Presentation is loading. Please wait.

Presentation is loading. Please wait.

27th January, 2010. Recent Product Launches S5/S5i VH™ IVUS Revolution catheter Latest Acquisitions IP and Core Technologies Jomed 2003 Philips (Rotational.

Similar presentations


Presentation on theme: "27th January, 2010. Recent Product Launches S5/S5i VH™ IVUS Revolution catheter Latest Acquisitions IP and Core Technologies Jomed 2003 Philips (Rotational."— Presentation transcript:

1 27th January, 2010

2 Recent Product Launches S5/S5i VH™ IVUS Revolution catheter Latest Acquisitions IP and Core Technologies Jomed 2003 Philips (Rotational IVUS IP) 2004 Cleveland Clinic VH 2002 Initial venture funding in February 2001 Volcano Story Current family of products all introduced in last 2 years Current family of products all introduced in last 2 years FFR PrimeWire Novelis Forward Looking IVUS 2008 CardioSpectra OCT catheter 2007 Axsun Laser OCT 2008

3 Manufacturing Headquarters Rancho Cordova, CA Corporate Headquarters San Diego, CA Advanced Technology Lab Cleveland, OH Volcano Europe Brussels, Belgium Volcano Japan Tokyo, Japan Volcano China, Hong Kong, China Volcano Global Sales Atlanta, GA Volcano OCT Division San Antonio, TX Volcano MA Andover, MA

4 Volcano Today Platform technologies for improving endovascular procedures 200+ global patents in IVUS, VH, FM, FL.IVUS and OCT Technology actor in interventional cardiology diagnostic Recent clinical studies: FAME and PROSPECT reinforce the use of FFR and IVUS (VH) to improve PCI’s outcome Numerous additional large market opportunities Over 100 R&D engineers and scientists dedicated to new and existing technology Research Facilities in San Diego, Sacramento, Andover, San Antonio, Cleveland Established global business with a track record of success Over 3,700 installed systems worldwide (>50% of hospitals with cath labs)

5 Volcano Platform 1.Volcano s5: 5 modalities on 1system 2. IVUS and FFR Integration with all X-ray Compagnies Compatibility with GE, Philips, Siemens, Toshiba 3. Coronary and Peripheral Applications 4. Vision for the future –IVUS Guide Therapy, OCT, FL IVUS available soon on one multi-modality platform

6 IVUS and FFR PIM can hang from bed rail s5i control devices can be located at bedside and/or in control room s5i image on main bank and in control room Flexible, custom integration, through collaboration with cath lab vendors (GE, Philips, Siemens) Volcano s5 i Integrated Cath Labs

7 GE Philips Siemens Toshiba IVUS/FFR integrated in every Cath lab type

8 Choice of 5 unique modalities

9 Revolution™ high frequency rotational IVUS for longer pullbacks and clinical study design Choice of 5 unique modalities

10 Digital gray scale IVUS for fast, plug and play imaging Choice of 5 unique modalities

11 ChromaFlo® stent apposition assessment to quickly confirm desired stent expansion and placement Choice of 5 unique modalities

12 VH® IVUS tissue characterisation to identification of necrotic core

13 PrimeWire™ FFR functionality for reliable identification of ischemic lesions as seen in FAME Choice of 5 unique modalities

14 Leadership through Vision The development, release and timing of any features or functionality described for our products remains at the sole discretion of the company. 14 SOLID STATE IVUS ROTATIONAL IVUS FFR 2010 Product Introductions Pioneer/ Medtronic IGT OCT 2H 2010 IGT Balloon 1H 2010 FL.IVUS 1H 2010 FL.IVUS Therapy 1H Product Introductions

15 IVUS Guided Therapy - VIBE Combined IVUS and Balloon IVUS Platform : Eagle Eye Platinum Balloon semi- and non-compliant

16 Assess the vessel morphology and pre-DILATE if necessary for stent preparation Imaging the vessel lumen & wall structures (IVUS-VH) as an adjunct to conventional angiographic procedures for adequate geographic stent placement Balloon dilatation of a stenotic portion of a coronary artery or bypass graft stenosis for the purpose of improving myocardial perfusion Balloon dilatation of a stent after implantation IVUS Guided Therapy - VIBE

17 OCT provides a super high resolution tool to guide; –proper lumen sizing –full stent apposition –optimal stent expansion Volcano OCT Optical Coherence Tomography

18 OCT can provide a super high resolution tool to identify; –Intraluminal thrombus –Thin cap fibroatheromas (10-15 micron resolution) –Other? Stent with acute formation of white thrombus Volcano OCT Optical Coherence Tomography

