1. Cardiovascular system What makes up blood What makes up blood How blood is grouped and typed How blood is grouped and typed A simple look at how blood clots A simple look at how blood clots The heart chambers and how the blood flows through the heart The heart chambers and how the blood flows through the heart The pulmonary circulation and the systemic circulation The pulmonary circulation and the systemic circulation Blood pressure, pulse rates. Blood pressure, pulse rates. Some pathologies related to blood, heart and circulation. Some pathologies related to blood, heart and circulation.

3. Functions of Blood Function Brief description Transportation Waste/metabolites/nutrients/ gases (Oxygen, Carbon Dioxide) Hormones Protection Local – clotting  platelets Systemic – infection/ pathogens  wbc Regulatory tissue Fluid – electrolyte balance Acid base balance Body temperature

4. Physical Characteristics of blood Viscosity Density Color pH Temperature Volume

5. Components of blood Plasma = 55% Formed elements = 45%

6. Blood: 55% Plasma 91% Water 91% Water 9% Dissolved substances 9% Dissolved substances Salts (electrolytes) Salts (electrolytes) Respiratory gases Respiratory gases Hormones Hormones Waste & Metabolites Waste & Metabolites Plasma Proteins Plasma Proteins Albumins Albumins Globulins Globulins Fibrinogens Fibrinogens

7. Cardiovascular system 2 1. Blood typing 2. A simple look at how blood clots 3. Overview of the components of the cardiovascular System 1. Heart 2. Vessels 4. Gross Anatomy of the heart: 1. Surface Anatomy 2. Coverings and walls 3. Chambers 4. Great vessels of the heart

8. Blood: 45% Formed Elements Formed elements: Formed elements: White blood cells - clear ‘Buffy layer’ White blood cells - clear ‘Buffy layer’ 4-11,000wbc per mm volume of blood 4-11,000wbc per mm volume of blood Platelets 250,000 – 500,000 platelets per mm vol of blood 250,000 – 500,000 platelets per mm vol of blood – 99% Red blood cells – 99% 4-6 million rbc per mm vol of blood 4-6 million rbc per mm vol of blood 1000rbc : one wbc

9. Leucocytes Granulocytes Granulocytes Neutrophils Neutrophils Eosinophils Eosinophils Basophils Basophils Agranulocytes Agranulocytes Lymphocytes Lymphocytes Monocytes Monocytes

10. Platelets

11. A comparison of Red and White blood cells

12. Red blood cells 99% Red Blood Cells 99% Red Blood Cells White Blood Cells White Blood Cells Platelets Platelets

13. Hemoglobin

14. Blood typing

15. Cardiovascular system 3 1. Blood typing 2. A simple look at how blood clots 3. Overview of the components of the cardiovascular System 1. Heart 2. Vessels 4. Gross Anatomy of the heart: 1. Surface Anatomy 2. Coverings and walls 3. Chambers 4. Great vessels of the heart

16. Blood Typing - ABO Type O is universal donor

17. Blood Typing – Rh factor http://www.youtube.com/watch?v=7OWp8d8W Kkg&feature=related

18. Hemostasis (clotting) Stage summary Stage 1 Vasoconstriction Vascular spasms cause vessel to shrink – closing edges Chemicals released from damaged vessel wall activate next stage. Clotting factors released. Stage 2 Platelet Plug (mechanical ) Collagen exposed in damaged vessel wall stimulates platelet stickiness – plug formed by layers of platelets sticking together and to collagen. (Thrombus). Stage 3 Coagulation stage (chemical) Thrombin converts fibrinogen to fibrin – the mesh of the clot. Factor 13 stops the clotting cascade from continuing.