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Puberty Is the period which links the childhood and adulthood
Female Pubertal Developments Period: 4-5 years (1.5-6 years)
Female Pubertal Sequences: Growth 9.8 years Thelarche 10.0 years Adrenarche 10.5 years Menarche 12.8 years
Time of Puberty Family Sex Nutrition Obesity Psychological Genetic General health Geographical location Exposure to the light
Physiology of the female puberty Hormonal & physical changes
I- During childhood Low levels of hormones (gonadostat): GnRH FSH&LH Estrogen
Suppression of the Activity Levels of Hormones Hypersensitivity of the Hypothalamus Intrinsic CNS inhibition
II- During Adolescence Increase levels of hormones: Adrenal androgen (Adrenarche) Gonadotrophic hormones (FSH&LH) Estrogen (Gonadarche)
High Activity Levels of Hormones Decrease sensitivity Maturation of Hypothalamus Increase amplitude & frequency of pulsative GnRH
The Release of Pulsative GnRH Increase Gonadotrophic & steroids Appearance of secondary sexual characteristics Menarche Ovulation (estradiol-LH)
Secondary Sexual Characteristics: Breast development Pubic and axillary hair growth Female fate distribution Vaginal and uterine growth Skeletal growth
Growth Growth spurt, express as increase linear growth velocity in cm per year.
Growth Peak: 2 years after breast budding Height: reached maximum at age 17-18 years Skeletal changes: * Insulin-like GF * Growth hormone * Sex steroid
Thelarche The earliest sign of of puberty to become evident is usually breast growth
Adrenarche The growth of pubic and axillary hair is due to increase production of adrenal androgen
Adrenarche Increase androgen: 6-15 years Is not under control of the following: * Gonadotrophin * ACTH * Prolactin
Tanner Staging The breasts and of pubic hair growth of puberty have been classified into five stages
Gonadarche Factors which induce gonadarche in late pre-puberty: * Anterior pituitary response GnRH * Follicle reactivity to FSH&LH
The Age of Menarche is decline: Improve nutritional status Body weight (47.8 kg) Percentage of fat (16-23%) Obese girls (23-30%)
In summary Puberty Increase levels of gonadotrophins&steroids Appearance of secondary sexual characteristics Pulsatile GnRH (10-16 years) Central negative inhibition Maturation of positive feedback
Puberty Female Maturational Changes Male Maturational Changes
Pubertal Processes What biological changes of puberty have the biggest impact on boys or girls? What teens worry about? What teens talk about? What teens.
Puberty and associated changes
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MCB 135E Discussion GSI: Jason Lowry Nov 29 – Dec 3.
Adolescence and Puberty
Biological Foundations: Puberty How to cope with others’ responses; How to deal with sexual arousal; Puberty is the key developmental challenge in adolescence.
Lecture outline I. Puberty & Development of Secondary Sexual Characteristics A. Establishing the ovarian cycle B. Breast development C. Pubic and Axillary.
Growth and Development 1 PUBERTY Viv Rolfe. Discuss the age of onset of puberty in males and females Development of secondary sexual characteristics at.
ENDOCRINE PROJECT By: Katie Glaeser Melanie Olmedo 8 th January 13, 2014.
PUBERTAL DEVELOPMENT Dr Assunta Albanese St George’s Hospital London.
NORMAL PUBERTAL DEVELOPMENT
Department of Physiology
Growth and Development
Dr Olcay Evliyaoğlu Pediatric Endocrinology Department
Obstetrics & Gynecology Week 1 Female anatomy, normal menstrual cycle.
Chapter 2. REPRODUCTIVE CHANGES IN THE FEMALE LIFESPAN
Normal puberty Dr Neda Mostoufizadeh Pediatric Endocrinologist.
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