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TrueRaphe’d Bicuspid aortic valve (BAV) repair with valve-sparing root replacement (VSRR): the state-of-the-art? Thomas G. Gleason, M.D., Forozan Navid, M.D., Wilson Szeto, M.D., Joseph E. Bavaria, M.D. University of Pittsburgh and University of Pennsylvania
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True BAV with insufficiency Raphe’d BAV with stenosis Variable morphological and clinical phenotypes dictate candidacy for preservation
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Valve-sparing Root Replacement: Modified Reimplantation Technique Gleason, JTCVS 2005;130:601-3.
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Valve repair & reimplantation: MRA depicts neosinus creation TricuspidRepaired bicuspid (true) Repaired bicupsid (raphe)
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Aortic valve repair maneuvers used Central or commissural cusp plication Central or commissural cusp plication Cusp resections (triangular) Cusp resections (triangular) Pericardial patch-leaflet replacement Pericardial patch-leaflet replacement Commissuroplasty Commissuroplasty Leading edge reinforcement/shortening Leading edge reinforcement/shortening Rudimentary commissural release Rudimentary commissural release Annuloplasty Annuloplasty
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Circulation 2007;116 [suppl I]:I-264-69.
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Post AV repair (triangular resection, commissuroplasty), root replacement, valve reimplantation. Triangular resection Commissuroplasty
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Post-repair (triangular resection)
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2 VSRR techniques used U Pitt 15 cases all using modified reimplantation technique (tailored graft) (Gleason Root graft sizes 36-42 mm U Pitt 15 cases all using modified reimplantation technique (tailored graft) (Gleason JTCVS 2005;130:601-3.) Root graft sizes 36-42 mm Final internal annular diameter 26.5-31 mm Final internal annular diameter 26.5-31 mm 4 pleats used to create 2 sinuses 4 pleats used to create 2 sinuses 20-26 annular sutures used for annuloplasty 20-26 annular sutures used for annuloplasty Mean cusp depth 19.4 mm Mean cusp depth 19.4 mm 2-7 leaflet maneuvers/case (mean 4/case) 2-7 leaflet maneuvers/case (mean 4/case) HUP 8 cases all using commercial “Valsalva graft” (Cameron Ann Thorac Surg 2006;82:548-53.)
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Demographics: 23 patients Mean age 45.5 (range 33-66) Mean age 45.5 (range 33-66) 19 male 19 male Procedures performed in all 23 patients: Procedures performed in all 23 patients: VSRR 23 VSRR 23 Complex AV repair 8 Complex AV repair 8 Annuloplasty 15 Annuloplasty 15 Hemiarch replacement 21 Hemiarch replacement 21 Cox-maze III 1 Cox-maze III 1 Max aortic orthogonal diameter 53.7 mm (range 48-65mm) Max aortic orthogonal diameter 53.7 mm (range 48-65mm) Aortic regurgitation Aortic regurgitation 0-trace: 5 pts. 0-trace: 5 pts. 1+ : 8 pts. 1+ : 8 pts. 2+ : 3 pts. 2+ : 3 pts. 3+ : 4 pts. 3+ : 4 pts. 4+ : 3 pts. 4+ : 3 pts.
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Bicuspid aortic valve repair & reimplantation with VSRR 23 VSRR for BAV and TAA 23 VSRR for BAV and TAA 8 with AV repair 8 with AV repair 15 without AV repair 15 without AV repair 7 true BAV 7 true BAV 16 BAV with raphe 16 BAV with raphe Follow-up (2-68 mos, mean 34 ±4 mos) Follow-up (2-68 mos, mean 34 ±4 mos) 0% mortality 0% mortality 0% stroke 0% stroke 0% PPMs 0% PPMs 0% reoperations 0% reoperations 100% freedom from ≥ 2+ AR 100% freedom from ≥ 2+ AR 8.6% 1+ AR 8.6% 1+ AR 91% 0-trace AR 91% 0-trace AR
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Assessment for aortic valve repair/VSRR A.A good repair is better than a good (bio)prosthesis i.No anticoagulation ii.Potential for longer (indefinite) durability iii.Potential for better hemodynamic profile B.Pitfalls i.Patient selection ii.Understanding the “pathodynamics” of the valve iii.Technically more difficult
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