1. Structure of ArboNET and summary of West Nile Virus Activity The Arbonet Team Division of Vector-Borne Infectious Diseases Centers for Disease Control & Prevention Fort Collins, Colorado Chet Moore Colorado State University Fort Collins, CO

2. ArboNET Database “Users don’t know what they really want, but they know for certain what they don’t want." Manubay’s Laws for Programmers Keep it simple – avoid complex and multi-layered data entry screens whenever possible Build data entry screens to work the way data entry clerks actually enter the data Where possible, build compatibility with other data collection systems (e.g., NEDSS, etc.)

3. Use drop-down lists, auto-fill and other time savers whenever possible (automatically calculate totals, statistics, etc.) Build error checking routines into the software Use lists to prevent spelling errors and similar problems "Never attribute to malice that which is adequately explained by incompetence." Hanlon's Razor

5. Historical Perspective Progression of West Nile Virus Activity in the United States, 1999-2005

6. 1999

7. 2000

8. 2001

9. 2002

10. 2003

11. 2004

12. 2005

13. CategoryNo. Tested**No. PositiveNo. States Mosquito12.8 million36,28848 † Dead bird128,48653,38148 † VeterinaryUnavailable23,44747 ‡ HumanUnavailable19,70646 † Sentinel chicken/ horse Unavailable7,15430 ‡ WNV Surveillance Totals, US, 1999-2005* * Reported as of 5/5/2006 ** Excludes 1999 † Plus DC ‡ Plus Puerto Rico

14. Observed & Predicted WNV Events, 2000 AugSep Oct JulJun AprMay Viral activity (inferred) Crow, Suffolk Oc. japonicus, Westchester; Cx. pipiens, Richmond Horse, Richmond Human, Richmond Sentinel Chicken, Westchester Crow, Richmond Sentinel wild bird, Suffolk Human Horse Mosquito Crow Sentinels Predicted Observed

15. Innovative Vector Control Consortium (IVCC) Dengue Decision Support System Liverpool School of Tropical Medicine Colorado State University University of California, Davis South African Medical Research Council Funded by Bill and Melinda Gates Foundation

16. A possible scheme of software and data organization for the Dengue Decision Support System (DDSS) Data sent Data/maps retrieved Map server/GIS Web server (Central site; CSU) Non-spatial statistics software (R) Spatial analysis software (ArcGIS, SIG Epi, R) Dengue model Other resources Reprint database Guidelines & SOP’s Links to other sites Other data sets DEN seroprevalence Insecticide resistance Ae. aegypti density Dengue databases Other data layers Land use/land cover Hydrology Streets/roads Spatial data layers End users (Field sites, national programs) Low-cost software (SIG Epi) Database GIS Statistics

19. WNND County Level Incidence per Million, United States, 2002 Incidence per million.01-9.99 10-99.99>=100 Any WNV Activity

20. WNND County Level Incidence per Million, United States, 2003 Incidence per million.01-9.99 10-99.99>=100 Any WNV Activity

21. WNND County Level Incidence per Million, United States, 2004 Incidence per million.01-9.99 10-99.99>=100 Any WNV Activity

22. WNND County Level Incidence per Million, United States, 2005* Reported as of 5/5/2006 Incidence per million.01-9.99 10-99.99>=100 Any WNV Activity

23. Human WNV Disease Cases, by Age Group and Clinical Category, United States, 2005* * Reported as of 5/5/2006

24. West Nile virus neuroinvasive disease cases by age group and gender, 1999-2005* * Reported as of 5/5/2006

25. Age Distribution of Fatal Human WNND Cases, United States, 2005*

26. Dengue Decision Support System (DDSS) Dengue Information System (DIS): GIS data repository Dengue surveillance Mosquito surveillance Insecticide resistance monitoring Dengue Resource Library (DRL): Data-base for Aedes aegypti insecticide resistance Dengue / Ae. aegypti pdf library Web-links to Ae. aegypti / dengue data-bases Dengue Models (DM): Mosquito simulation model (CIMSiM) Dengue simulation model (DENSiM) Dengue Decision Guide (DDG): Guidelines for usage of web- based DDSS Cost analyses Vector control guidelines Decision tree for dengue management IVCC-DDSS web-page