1. Copyright © 2004 by Limsoon Wong Research & Discovery: Technologies Today for Solving Problems Tomorrow Limsoon Wong Institute for Infocomm Research

2. Copyright © 2004 by Limsoon Wong Plan Making Research Exciting –Have long-term vision –Knowing what counts Looking for Emerging Opportunities –Misconceptions –Advice for increasing probability of success –Sources of opportunity for innovation A role model Reasons for Optimism in R&D

3. Copyright © 2004 by Limsoon Wong Making Research Exciting

4. Copyright © 2004 by Limsoon Wong Have Long-Term Vision By 2010, quality of life will be improved by an ICT technology-based product of ours By 2015, at least one Singapore company will become a successful MNC based on our technology-based product

5. Copyright © 2004 by Limsoon Wong What Really Counts…10X Impact Good (practical) research should have a story like this at the end –produced a technology used by millions –produced a technology earning millions of dollars –produced a technology that makes a difference to the Singapore ICT industry –first to identify an important problem and solve it –first to solve an important existing problem –make a 10x improvement to the solution of an existing problem

6. muvee Technologies’ Automatic Video Production Software Adopted by Sony’s Digital Imaging Devices muvee’s pioneering technology will dramatically simplify creative photo and video production for millions of consumers.

7. Toppan has developed an original RFID chip, and peripheral devices, including tags and reader/writers, through collaboration with I2R Annual sales of the system in Japan will reach 2 billion yen (S$31M) in 2005

8. Some speculative tech for transforming sports editorial content production industry 30% 18% Enhanced Tennis TV

9. Vaccines are often the only solution for viral diseases Finding & developing effective vaccine targets (epitopes) is slow and expensive process

10. Enabled MOM’s Occupational Hazards Dept to automate checking chemical safety info from Material Safety Data Sheets and verifying standards conformance

11. Copyright © 2004 by Limsoon Wong Looking for Opportunity

12. Copyright © 2004 by Limsoon Wong Misconceptions Innovation must big Innovations are the works of geniuses Innovations depend on novel ideas Innovations occur only in commercial markets

15. Copyright © 2004 by Limsoon Wong Practical Advice to Increase Probability of 10X Look for a clear need where –solution is not expected for several years –not at a big disadvantage to arrive before competition –have or can build strength –partner to move ahead faster in a win-win way In short, start from our strongest point, target for maximum impact, and attack competitor's weakest point. Also collaborate to gain advantage over "us"-only effort

16. Copyright © 2004 by Limsoon Wong Practical Advice to Increase Probability of 10X Carry out what we set out to do Improve quality & rigor of our work Improve quality & passion of our people Evangelize our ideas & projects to the world

17. Copyright © 2004 by Limsoon Wong Sources of Opportunity for Innovation Unexpected success/failure in our work & outside event Gap betw reality & common belief Bottleneck in processes Change of industry struct---new biz model, distribution channels, modes of business, etc. Change in demographics---age, religion, income, etc. Change of mood & perception---terrorism, fashion, etc. Fringe practices that may solve persistence breakdown in current central practices, ie. value innovation New knowledge & scientific advances Man-made barriers--- legislation & regulation

18. Copyright © 2004 by Limsoon Wong A Role Model: Li Jinyan

19. Copyright © 2004 by Limsoon Wong Jinyan’s Vision No human will fall sick unexpectedly No machine will fail unexpectedly

20. Copyright © 2004 by Limsoon Wong Jinyan’s Aim for 10X Diagnosis of diseases and optimization of treatments  sufferings are reduced and chance of cure is increased Prediction of faults in engineering systems and optimization of industrial systems  safety is improved, cost is reduced, and quality is raised Analysis of computer and network logs to detect intrusion and other threats  cyber struct is strengthened, and assets are guarded

21. Childhood ALL Major subtypes: T-ALL, E2A-PBX, TEL-AML, BCR-ABL, MLL genome rearrangements, Hyperdiploid>50, Diff subtypes respond differently to same Tx Over-intensive Tx –Development of secondary cancers –Reduction of IQ Under-intensiveTx –Relapse The subtypes look similar Conventional diagnosis –Immunophenotyping –Cytogenetics –Molecular diagnostics Unavailable in most ASEAN countries Copyright © 2004 by Limsoon Wong

22. Single-Test Platform of Microarray & Knowledge Discovery training data collection feature selection Image credit: Affymetrix feature generation feature integration

23. Conventional Tx: intermediate intensity to all  10% suffers relapse  50% suffers side effects  costs US$150m/yr Jinyan’s optimized Tx: high intensity to 10% intermediate intensity to 40% low intensity to 50% costs US$100m/yr Copyright © 2004 by Limsoon Wong High cure rate of 80% Less relapse Less side effects Save US$51.6m/yr Impact

24. An Important Ingredient in Jinyan’s Success: Collaborations Copyright © 2004 by Limsoon Wong He does the wet expts He invents the algo’s She implements the algo’s He designs the dry expts & interprets betw the dry & wet

25. Copyright © 2004 by Limsoon Wong Reasons for Optimism in ICT R&D

26. Copyright © 2004 by Limsoon Wong High-Level Drivers Physical needs –nourishment, –health,... Security needs –privacy –protection –stability –ownership Socializing needs –collaboration –sharing –be understood –be informed Entertainment needs –novelty –belonging –communicating –mobility

27. Copyright © 2004 by Limsoon Wong Major Trends The use of info mgmt & tech has become more complex more “self-service” more personalization more embedded more distributed more pervasive

28. Copyright © 2004 by Limsoon Wong Major Apps “Trans-disciplinary” Apps –Lifestyle & entertainment organizing data, narrowing human-digital, virtual gaming, realistic immersive user experience, entertainment on demand, digital rights, asset mgmt, IP protection,... –Tech in healthcare pervasive digital media, adaptive syst, decision syst, … –Ubiquitous systems privacy, security, monitoring of trans, image processing, lang translation, voice recognition, adaptive syst, decision syst –Smart sensors & intelligent syst signal processing, pattern recognition, security, privacy, adaptive syst, decision syst,... –Physical & digital security privacy, surveillance, authentication, access control, audit, behaviour analysis, abnormal event diagnostic, multimedia crytographic algo,... “Traditional” Apps –E-learning –E-govt –E-health –E-traffic –EAI –SCM –PDA –Knowledge mgmt,...

29. Copyright © 2004 by Limsoon Wong Engines of Growth Business intelligence –ontology & metadata tech –adaptive tech –human language tech –collaboration tech –decision tech Information security –security infrastructure –cyber terrorism –biometrics tech –privacy & identity mgmt Native media processing & analysis –production tech –analysis tech –distribution tech –intuitive user interfaces

30. Enabled by Info Mgmt Engg Sci in Medicine Int Syst & Sensor Networks Env Tech Integrative Manufact Broad Band Grid protect video, audio, & image analysis decision tech Energy

31. Copyright © 2004 by Limsoon Wong Thank You

32. Copyright © 2004 by Limsoon Wong Pre-Horizon 2004 Seminar 1st Nov 2004 2:15pm-2:45pm BIG ONE