Presentation on theme: "Www.aids2014.org Usefulness and Validation of an Easy HIV Risk Practice and Clinical Conditions Questionnaire C. Gómez Ayerbe 1, A. Muriel 2, C. Santos."— Presentation transcript:
www.aids2014.org Usefulness and Validation of an Easy HIV Risk Practice and Clinical Conditions Questionnaire C. Gómez Ayerbe 1, A. Muriel 2, C. Santos 3, P. Pérez Elías 3, A. Díaz De Santiago 1, C. Quereda 1, R. Barea 3, L. Polo 3, E. Navas 1, J.M. Hermida 1, S. Moreno 1, M.J. Pérez Elías 1,4, DRIVE Study group. 1 Hospital Ramón y Cajal (HRyC), Infectious Diseases Department (Dep). 2 HRyC, CIBERESP, Statistics Dep. 3 Centro de Salud García Noblejas, Madrid, Spain. 4 IRYCIS, Madrid, Spain. THPDC0101
www.aids2014.org Background In Spain, the number of PLWHIV infection increases every year 1. Around 45-50% of the patients have a delayed diagnosis (<350 CD4/mcl) and 30% advanced disease (<200 CD4/mcl) 1. Moreover, up to 30% of the HIV patients are unaware of their own status 1. European Guidelines recommend HIV testing in persons with Risk Practices and/or Clinical Conditions (RP&CC) associated with HIV infection 2. RP&CC assessment should be done before indicating HIV testing, but in the clinical practice this is not routinely investigated. An structured RP&CC Questionnaire could increase a higher implementation of RP&CC assessment, and HIV testing. 1. CNE, ISCIII Annual Report 2013; 2. HIV in Europe, march 2012 www.hiveurope.eu; Conflict of Interest Disclosure No Conflict of interest
www.aids2014.org Materials and Methods Patients 18-60 years visiting Emergency Room or Primary Care Center were performed: 1) HIV- Risk Practice and Clinical Conditions Questionnaire 2) HIV-Rapid Test Results (1) Objetive To assess the Reliability, Feasibility and Predictability of an structured RP&CC Questionnaire.
www.aids2014.org Results (2) Conclusions 1.A reliable and Feasible self RP&CC Questionnaire discriminated all non HIV infected patients without missing any diagnosis. 2.Screening HIV RP&CC plus HIV testing in patients with RP&CC, offered a more efficient HIV screening strategy. 3.Best Predictability was obtained when combining Risk Practice and Clinical Conditions items. Sustancial RELIABILITY FEASIBILITY Self administered 90.8% Filled in paper98.1% Median time to complete 3 min (2-4) Needed clarification 17.9% Global Quest Risk Practice Clinical Conditions Sensitivity 100% (84.6-100) 86.4% (65.1- 97.1) 91% (70.8- 98.9) Specificity 49% (47.7-50.4) 61.3% (60- 62.6) 74.4% (73.2- 75.6) Positive Predictive Value 0.80% (0.50-1.22) 0.92% (0.55- 1.43) 1.45% (0.88- 2.23) Negative Predictive Value 100% (99.9-100) 99.9% (99.7- 100) 99.9% (99.8- 100) PREDICTABILITY