depending on the electrical potential across the membrane.

4 Chemically-gated Ion Channels Ligand-gated ion channels G-protein coupled receptors

5 Membrane potential

6 Subunit structure of the voltage-gated sodium channels

7 Amino acid sequence similarity and phylogenetic relationships of voltage-gated sodium channel  subunits The nine sodium channel isoforms may be considered members of one protein family.

8 RECEPTOR DATABASE http://www.iuphar-db.org/GPCR/index.html


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