POPPHI 2009 UPDATE NON-PNEUMATIC ANTI- SHOCK GARMENT (NASG) POPPHI 2009 UPDATE SUELLEN MILLER, CNM, PHD DIRECTOR, SAFE MOTHERHOOD PROGRAMS, BIXBY CENTER FOR GLOBAL REPRODUCTIVE HEALTH, UCSF Presented by Carinne Meyer, MA, MPH
The NASG: Low-cost, Low Tech Life Saving Device
Update on Research Nigeria: Pre-Post Study (Completed) Egypt: Pre-Post Study (Completed) Zambia/Zimbabwe: Cluster Randomized Trial (In Progress)
Nigeria Study (Mar. 04 – Nov. 08) Pre-intervention/intervention study design 12 referral hospitals in Northern and Southern Nigeria Entry criteria were OH of any etiology (> = 750 ml) and one clinical sign of shock. Outcomes: mean measured blood loss and mortality. PhaseN=756 Pre-intervention /Standard Treatment 182 Intervention / NASG574
Egypt Study (June 06 – May 08) Pre-intervention/intervention study design 2 referral facilities in Egypt Entry criteria were OH of any etiology (> = 750 ml) and one clinical sign of shock. Outcomes: mean measured blood loss, mortality, severe morbidities and extreme adverse outcomes. PhaseN=990 Pre-intervention /Standard Treatment 432 Intervention / NASG558
Zambia/Zimbabwe RCT Design: Cluster Randomized Trial Funding: NIH and Gates Foundation Data Coordination: WHO, RHRU Data Management: Centro Rosario Estudios Perinatales (CREP) (Argentina) OpenClinica Research Collaboration: University Teaching Hospital in Lusaka, Zambia and the University of Zimbabwe (UZ-UCSF RH Collaborative)
Why a RCT? The RCT is designed to early application determine if early application at the primary care level by midwives will IMPROVE MATERNAL OUTCOMES.