2. 1 1 Mitosis Mitosis is the process in which the nucleus divides to form two new nuclei. What disease is mitosis gone wild?

9. 8 8 CANCER In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body.

10.  Video Video  Video 2 Video 2

11. How do little elephants grow up to be BIG elephants?

13. Your life begins after a sperm fertilizes an egg, and you are smaller than a period in a newspaper.

20. Animal Mitosis -- preview Interphase Prophase Metaphase Anaphase Telophase Cytokineses

21. Animated Mitosis Cycle http://www.cellsalive.com/mitosis.htm Interphase Prophase Metaphase Anaphase Telophase Cytokinesis

22. Chromosomes are replicated (amount of DNA doubles) Chromosomes appear as threadlike coils ( chromatin ) CELL MEMBRANE Nucleus Cytoplasm

23. Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm

24. Chromatin condenses into chromosomes Centrioles (or poles) appear and begin to move to opposite end of the cell of animal cells. Spindle fibers form from centrioles. Centrioles Sister chromatids Spindle fibers

25. Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm Spindle fibers

26. Chromosomes line up along the metaphase plate Spindle fibers attach to the centromeres of each chromosome Centrioles Spindle fibers

27. Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm

28. Sister chromatids pulled apart by shortening spindle fibers. Centrioles Spindle fibers

29. Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm

30. Nuclear membranes form around chromosomes. Mitosis ends. Nuclei Chromatin

31. Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm

32. Cell membrane moves inward to create two daughter cells – each with its own nucleus with identical chromosomes.

33. Plant Mitosis -- Review Interphase Prophase Metaphase Anaphase Telophase Cytokinesis

34.  I  I nterphase  P  P rophase  M  M etaphase  A  A naphase  T  T elophase  C  C ytokinesis IPMATC I Pay M oney At T he Cashier

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37. Confused? Here are links to fun resources that further explain mitosis:  Mitosis Main Page on the Virtual Cell Biology Classroom of Science Prof Online. Mitosis Science Prof Online  “Imitosis” music video by Andrew Bird. “Imitosis”  DNA Replication step-through animation by John Kyrk. DNA Replication  Mitosis & Cytokinesis animated video by McGraw-Hill. Mitosis & Cytokinesis  Mitosis animation, step-through and quiz, Sadava, et al., Life: The Science of Biology, 9th Edition, Sinauer Associates. Mitosis  Mitosis step through animation from CellsAlive.com. Mitosis  “That Spells DNA” song by Jonathan Coulton. “That Spells DNA” (You must be in PPT slideshow view to click on links.) From the Virtual Cell Biology Classroom on ScienceProfOnline.comVirtual Cell Biology ClassroomScienceProfOnline.com