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Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. MICHAEL D. JOHNSON CANCER: UNCONTROLLED CELL DIVISION AND DIFFERENTIATION CHAPTER 18 CANCER: UNCONTROLLED CELL DIVISION AND DIFFERENTIATION PowerPoint ® Lecture Slide Presentation by Robert J. Sullivan, Marist College Human Biology Concepts and Current Issues Second Edition
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Characteristics of Benign Tumors and Cancers Table 18.1
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Benign Remain in one location Single, well defined mass May be surrounded by connective tissue Cancerous Abnormal cell structure, may appear undifferentiated May spread Edge of tumor not clearly defined Tumors
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Malignant Tumor Development Figure 18.2
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Dysplasia: abnormal change in cell structure In Situ Cancer: malignant tumor in only one place Matastases: secondary tumors at other locations Cancerous Cells: Lose Control Over Cell Functions
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Mutated or damaged genes Proto-oncogenes: normal regulatory genes Oncogenes: mutated or damaged proto-oncogenes Tumor suppressor genes: regulatory genes repress cell growth, division, differentiation, adhesion May be turned off, damaged or mutated in cancers How Cancer Develops
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Carcinogens Table 18.2
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Tumor imaging: X-rays, PET, MRI Genetic testing: identify mutated genes, privacy and treatment issues Enzyme tests for cancer markers: screening large numbers of people Advances in Diagnosis: Early Detection
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Conventional treatments: surgery, radiation, and chemotherapy Immunotherapy: promotes the immune response Starving cancers: inhibits angiogenesis Molecular treatments: target oncogenes Cancer Treatments
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Ten Most Common Cancers Table 18.3
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Skin cancer: three major types Breast cancer: almost exclusively in women Prostate cancer: most common after age 50 in males Lung cancer: smoking is the leading risk factor Cancers of colon and rectum: early detection has increased survival rates to 62% Most Common Cancers
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Lymphoma: related to altered immune function Urinary bladder cancer: surgery needed early Cancer of the uterus: includes cervical cancer and cancer of the endometrium Leukemia: chemotherapy often effective Cancers of mouth and pharynx: tobacco major risk Most Common Cancers ( cont.)
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Know family history Get regular medical screenings Learn self-examination techniques Avoid direct sunlight 10 AM to 4 PM, avoid sunlamps and tanning salons Watch diet and weight Don’t smoke Drink in moderation, if at all Be informed Most Cancers are Preventable
CANCER: CANCER: CHAPTER 18 DNA TECHNOLOGY & GENETIC ENGINEERING: DNA TECHNOLOGY & GENETIC ENGINEERING: CHAPTER 20 +
Copyright © 2009 Pearson Education, Inc. Selected sections from Chapter 18 Cancer: Uncontrolled Cell Division and Differentiation Tumor Benign Malignant.
Copyright © 2006 Pearson Education, Inc. publishing as Benjamin Cummings.
Bio 130 Human Biology Cancer Normal cells have regulation that keeps their rates of cell division in check. Normal cells generally remain in one location.
Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings PowerPoint ® Lecture Slide Presentation prepared by Michael Hall Cancer:
Mayfield Publishing Company Cancer Basics The abnormal, uncontrolled growth of cells, which if left untreated, can ultimately cause death 85 million.
Cancer What is cancer? uncontrolled cell growth that leads to the formation of primary tumors cells that spread (metastasize) to other areas of the body.
1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Human Biology Sylvia S. Mader Michael Windelspecht Chapter.
Copyright © 2005 Pearson Education, Inc., publishing as Benjamin Cummings PowerPoint ® Lecture prepared by Jan Campbell T H E B A S I C S SIXTH EDITION.
CELL DIVISION GOING WRONG: Cancer When cells grow and divide out of control, they cause a group of diseases called cancer.cancer The result is a change.
BIOLOGY CONCEPTS & CONNECTIONS Fourth Edition Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Neil A. Campbell Jane B. Reece Lawrence.
Cancer: Another way to think of cancer is “Mitosis Run Amok.”
Rapid and uncontrollable development and production of cells.
Your “Do Now”3/19 Take a paper from up front Complete the “Before” section, questions 1-5 Be prepared to share-out.
Aim: What happens if the rate of mitosis is abnormal? HW: Castle Learning.
