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NON-LETHAL CHEMICAL AGENTS TOXICITY of CN and CS.

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Presentation on theme: "NON-LETHAL CHEMICAL AGENTS TOXICITY of CN and CS."— Presentation transcript:

1 NON-LETHAL CHEMICAL AGENTS TOXICITY of CN and CS

2 DEFINITION OF TERMS

3 m 3 = Cubic meter (Approximately 35 cubic feet) gm = Gram (0.353 oz.) mg =Milligram (0.001 grams - to convert grams to milligrams multiply by 1,000) cc = Cubic centimeter ( m 3 or 1.0 gm) 1 oz. = gm 66 minutes = time average man uses 1 m 3 of air

4 MEDIAN INCAPACITATION DOSAGE (IC 50 ) - The amount of inhaled vapor or aerosol which is sufficient to incapacitate 50% of exposed personnel. Usually expressed in milligrams per minute in one cubic meter of air.

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6 INCAPACITATION CONCENTRATION TIME (ICT 50 ) - Concentration (IC 50 ) multiplied by the time (t) of exposure that incapacitates 50% of exposed personnel. Usually expressed in minutes of exposure. !.004 mg/m 3 - smallest amount a human can detect. (British Government Study) ! 0.5 mg/m 3 - amount that riot bystanders usually retreat at. (British Government Study) ! 4.0 mg/m 3 - amount that rioters will usually disperse at. (British Government Study)

7 Waco, Texas

8 MEDIAN LETHAL DOSAGE (LC 50 ) - The amount of inhaled vapor or aerosol which is sufficient to kill 50% of exposed personnel. Usually expressed in milligrams per minute in one cubic meter of air.

9 LETHAL CONCENTRATION TIME (LCT 50 ) - Concentration (LC 50 ) multiplied by the time (t) of exposure that is lethal to 50% of exposed personnel. Usually expressed in minutes of exposure.

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12 SAFETY FACTOR - Ratio between the lethal and incapacitating dose of an agent (LCT 50 /ICT 50 ). CN:IC 50 = 20 milligrams per minute / cubic meter of air. LC 50 = 14,000 milligrams per minute / cubic meter of air SAFETY FACTOR OF 700 CS:IC 50 = 20 milligrams per minute / cubic meter of air. LC 50 = 25,000 milligrams per minute / cubic meter of air SAFETY FACTOR OF 1,250

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18 LCT 50 Calculators


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