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Notes: Skeletal Muscle Anatomy
(1) Levels of Organization Muscle (whole organ) Fascicle (portion of muscle) Muscle Fiber (single muscle cell) Myofibril (muscle cell organelle) Sarcomere (portion of myofibril) Myofilament (part of sarcomere) Macroscopic Microscopic
Muscle (organ) Fascicle Muscle Fiber (cell) Muscle Fiber (with many nuclei) Myofibril Sarcomere Thin Filament (actin) Thick Filament (myosin)
(2) Muscle Organ of muscular system Contains: –Muscle Cells –Connective Tissue –Blood Vessels & Nerves –Contractile Units Covered By: –Epimysium (outer tissue-membrane)
(3) Fascicle Portion of muscle-organ One step down from whole muscle Relationships: –Bunch of Fascicles = Muscle –Fascicle = Bunch of Muscle Fibers
(4) Muscle Fiber Actual Muscle Cell Contains: –Multiple nuclei –Striations –Complex organelles called myofibrils Relationships: –Bunch of Muscle Fibers = Fascicle –Muscle Fiber = Bunch of Myofibrils & Nuclei
(5) Myofibril Organelle in a muscle cell Contains: –Contractile Units (Sarcomere) Relationships: –Bunch of Myofibrils = Muscle Fiber –Myofibril = Bunch of Sarcomere
(6) Sarcomere Portion of myofibril Contains: –Contractile proteins –Thin filaments with actin –Thick filaments with myosin Relationships: –Bunch of Sarcomeres = Myofibril –Sarcomere = Bunch of Myofilaments (Actin + Myosin)
(7) Myofilaments Contractile portions of sarcomere Types: –Thin filaments w/actin (type of protein) –Thick filaments w/myosin (type of protein) Relationships: –Bunch of Myofilaments = Sarcomere –Myofilaments = DO THE CONTRACTIONS
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