Download presentation

1
**Analysis of Human EEG Data**

Pavel Stránský Supervisor: Prof. RNDr. Petr Šeba, DrSc.

2
**Content Measurement and structure of EEG signal**

EEG as a multivariate time series, statistical approach to EEG data processing Small introduction to random matrices theory My present results and outlook

3
**Measurement and Structure of EEG Signal**

1 Measurement and Structure of EEG Signal

4
**1. Measurement and Structure of EEG Signal**

Cerebral Electric Activity EEG = Electro-encephalography, Electro-encephalogram

5
**1. Measurement and Structure of EEG Signal**

Location of the Electrodes (10-20 system, 21 electrodes)

6
**1. Measurement and Structure of EEG Signal**

An Example of EEG Measurement Alpha waves Beta, theta, delta waves Other graphoelements Artefacts

7
**Statistical Approach to EEG Data**

2. Statistical Approach to EEG Data

8
**2. Statistical Approach to EEG Data**

Modelling and processing time series Vector Autoregression VAR(p) Stacionarity (Covariance – stacionarity): for all t and any j White noise: for all t, t1, t2

9
**2. Statistical Approach to EEG Data**

Modelling and processing time series (cont.) Other ways of treating with time series: Principal component analysis Independent component analysis Testing for periodicity (Fisher’s test, Siegel’s test) mixing ICA

10
**3. Small introduction to random matrix theory (RMT)**

11
**3. Small introduction to RMT**

Random matrices Study of excitation spectra of compound nuclei The same behaviour like eigenvalues of random matrices 3 principal ensembles: GOE, GUE, GSE Hermitian self-dual matrices, symplectic transformations Hermitian matrices, unitary transformations Def: Gaussian othogonal ensemble is defined in the space of real symmetric matrices by two requirements: 1. Invariance (O is orthogonal matrix) 2. Elements are statistically independent which means that , where (probablity density function)

12
**3. Small introduction to RMT**

Random matrices (cont.) Universality classes: GUE Hamiltonians without time reversal symmetry GOE Hamiltonians with time reversal symmetry and WITHOUT spin-1/2 interactions GSE Hamiltonians with time reversal symmetry and WITH spin-1/2 interactions Universal law for joint probability density function: For energies x(eigenvalues of H) b = 1 GOE b = 2 GUE b = 4 GSE

13
**3. Little introduction to RMT**

Random matrices (cont.) Spectral correlations (nearest neighbour spacing distribution): Wigner distribution Normalization

14
**3. Little introduction to RMT**

Random matrices (cont.) Other distributions (taking into account correlations for longer distances) S2 statistics (number variance) D3 statistics (spectral rigidity)

15
4. Results, outlook

16
**Correlation analysis of EEG Data**

4. Results, outlook Correlation analysis of EEG Data Dividing EEG signal from M channels x1, ..., xM into cells of constant time length T Computing correlation matrix Cm for the mth cell with normalizing mean and variance: Finding eigenvalues xm of all correlation matrices Cm

17
**Correlation analysis (cont.)**

4. Results, outlook Correlation analysis (cont.) Unfolding the spectra: (after unfolding all eigenvalues are "equally important", the resulting eigenvalue density r(x) is constant) Finding nearest neighbour distribution p(s) for the unfolded spectra:

18
**Correlation analysis (cont.)**

4. Results, outlook Correlation analysis (cont.) Comparing computed spacing distribution with theoretical Wigner curve

19
**Outlook 4. Results, outlook**

Use more subtle method from RMT and time series analysis to analyze the correlations and also autocorrelations (correlations in time) Find significant and reproducible variables for standard EEG measured on healthy subjects Deviations are expected if there was some neural disease

20
**Literature 4. Results, outlook**

P. Šeba, Random Matrix Analysis of Human EEG Data, Phys. Rev. Lett. 91, (2003) T. Guhr, A. Müller-Groeling, H. A. Weidenmüller, Random Matrix Theories in Quantum Physics: Common Concepts, Phys. Rep. 299, 189 (1998) M. L. Mehta, Random Matrices and the Statistical Theory of Energy Levels, Academic Press (1967) H. J. Stöckmann, Quantum Chaos: An Introduction, Cambridge University Press (1999) A. F. Siegel, Testing for Periodicity in a Time Series, JASA 75, 345 (1980) J. D. Hamilton, Time Series Analysis, Princeton University Press (1994) A. Jung, Statistical Analysis of Biomedical Data, Dissertation, Universität Regensburg (2003) J. Faber, Elektroencefalografie a psychofyziologie, ISV nakladatelství Praha (2001)

Similar presentations

OK

Lecture 3 BME452 Biomedical Signal Processing 2013 (copyright Ali Işın, 2013) 1 BME452 Biomedical Signal Processing Lecture 3 Signal conditioning.

Lecture 3 BME452 Biomedical Signal Processing 2013 (copyright Ali Işın, 2013) 1 BME452 Biomedical Signal Processing Lecture 3 Signal conditioning.

© 2017 SlidePlayer.com Inc.

All rights reserved.

Ads by Google

Ppt on water softening techniques hair Ppt on content development tools Ppt on x ray film processing Ppt on channels of distribution in china Ppt on revolution of the earth and seasons video Ppt on regional trade agreements signed Ppt on wild animals for grade 1 Ppt on applied operational research notes Ppt on conservation and management of forest Ppt on addition for class 3