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Cellular Reproduction. Why Cells Reproduce/Divide Growth Cell Repair Cell Replacement.

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Presentation on theme: "Cellular Reproduction. Why Cells Reproduce/Divide Growth Cell Repair Cell Replacement."— Presentation transcript:

1 Cellular Reproduction

2 Why Cells Reproduce/Divide Growth Cell Repair Cell Replacement

3 Why do cells multiply and not just grow bigger? 1.DNA overload: -the DNA can handle only so many requests for ‘information’ ex: library in growing town 2. Exchange of materials: -the cell must have enough surface area (cell membrane) to transport waste and nutrients into/out of cell -cells need HIGH surface area to volume ratio

4 Ratio of Surface Area to Volume in Cells 3:12:1

5 -if a cell gets too large, it is difficult to get sufficient amounts of oxygen and nutrients in and out of cell -this is why cells do not grow much even if the organism they are a part of does

6 -before it gets too large, a growing cell divides forming two daughter cells -called cell division -before the cell divides, it replicates(copies) all of its DNA -helps with information b/c each daughter cell gets its own genetic info

7 Chromosomes -carry genetic info -condensed form of DNA and protein -only visible during cell division b/c they come together -are copied before cell division to get two sister chromatids -chromatids are attached by centromeres -most human cells have 46 chromosomes (each with 2 sister chromatids)

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9 -a duplicated chromosome has two sister chromatids which become divided during mitosis and are distributed to each daughter cell

10 Cell Cycle -the series of events that cells go through as they grow and divide into two daughter cells -occurs in all cells (except sex cells) -every 20 hours in humans

11 Phases of the Cell Cycle INTERPHASE -longest phase of the cell cycle *G 1 : cell growth/making of organelles *S: chromosomes are copied to prep for mitosis (DNA replication) *G 2 : making of more organelles in prep for M phase, shortest phase of interphase

12 CELL DIVISION *M: division of the nucleus (mitosis) and the cytoplasm (cytokinesis) occurs -made up of five total steps

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14 Interphase -longest part of the cell cycle -3 distinct parts  G 1, S, G 2 -cell increases in mass -number of organelles doubles -DNA is duplicated

15 Interphase looks like: NucleusnucleolusNucleus and nucleolus visible. nuclear membrane nucleolus cell membrane chromatin

16 Maintaining Chromosome Number chromosomes (unduplicated) in parent cell at interphase same chromosomes (duplicated) in interphase prior to mitosis mitosis, cytoplasmic division chromosome (unduplicated) in daughter cell at interphase chromosome (unduplicated) in daughter cell at interphase

17 Mitosis – Division of the nucleus Made up of 4 smaller phases: 1.Prophase 2.Metaphase 3.Anaphase 4.Telophase *can last from a few minutes to a few days

18 Prophase longest of the 4 stages (50% of the time) nucleus and nucleolus disappear chromosomes become visible centrioles appear and separate spindle fibers gap the space in between the two centrioles

19 The Spindle Fibers -a web type structure made up of microtubule fibers -is essential for mitosis because it arranges the chromosomes into their correct positions to prep for cell division. Mitotic centre Microtubule A cell at metaphase a spindle

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22 Metaphase shortest phase (only a few minutes) chromosomes line up along the center of the cell centromeres attach to spindle fibers

23 Anaphase centromeres split chromatids move towards the separate poles (centrioles)

24 Telophase chromosomes become invisible again 2 distinct nuclei form

25 CYTOKINESIS: the separation of the cytoplasm between the two daughter cells begins during anaphase and usually extends past animal cells: -membrane pinches in on both sides until they meet in the center plant cells: -a cell plate forms (becomes new cell wall)

26 Animal Cell Division

27 Plant Cell Division cell wall former spindle equator cell plate vesicles converging

28 REVIEW:

29 Mitosis

30 Mitosis Part One

31 Mitosis Continued

32 Mitosis Song

33 Cell Turnover - The speed of mitosis -skin and epithelial cells have a rapid turnover in the human body in order to replace the ones constantly being worn away -cells which make up organs such as the eye and the brain, need not multiply as often once they reach adult size

34 -organs which need to produce new cells continuously have the highest turnover ex: bone marrow produces replacement blood cells

35 Cell Division Regulation: internal regulators: determine when phases occur ex: cyclin protein external regulators: respond to events outside cell ex: hormones uncontrolled growth is known as cancer

36 Meiosis -a process of reduction division in which the number of chromosomes per cell is cut in half through the separation of homologous chromosomes in a diploid cell homologous pairs- each chromosome set has one from male and one from female parent

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38 diploid- has both sets of homologous chromosomes haploid- has one set of chromosomes diploid (2N)  haploid (N) diploid = full set of chromosomes haploid = half set of chromosomes

39 -meiosis produces 4 haploid gamete cells from one diploid cell gametes cells- sex cells (egg and sperm)

40 -two rounds of cell division in meiosis -this is how the amount of chromosomes gets cut in half -homologous chromosomes are separated

41 Meiosis I -first round of division -homologous chromosomes separated Meiosis II -second round of division -chromosome number cut in half

42 MEIOSIS I and II

43 MEIOSIS I -similar to mitosis: *cell prepares for division *DNA is replicated BUT: *homologous chromosomes pair up *form a tetrad- made up of 4 chromatids **called synapsis *exchange portions of their genes *called crossing over (this adds to diversity)

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46 MEIOSIS II -no interphase II (no more DNA replication) -very similar to mitosis -chromosomes line up as individuals, have already been separated from partner -sister chromatids split

47 PROPHASE II

48 METAPHASE II

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50 TELOPHASE II and CYTOKINESIS

51 During meiosis: -chromosomes independently assort (separation of genes during gamete formation) -haploid gametes in men = sperm cell -haploid gametes in women = egg cell *other three cells (in females) are called polar bodies

52 MITOSISMEIOSIS -2 identical diploid cells-4 different haploid cells -only in asexual reproduction -occurs during sexual reproduction -allows for replacement and growth of cells -produces gamete cells

53 Meiosis


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