19 Proposed Volcano OCT Components – Super-fast Spectral Domain imaging catheter Does not require balloon occlusion for blood clearance Similar to rotational IVUS design micron axial resolution – Bedside user controls The same user interface controls IVUS and FFR – Image on existing monitor bank The development, release and timing of any features or functionality described for our products remains at the sole discretion of the company. Volcano OCT Optical Coherence Tomography

20 Forward Looking IVUS

21 PreView™ –Catheter-based –1.5 mm imaging offset from tip –45 degree off-set forward looking cone –5 mm forward –Imagine a funnel centred at your eye and looking forward Mackinaw™ –Same image –Pulsed RF energy delivered to ‘red’ target –Steering is enabled by rotating the catheter and moving the target 5 mm ahead of catheter tip Ablation Region Vessel Lumen New Ultrasound Lines Intima Media Adventitia 2 mm ahead of catheter tip

22 CTOs indication Successful product requires 3 attributes –Visualization, Steering, Dissection Design Considerations –Compatible with CTO guidewire of choice –Ability to visualize at 45 degrees when catheter approaches vessel wall Passive version for visualization only –Preview™ Active version equipped with RF ablation –Mackinaw™ These Volcano Products are not currently available for sale. This document implies no guarantee as to future delivery or timing of these programs, and is meant only to highlight Volcano’s recent research & development efforts Volcano FL.IVUS Forward Looking IVUS to facilitate CTO crossing

23 FAME study: FFR vs. Angiography for Multivessel Evaluation Demonstrated in 1,005 patients receiving DES for multi-vessel disease that FFR-guided PCIs resulted in lower MACE rates than angio-guided PCIs  A gap in MACE rates was evident within 30 days  FFR guidance used during the PCI procedure  shifted the survival curve upward  resulted in superior clinical outcomes Vs Angio  FFR guidance improves clinical outcomes in patients receiving DES for multi-vessel disease  FFR cost effective Vs Angio guided PCI 2 Years FU

24 The PROSPECT Trial : A Natural History Study of Atherosclerosis Using Multimodality Intracoronary Imaging to Prospectively Identify Vulnerable Plaque 3-vessel imaging post PCI Culprit artery, followed by non-culprit arteries Angiography (QCA of entire coronary tree) IVUS Virtual histology Palpography (n=~350) Repeat imaging in pts with events Meds rec Aspirin Plavix 1yr Statin Repeat 30 days, 6 months Proximal 6-8 cm of each coronary artery MSCTSubstudyN= F/U: 1 mo, 6 mo, 1 yr, 2 yr, ±3-5 yrs F/U: 1 mo, 6 mo, 1 yr, 2 yr, ±3-5 yrs

25 The PROSPECT Trial : A Natural History Study of Atherosclerosis Using Multimodality Intracoronary Imaging to Prospectively Identify Vulnerable Plaque 20% of pts with ACS successfully treated with stents and contemporary medical Rx develop MACE within 3 years, with adverse events equally attributable to recurrence at originally treated culprit lesions (treatment failure) and to previously untreated non culprit coronary segment 12% of pts develop MACE from non culprit lesions during 3 years of follow-up The combination of large plaque burden (IVUS) and a large necrotic core without a visible cap (VH- TCFA) identifies lesions which are at especially high risk for future adverse cardiovascular events

26 The PROSPECT Trial : A Natural History Study of Atherosclerosis Using Multimodality Intracoronary Imaging to Prospectively Identify Vulnerable Plaque VH-TCFA (Thick Cap Fibrous Atheroma) and Non Culprit Lesion Related Events Positive predictive value for future events PIT (Pathological Intimal Thickening) and Non Culprit Lesion Related Events Negative predictive value for future events

27 Summary 1.Volcano multimodalities in one platform –Five options in one system… available today! 2.DICOM / Worklist Compatible –Both DICOM store and Worklist 3.Endorsement by cath lab manufactures –Letters of compatibility with GE, Philips, Siemens 4.Coronary Applications –Full line of catheters for diagnosis and therapy guidance 5.Vision for the future –Track record of success, clear plan for the future 6.Make Volcano ‘essential’ to every cath lab –Our Vision is to make IVUS, FFR, VIBE, OCT, FL.IVUS, etc. all available through the same user interface and workflow

28 Volcano provides the two pivotal technologies that clearly improve PCI: IVUS/VH and FFR Volcano provides diagnostic solutions to optimise the treatment of stable, unstable and AMI patients Volcano future OCT, FL IVUS, VIBE options will continue to improve PCI’s outcome. Angio alone is not enough

29 Right Patient, right lesion, right way!


Download ppt "27th January, 2010. Recent Product Launches S5/S5i VH™ IVUS Revolution catheter Latest Acquisitions IP and Core Technologies Jomed 2003 Philips (Rotational."

Similar presentations


Ads by Google