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Buruli Ulcer Stephen Shenigo. What do you know?

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Presentation on theme: "Buruli Ulcer Stephen Shenigo. What do you know?"— Presentation transcript:

1 Buruli Ulcer Stephen Shenigo

2 What do you know? http://brendanomeara.com/?attachment_id=293

3 Buruli Ulcer was first Identified in 1897 by Sir Albert Cook http://images.wellcome.ac.uk/indexplus/result.html?_IXMAXHITS_=1&_IXACTION_=query&_I XFIRST_=7&_IXemailreal=true&_IXbox=28636&_IXSPFX_=templates%2Ft&_IXFPFX_=template s%2Ft http://www.infoplease.com/atlas/country/uganda.html

4 It was described in detail in 1948 by Peter MacCallum http://www.huu.unimelb.edu.au/university-history/150stories/maccallum.html http://www.lonelyplanet.com/maps/pacific/australia/

5 Mycobacterium ulcerans was identified in 1948 by Peter MacCallum http://jmm.sgmjournals.org/content/55/1/37.full http://www.huu.unimelb.edu.au/university-history/150stories/maccallum.html

6 Today the disease has been identified in 33 countries http://www.bvgh.org/Biopharmaceutical-Solutions/Global-Health-Primer/Diseases/cid/ViewDetails/ItemID/25.aspx

7 About half of the worldwide cases are in people under 15 <15 years Mean Med. Range Africa 48% 24 15 0.5–90 Australia 10% 50 62 1–96 Japan 19% 41 48 2–81 http://www.who.int/mediacentre/factsheets/fs199/en/

8 The disease starts as painless swelling on a particular area of the skin http://www.tropika.net/svc/news/20090415/Chinnock-20090415-News-Buruli-Conference

9 If left untreated this can turn into a full skin ulcer within 4 weeks http://en.wikipedia.org/wiki/File:Buruli_ulcer_hand_Nigeria.gif http://www.aifo.it/english/resources/online/courses/buruli/buruli12.htm

10 The disease itself does not necessarily kill people itself, but it does cause deformities http://factsanddetails.com/world.php?itemid=2153&catid=57&subcatid=381 http://www.leprosy.org/labi1

11 The way the disease is transmitted is still up for debate. http://en.wikipedia.org/wiki/Mosquito http://www.who.int/mediacentre/factsheets/fs199/en/ http://en.wikipedia.org/wiki/Common_ringtail_possum

12 How does the disease work? http://jmm.sgmjournals.org/content/55/1/37.full http://en.wikipedia.org/wiki/File:Mycolactone_2.png

13 Mycobacterium ulcerans emits mycolactone which destroys body tissues http://jmm.sgmjournals.org/content/55/1/37.full http://en.wikipedia.org/wiki/File:Mycolactone_2.png

14 Buruli Ulcer is diagnosed using IS2404 PCR http://www.casestudiesforglobalhealth.org/post.cfm/vaccine-development-collaborations- strengthen-pandemic-safety-scientific-possibilities http://en.wikipedia.org/wiki/Polymerase_chain_reaction

15 Treatment of Buruli Ulcer can be approached two different ways, using antibiotics or surgery http://en.wikipedia.org/wiki/File:Healed_Buruli_ulcer_lesions.jpg http://education.technyou.edu.au/view/242/antibiotics

16 There is not yet a specific vaccine for Buruli Ulcer http://www.tbonline.info/galleries/image/2/ http://theintelhub.com/2011/04/23/top-government-vaccine-researcher-indicted-for-fraud- austism-research-now-in-question/

17 HIV coinfection and paradoxical reaction can further complicate the disease. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652003000300012 http://biology.kenyon.edu/slonc/gene-web/Lentiviral/Lentivi2.html

18 The WHO along with several local organizations are coming together to start to try to fight this disease http://www.ghanacurrentjobs.com/job-vacancy-for-consultants-at-ghana-health-service http://www.truthalliance.net/Archive/ImageGallery/tabid/62/AlbumID/379-36/Default.aspx http://www.who.int/buruli/events/en/

19 Works Cited "Buruli Ulcer." World Health Organization. WHO, n.d. Web. 19 Nov 2012.. Hoover, Aaron Z.. "Buruli Ulcer." Medscape Reference. Medscape, 07 2012. Web. 19 Nov 2012. { "@context": "http://schema.org", "@type": "ImageObject", "contentUrl": "http://images.slideplayer.com/14/4372810/slides/slide_19.jpg", "name": "Works Cited Buruli Ulcer. World Health Organization.", "description": "WHO, n.d. Web. 19 Nov 2012.. Hoover, Aaron Z.. Buruli Ulcer. Medscape Reference. Medscape, 07 2012. Web. 19 Nov 2012.


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