© 2015 Pearson Education, Inc. PowerPoint Lectures Campbell Biology: Concepts & Connections, Eighth Edition REECE TAYLOR SIMON DICKEY HOGAN Chapter 11.
LESSON 14.3 “Cancer”. Cancer: a group of diseases in which cells divide in an uncontrolled manner. Not contagious Not caused by injury Causes are not.
Cancer AN INTRODUCTION Cancer - An Introduction 1.
Cancer. What is cancer? Simply put, cancer is cell division that happens uncontrollably. If a cell does not receive a signal to stop dividing, unchecked.
Non-Communicable Diseases Disease that is not transmitted by another person, a vector, or the environment Cardiovascular Disease is one of the most common.
SC430 Molecular Cell Biology Welcome to Our Last Seminar - Unit 9 Tonight we will discuss –Cancer, cancer treatment and prevention –I will be available.
Cell Processes & Energy Cancer Chapter 2 Section 4.
Cancer. What does the word cancer mean to you? What is Cancer? Cancer - disease where cells grow out of control and invade, erode and destroy normal.
Understanding Cancer Developed by: Lewis J. Kleinsmith, Ph.D. Donna Kerrigan, M.S. Jeanne Kelly Brian Hollen.
Understanding Cancer and Related Topics Understanding Cancer.
Understanding Cancer. What Is Cancer? Different Kinds of Cancer Lung Breast (women) Colon Bladder Prostate (men) Some common sarcomas: Fat Bone Muscle.
Aim: How can mitosis lead to a disruption in homeostasis? Understanding Cancer.
By: Amanda Herrod CANCER. What Is Cancer? Cancer is a disease which abnormal cells divide without control and are able to invade other tissues. Cancer.
Cell Division Gone Wrong Cancer. Cancer is a disease of uncontrolled cell division. It starts with a single cell that loses its control mechanisms due.
CANCER A. Characteristics of Cancer Cells 1. Structural Abnormalities a. Has an abnormal large nucleus and less cytoplasm then usual b. Poorly differentiated.
Cancer. Lung Breast (women) Colon Bladder Prostate (men) Fat Bone Muscle Lymph nodes Bloodstream What are some different kinds of cancer?
Ultraviolet (UV) rays can put a person at risk for developing cancer. How does each item in the picture help protect you from UV rays? Cancer.
Cancer =Uncontrolled cell growth due to gene mutations -Cancer is always genetic, but it is not necessarily inherited.
Aim: What happens if the rate of mitosis is abnormal? Do Now: Describe the process of mitosis? What has to happen to the chromosomes before a cell dovides?
CELL CYCLE REGULATION & CANCER. NORMAL CELL CYCLE Cyclins : proteins CDKs (Cyclin dependent kinases): enzymes Cyclins and CDKs bind together to activate.
Answer the following questions independently. If you don’t know the answer, make the best possible educated guess you can. Do not leave any questions.
Cancer What is cancer? How does it form? How can it be treated?
10.3-Regulating the Cell Cycle Controls on Cell Division The cell cycle is controlled by regulatory proteins both inside and outside the cell. Cyclins.
Chapter 13: Reducing Your Risk of Cancer Cancer is a group of diseases characterized by uncontrolled, disorderly cell growth Cancer is the second-leading.
Chapter Definition: An abnormal and uncontrolled growth of cells that can lead to death Tumor: A mass of tissue that serves no physiological.
Cancer: The Intimate Enemy Honors Anatomy & Physiology
Bellringer What does the word cancer make you think of?
…cells that cannot control their growth rate and continue to divide without dying o This forms tumors o Cells usually invade nearby tissue and often spread.
VIII. CANCER = Uncontrolled Cell Division. Celebs with Cancer.
Aim: How can mitosis lead to a disruption in homeostasis?
By the end of this lecture, students will learn: 1.What is cancer. 2.Genetics of cancer. 3.Oncogenes 4.Tumor suppressor genes. 5.DNA Repair genes 6.Genes.
Cancer Over a hundred diseases are called cancer..
Disorders of Cell Growth Cancer. Oncology Study of cancer 25% of Americans develop cancer at some point in life.
Chapter 19 Cancer. Points to Ponder What are characteristics of cancer cells? What are the 3 stages in the development of cancer? What is angiogenesis.
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