1. Ruth M. Saecker and M. Thomas Record, Jr Current Opinion in Structural Biology Volume 12, Issue 3, 1 June 2002, Pages 311-319

2. Figure 14.07c: Diagram of lac operon in induced state

3. Figure 14.12: The three lac operators.

4. Table 14.T02: Characteristics of Partial Diploids Having Various Combinations of lacl and lacO Alleles

5. Figure 14.19: DNA looping to permit Lac repressor to bind to two operators Tropp: Adapted from Müller-Hill, B., Curr. Opin. Microbiol. 1 (1998): 145-151. Ruth M. Saecker and M. Thomas Record, Jr Current Opinion in Structural Biology Volume 12, Issue 3, 1 June 2002, Pages 311-319

6. Figure 14.13: A view of the lac repressor monomer from the complex with DNA. Protein Data Bank ID: 1LBG. Lewis, M., et al., Science 271 (1996): 1247-1254. Structure rendered by Hongli Zhan and provided by Kathleen S. Matthews, Rice University.

7. Figure 14.14: A complex of Lac repressor N-terminal domain ("headpiece") with an 11 bp half-operator corresponding to the left half of wild-type lac operator Protein Data Bank ID: 1LCC. Chuprina, V. P., et al., J. Mol. Biol. 234 (1993): 446-462.

8. Figure 14.11: Thirty-five base pairs protected by the lac operator.

9. Figure 14.15: Structure of dimeric Lac repressor created by recombinant DNA techniques so that the carboxyl terminal domains are missing. Protein Data Bank ID: 1EFA. Bell, C. E., and Leweis, M., Nat. Struct. Biol. 7 (2000): 209-214.

10. Figure 14.16: Effects of isopropylthiogalactoside (IPTG) on the Lac repressor structure. Reproduced from Biochemistry, Fifth Edition, by Jeremy M. Berg, et al. © 2002 by W. H. Freeman and Company. Used with permission.

11. Figure 14.18a: Model showing the reactions that are elicited when IPTG binds to the Lac repressor. Adapted from Matthews, K. S., Falcon, C. M., and Swint-Kruse, L., Nat. Struct. Biol. 7 (2000): 184-187.

12. Figure 14.18b: ITPG bound to lac repressor Adapted from Matthews, K. S., Falcon, C. M., and Swint-Kruse, L., Nat. Struct. Biol. 7 (2000): 184-187.

13. Figure 14.17: Crystal structure of Lac repressor bound to DNA. Protein Data Bank ID: 1LBG. Lewis, M.,, et al., Science 271 (1996): 1247-1254.

14. Table 14.T03: Demonstration of Repressor-Operator Binding by the Filter- Binding Assay

15. Mark M. Levandoski, Oleg V. Tsodikov, Diane E. Frank, Sonya E. Melcher, Ruth M. Saecker and Thomas M. Record Jr Journal of Molecular Biology Volume 260, Issue 5, 2 August 1996, Pages 697- 717

16. Figure 2. Effects of salt concentration on the formation of 1:1 LacI:Osym complex (TO). Open and filled symbols represent previously reported and new data (see Table 2), respectively. Circles represent values of KobsTO of binding of 2514 bp OsymDNA, triangles are values of KobsTO for 101 bp DNA, squares are values of KobsTO for 40 bp DNA. The values of the binding constants are obtained from global analysis of titration data as described in the text. The points with upward arrows correspond to lower bound values of KobsTO. Oleg V. Tsodikov, Ruth M. Saecker, Sonya E. Melcher, Mark M. Levandoski, Diane E. Frank, Michael W. Capp and M. Thomas Record, Jr Journal of Molecular Biology Volume 294, Issue 3, 3 December 1999, Pages 639-655

18. Ruth M. Saecker and M. Thomas Record, Jr Current Opinion in Structural Biology Volume 12, Issue 3, 1 June 2002, Pages 311-319