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CASE STUDY OF FIVE PATIENTS SUFFERING DIABETIC FOOT ULCERS WHO WERE TREATED WITH A NOVEL DEBRIDING BROAD SPECTRUM ANTIMICROBIAL WOUND HEALER: ASSESSMENT.

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Presentation on theme: "CASE STUDY OF FIVE PATIENTS SUFFERING DIABETIC FOOT ULCERS WHO WERE TREATED WITH A NOVEL DEBRIDING BROAD SPECTRUM ANTIMICROBIAL WOUND HEALER: ASSESSMENT."— Presentation transcript:

1 CASE STUDY OF FIVE PATIENTS SUFFERING DIABETIC FOOT ULCERS WHO WERE TREATED WITH A NOVEL DEBRIDING BROAD SPECTRUM ANTIMICROBIAL WOUND HEALER: ASSESSMENT ON T.I.M.E. FRAMEWORK D Helin 1, A Spyckerelle 1, V De Corte², F Michels 1, J Van Der Bauwhede 1,G Vanhaverbeke 1 1 AZ Groeninge, Campus Onze-Lieve-Vrouw, Diabetic foot clinic, Reepkaai 4, 8500 Kortrijk, Belgium ² Flen Pharma NV, Blauwesteenstraat 87, Kontich, Belgium Introduction Diabetic foot ulcers remain a significant problem in health care with complications accompanying the disorder, which is a major cause of hospitalization. Although standards of care have been proposed, there is as yet no universal agreement about treatment. Care givers are confronted with a decision about which dressing to choose in order to optimally control exudates as well as keep the wound free from infection. The aim of this study was to assess the therapeutic outcome according to the T.I.M.E. concept in patients treated with a novel wound bio-healer (Flaminal ® ). Methods Five patients with diabetic foot ulcers were seen at a day clinic and the cause of the diabetic foot wound was determined. Wound treatment consisted of rinsing the ulcer with isotonic solution (0.9% NaCl) and disinfection with povidone-iodine solution. Flaminal ® was applied to the wounds and size, wound bed status, infection state and wound edges were assessed throughout treatment. In patient 1 and 5, relief of pressure on the foot sole was accomplished using a felt. Assessment within T.I.M.E. framework Results Of the five patients, four were suffering from neuropathy and one from angiopathy. Two patients showed complete recovery of the wounds, one within two months and one within three months. For the other three patients, a significant improvement according to the T.I.M.E. concept was established. There was a reduction in risk of infection. Wound exudate, wound edges and surrounding skin were controlled. All patients showed a favourable outcome of treatment within six months. Conclusion Our results showed that the new wound bio-healer (Flaminal ® ) was effective in the treatment of diabetic foot ulcers according to the T.I.M.E. concept. 20/4/ /7/2007 2/10/2007 T : necrosis on the small toe I : inflammation and high risk of infection M : no exudate E : soft T : amputation of the toe – fibrine and presence of a red wound bed I : high risk of infection M : few amounts of exudate E : no maceration T : granulation tissue clearly present I : no infection M : minimal amounts of exudate E : good closure Wound was healing optimally Patient information Table 1 indicates most important parameters of patients. Bold represents treated ulcer in this study. 11/12/2007 8/1/2008 T : red wound of certain depth I : inflammation M : few amounts of exudate E : maceration T : upgranulation of the wound I : no inflammation M : few amounts of exudate E : no maceration T : granulation tissue I : no infection M : minimal exudate E : epithelial advancement Clear progression towards complete healing 20/3/ /5/ /6/2007 T : necrosis – fibrine in wound bed –1,5 cm width I : inflammation – high risk of infection M : few to moderate amounts of exudate E : red wound edges T : granulation I : no infection M : minimal amounts of exudate E : healthy wound edges Wound almost completely healed 13/2/ /3/2007 T : red-yellow wound bed – wound of certain depth I : risk of infection M : few to moderate amounts of exudate E : callus T : satisfying granulation – red wound bed I : no infection M : few amounts of exudate E : healthy wound edges Diameter of the wound reduced by 50% T : healed I : no infection M : healed E : healed Complete healing of wound T : granulation – red wound bed I : no infection M : few amounts of exudate E : healthy wound edges Progression towards healing Wound progression in time 24/4/2007 8/4/ /7/ /10/2007 T : red wound bed – 2 cm diameter I : high risk of infection M : few amounts of exudate E : maceration T : good granulation – red wound bed – 1,5 cm diameter I : no infection M : few amounts of exudate E : healthy wound edges Satisfying progression of the wound healing process T : good granulation – 0,5 cm diameter I : no infection M : minimal amounts of exudate E : healthy wound edges Optimal healing of the wound 27/6/2007


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