1. U.S. Bone Growth and Spinal Fusion Stimulator Markets Rapid Growth in Stimulator Market in Recent Years Driven by Quest for Less-invasive Treatment Options “Physicians are exhibiting a renewed interest in bone growth and spinal fusion stimulators due to better product designs, stronger reimbursement, and the desire for adjunctive treatments that improve the success of spinal fusions and the healing of difficult fractures." Medical Devices Analyst Team Frost & Sullivan

2. Development of biologic treatments overlaps with stimulation providing opportunities and threats New applications of PEMF technology allow manufacturers to leverage it into new markets Application of stimulators to cervical spinal fusion holds significant revenue potential Increasing number of spinal fusion procedures boosts sales of spinal fusion stimulators Better stimulator designs improve patient compliance and therapeutic benefits leading to increased market revenues Industry Trends

3. New distribution agreements with top orthopedic companies fuel expansion of stimulator market revenues Swelling population of older Americans leads to increased need for stimulation Growing number of spinal surgeons practicing, boosts equipment sales Increased use of instrumentation in trauma fixation and spinal fusion surgery leads to improved success rates without stimulators limiting market revenues Industry Trends (cont’d)

4. Frost & Sullivan provides: Detailed insights into recent developments and trends Drivers, restraints, challenges, and strategic recommendations Analyst insights on ‘hot topics” and emerging applications in the Bone Growth and Spinal Fusion Stimulator Market Market sizing and competitive analysis Market forecasts and opportunity analysis Detailed revenue breakdowns for both bone growth and spinal fusion stimulators in both external and implantable designs Detailed discussion of emerging applications for PEMF technology and stimulation synergies with orthobiologics Key Features

5. Coverage of United States market which generates the vast majority of revenues in the bone growth and spinal fusion stimulator market Proven methodology encompassing extensive primary and secondary data and research Focused information and strategies that cover business and technology issues Credible data and analysis highlighting industry dynamics Winning strategies to help you create precise business plans What We Offer

6. Current Market Participants Accurate third-party assessment of market for use in business planning Assess current and future drivers and restraints Determine and exploit new application opportunities Find detailed, market sizing numbers for your own planning needs New Entrants Analyze challenges associated with the industry Learn about winning strategies used by existing competitors Position yourself to capitalize on the market’s unmet needs Third-party market estimations for use in business plans Investment Community Analyze long-term strategies of companies selling stimulators Determine which participants will outperform the competition Assess attractiveness of investing in market Who Will Benefit?

7. What’s Included Bone Growth StimulatorsSpinal Fusion Stimulators Implantable External PEMF/CMFPEMF/CMF/US Capacitative Coupling

8. BREG, Inc. (Distributor) dj Orthopedics, Inc. (Planning to be Distributor in 2003) DePuy Acromed, Inc./ Johnson & Johnson EBI Medical Systems, Inc./ Biomet, Inc. Medtronic Sofamor Danek/ Medtronic, Inc. (Distributor) Orthofix, Inc. OrthoLogic Corp. Smith & Nephew Plc Orthopaedics – Exogen Key Market Participants

9. Call toll free 877 G O F ROST (877.463.7876) Fax toll free 888.690.3329 Email myfrost@frost.com Visit www.frost.com For More Information