1. KINGDOM OF CAMBODIA Ministry of Health National Center for Parasitology, Entomology and Malaria Control CNM

2. National anti-malaria drug policy Create and maintain access to early diagnosis and prompt, effective, safe and good quality treatment of malaria disease. Minimize selection pressure for drug resistance.

3. Parasitological cure to reduce reservoir of infection. The anti-malaria drug use was based on the National treatment guideline for Malaria and recommended by WHO.

4. Anti-malaria drug combination National Treatment Guideline for Malaria - National treatment Guideline was developed in 2000 (for combination therapy) - Artesunate and Mefloquine combination for first line treatment - Quinine with Tetracycline for second line treatment

5. Anti-malaria drug procurement Plan MoH procurement (National budget and WB) CNM procurement (Global Fund)

6. A+M blister packaging Facility Packaging facility was agreed by MoH to setting up this facility The blister packaging process was supported by WHO and supervised by CNM (National Malaria Center) Artesuante and Mefloquine free tablets were supplied by MoH (CMS) to the packaging facility

7. A+Ms Categories There are 3 categories of A+M: A+M2 = 6 tablets of Artesunate and 2 tablets of Mefloquine A+M3 = 9 tablets of Artesunate and 3 tablets of Mefloquine A+M4 = 12 tablets of Artesunate and 4 tablets of Mefloquine

8. Quality Assurance Before packaging All of batch number of Artesunate were analyzed All of batch number of Mefloquine were analyzed After packaging All of lot number of each A+M categories were analyzed Stability of all A+M categories were done At the field 2 sides were selected for collecting the A+M 3 monthly for collecting the A+M from all fields

9. Anti-malaria drug supply system The A+Ms were supplied through the public sector The Malarine ® were supplied through the PSI organization to the Private sector

10. ANTI-MALARIA DRUG SUPLLY SYSTEM IN CAMBODIA DEPARTMENT OF DRUG AND FOOD ESSENTIAL MEDICINE BUREAU CENTRAL MEDICAL STORE NATIONAL HOSPITAL=7NHs PROVINCIAL HEALTH DEPARTMENT OPERATIOAN DISTRICT = 75ODs OFFICE AND PHARMACY REFERRAL HOSPITAL 68RHs HEALTH CENTER 827HCs HEALTH POST REPORT SUPPLY REPORT and SUPPLY TEMPORERY TIME Outreach Activity MINISTRY OF HEALTH

11. Anti-Malaria drug monitoring Drug regulation Efficient procurement Efficient distribution Drug efficacy Drug quality Drug use practices