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SALT KILLS The Mission. Coronary Artery Disease In Indians in USA ( CADI )

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Presentation on theme: "SALT KILLS The Mission. Coronary Artery Disease In Indians in USA ( CADI )"— Presentation transcript:

1 SALT KILLS The Mission

2 Coronary Artery Disease In Indians in USA ( CADI )

3 PUBLIC ENEMY # ONE High blood pressure Stroke Heart disease Obesity Osteoporosis Asthma Stomach cancer And of course, dementia 56 million Americans Affected

4 Salt and hypertension In 1952, Brookhaven's Lewis Dahl began his pioneering work connecting salt and hypertension. During 25 years of tests, he discovered that high salt intake was more dangerous in youth, and recommended that no salt should be added to baby foods. He also showed that a person's genetic background greatly affects their susceptibility to hypertension from salt.

5 Lewis K. Dahl

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7 INTERSALT

8 AGE BPBP 90/60 Yanomami Indians Range of BP and impact of age on BP

9 Jeremiah Stamler Father of Preventive Cardiology

10 “The INTERSALT study results, which agree with the findings from other diverse studies, including data from clinical observations, therapeutic interventions, randomized controlled trial, animal experimentation, physiologic investigations, evolutionary biology research, anthropology research, and epidemiologic studies, support the judgment that habitual high salt intake is one of the quantitatively important, preventable mass exposures causing the unfavorable population wide blood pressure pattern that is a major risk factor for epidemic cardiovascular disease.“…… …………….Stamler

11 “Ignoring the overwhelming scientific consensus on this issue…[is] supportive of positions adapted by special interests and comes at the expense of public health”.

12 Limit salt intake to 1500 mg a day

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14 Institute of Medicine STUDIES SUPPORT POPULATION BASED EFFORTS TO LOWER EXCESSIVE DIETARY SODIUM INTAKE EVIDENCE SUPPORTS A POSITIVE RELATIONSHIP BETWEEN HIGHER LEVELS OF SODIUM INTAKE AND RISK OF HEART DISEASE, IS CONSISTENT WIH PREVIOUS RESEARCH BASED ON SODIUM EFFECTS ON BLOOD PRESSURE MAY 14, 2013

15 1 MILLION people studied

16 Systolic Blood Pressure and Relative Cardiovascular Mortality Risk Cardiovascular mortality doubles for each 20 mmHg increase in blood pressure Systolic Blood Pressure Relative Risk of Cardiovascular Death Relative risk of cardiovascular mortality at prehypertension (systolic blood pressure of 140 mmHg)

17 One billion People with High blood pressure…..WHO Nine out Ten People do not Follow salt reduction…CDC Salt Content of Processed food unchanged…Multiple Sources

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19 Cardiac Hypertrophy From Fighting Hypertension

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22 Mitral Regurg From Hypertensive Cardiomyopathy

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24 Diastolic Dysfunction Lessons From ADHERE (Acute Decompensated Heart Failure Registry ) Over 5 Million Americans living with Heart Failure 250,000 Deaths per year 500,000 new cases per year 33% die within the first diagnosis Systolic function preserved in nearly half the patients Number One Reason for Hospitalization

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26 OSTEOPOROSIS FRACTURE Greater than combined risk of Breast and Ovarian Cancers Prostate cancer (1 in 3 women and 1in 5 men)

27 STROKE

28 Mechanisms of Dementia

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30 High blood pressure Increases the risk of memory loss by 600%

31 Auto-Immune Disease If you incrementally increase salt, you get generation after generation of these TH17 cells ….Vijay Kucheroo

32 The Real Public Enemy #1

33 SALT KILLS The Mission


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