Presentation on theme: "PROBABILISTIC DIETARY EXPOSURE ASSESSMENT TO PESTICIDE RESIDUES."— Presentation transcript:
PROBABILISTIC DIETARY EXPOSURE ASSESSMENT TO PESTICIDE RESIDUES
STRUCTURE Applications of probabilistic exposure assessments Pesticide conceptual model Exposure assessment to chlorpyrifos Input data Model settings Results of assessment Information on uncertainty Contribution of food items
APPLICATIONS Risk assessment for pesticide authorisation Risk assessment of registered pesticides Characterisation of variability and uncertainty Identification of the main contributions to the intake
EXPOSURE ASSESSMENT N Iterations Frequency Pear Residue Apple Residue Orange Residue Exposure = Σ(Consumption * Residue) / Bodyweight Consumption P A O 2 1 N 4 3
UNIT-TO-UNIT VARIABILITY Composite sample MEAN ANALYSIS ACUTE EXPOSURE ?
UNIT TO UNIT VARIABILITY OPTIONS No variability adjustment Concentration = mean for all units Variability GVDSP raw lab data Laboratory data for individual units Variability GVDSP lognormal Concentration in units described by a lognormal distribution Variability RIKILT No. Units in composite sample Concentration in units described by a Bernouilli distribution
LOGNORMAL VARIABILITY R Log(R,f(R, )) Distribution residues units x r1 +x r3x r2 + Intake = Distribution of residues Composite samples Consumption: 3 apples