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Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation MAJ.

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Presentation on theme: "Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation MAJ."— Presentation transcript:

1 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation MAJ Jeremy L. Goodin Ph.D. OIC, Clinical Investigation Laboratory Clinical Investigation Research Laboratories: The Rest of the Story

2 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation Presentation Outline I.DCI Organization II.Roles of DCI Officer-in-Charge (OIC) III. Unique Capabilities IV. DCI Comparison to Army Research Institutes V. Conclusions

3 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation Disclaimer The content presented is the opinion of the author and does not reflect the views or policies of the U.S. Army. Mention of trade names, commercial products or organizations do not imply an endorsement by the U.S. government. Common Sense - identifying particular items of knowledge as "common sense" is difficult in the Army. Perception - What one perceives is a result of interplays between past experiences, including one’s culture, and the interpretation of the perceived. Relativism - the idea that some elements or aspects of experience or culture are relative to other elements or aspects. Humans can understand and evaluate beliefs and behaviors only in terms of their historical or cultural context.

4 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation DCI Mission Support graduate and continuing medical education Provide guidance and support for research Provide an academic milieu conducive to retention and recruitment of personnel Foster an atmosphere of inquiry Provide a review body for evaluation of research proposals Promote the highest level of professional standards in the conduct of human and animal research

5 Department of Clinical Investigation Research Laboratory and Education Section BLDG Fort Gordon GA Phone: Molecular Biology Section Staff Scientist Ph.D. Research Tech Physiology and Cellular Biology Section Staff Scientist Ph.D. Staff Scientist, Ph.D. Microbiology Section CPT-71A Biomedical Eng Laboratory Animal Support Veterinarian-DVM Animal Tech x 3 Chief, DCI Secretary Dept/Lab Manager Clinical Research Protocol Administrative Processing Section Case Manager Protocol Coordinator x 2 DCI Research and Training Laboratory OIC-71B NCOIC-E6 NCO-E5 Red = vacant Department of Clinical Investigation Research Administration Section DDEAMC, Fort Gordon GA Phone: Animal Use Section IACUC Function Human Use Section IRB Function Publication Review and Clearance Section Research, Education and Training for the Advancement of Military Medicine Regulatory Assurance and Regulated Studies Section 2Q FY 2010 Assistant Chief D.D. Eisenhower Army Medical Center Department of Clinical Investigation Human Protections Admin

6 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation Additional Personnel Contract Personnel 3-5 Research Assistants/Technicians 1 Biomedical Engineer 1 Statistician 1 Veterinarian 1-2 Assistant Protocol Coordinators Residents 3 full time surgery residents 3-6 additional medical residents 4-6 dental residents Volunteer Personnel

7 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation OIC Primary Duties Supervision and comprehensive management of the EAMC Clinical Investigation Research Facility. Responsible for successful execution of the DCI mission: multi- disciplinary military-relevant research, education and training programs. Rate or senior rate civilian and military personnel. Serve as senior military research scientist, principle investigator and subject matter expert for the medical and dental residency programs. Supervise the development of all clinical investigation research projects Serve as Chair, Institutional Animal Care and Use Committee (IACUC). Serve as acting DCI Chief as needed. Serve as Contracting Officer’s Representative for multiple contracts.

8 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation DCI Research Mission Unique Capabilities

9 Quantitative Real-time PCR Microarrays Immunohistochemistry Instron materials testing Confocal/Fluorescent Microscopy Kodak In-vivo FX Imager Faxitron X-ray Imager SEM Electron Microscope HPLC ELISA Nanodrop Spectrophotometry In-house Vivarium Surgical Suite Specialized Equipment

10 Laser Capture Microdissection System Allows for isolation of specific cells of interest from thin tissue sections Very useful for collection of specific cell types for DNA, RNA or protein analysis Modular Stage Breast Duct Epithelial Cells

11 Whitley MG500 Anaerobic Workstation

12 JSM Scanning Electron Microscope Bone Chip Disk 2000X

13 Application areas: Tensile strength testing Compressive strength testing Fatigue testing Flexural strength testing Impact force testing DCI testing has involved: Adhesive Sutures Resorbable Screws External Fixatures Instron 4502 Mechanical Strain Analysis System

14 Research Vivarium and Surgical Suite Animal models of human disease Training labs for procedures, surgeries

15 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation Comparison of MEDCEN Clinical Investigation to U.S. Army Research Institutes

16 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation METT-TC based comparison of U.S. Army Research Institutes to U.S. Army Clinical Investigation Laboratory

17 METT-TC: Mission Research InstituteClinical Investigation Research is the focusPatient care is the priority Funding driven, salaries directly tied to research proposals Less emphasis on funding, salaries part of hospital budget Applied science, Product oriented, Milestone driven Basic science, Product oriented, but the products are education and training © Jeff Jones 2010

18 METT-TC: Enemy Research InstituteClinical Investigation Bureaucracy Bureaucracy is the collective organizational structure, procedures, protocols, and set of regulations in place to manage activity.

19 METT-TC: Terrain and Weather Research InstituteClinical Investigation Similar to IndustrySimilar to Academia Very tight securityMuch less stringent security © Jeff Jones 2010

20 METT-TC: Troops and Support Research InstituteClinical Investigation ~ total workforce ~ military ~3,000 total workforce ~1,000 military All personnel and support focused on Research as the primary mission DCI personnel focused on Research, Education and Training Hospital support personnel turn around time can sometimes be slow

21 METT-TC: Time Research InstituteClinical Investigation Many “hard” deadlines and suspense dates due to funding cycles Some deadlines - residents have time constraints ~75% of time available to conduct research if in “investigator” position ~40% of time available to conduct research in OIC position ~0% of time available to conduct research if in management or staff officer position

22 METT-TC: Civil Considerations Research InstituteClinical Investigation Majority of workforce are civilian and contractor Civilian personnel issues may require a great deal of time and energy Civilian’s have added pressure of competitive funding

23 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation Mentorship LocationRaterSenior Rater Service School RIID-2003 (120 Day OER) 71A-LTC (Microbiology)71A-LTC RIID-2004DB3-Civilian (Scientist)71A-LTC RIID-2004DB4-Civilian (Scientist)71A-LTC Service School RIID-2006DB4-Civilian (Scientist)71A-LTC MRICD A-LTC (Microbiology)71B-COL (Dep CDR) MRICD D-LTC (Veterinarian)71B-COL (Dep CDR) MRICD-2009SES-Civilian (Operations)64C-COL (Dep CDR) MRICD-2009GS14-Civilian (Operations)64C-COL (Dep CDR) EAMC-2010YG3-Civilian (Physician)61F-COL (Dep CDR) (Physician)

24 Research, Education and Training for the Advancement of Military Medicine D.D. Eisenhower Army Medical Center Department of Clinical Investigation MAJ Jeremy L. Goodin Ph.D. OIC, Clinical Investigation Laboratory Questions?


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