We think you have liked this presentation. If you wish to download it, please recommend it to your friends in any social system. Share buttons are a little bit lower. Thank you!
Presentation is loading. Please wait.
Published byEthel Terry
Modified about 1 year ago
HES1 Is a Master Regulator of Glucocorticoid Receptor– Dependent Gene Expression by Javier R. Revollo, Robert H. Oakley, Nick Z. Lu, Mahita Kadmiel, Maheer Gandhavadi, and John A. Cidlowski Sci. Signal. Volume 6(304):ra103-ra103 December 3, 2013 ©2013 by American Association for the Advancement of Science
GR signaling represses the expression of HES1. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
Glucocorticoids require RelA (p65) to repress HES1. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
HES1 alters GR signaling. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
HES1 requires DNA binding to inhibit GR signaling. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
Glucocorticoids repress HES1 expression in hepatocytes. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
Ablation of liver HES1 alters GR signaling. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
HES1 regulates glucocorticoid-mediated IGFBP1 gene induction. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
Glucose tolerance tests. Javier R. Revollo et al., Sci. Signal. 2013;6:ra103 ©2013 by American Association for the Advancement of Science
Identification of a Lysosomal Pathway That Modulates Glucocorticoid Signaling and the Inflammatory Response by Yuanzheng He, Yong Xu, Chenghai Zhang, Xiang.
by Kevin J. Paavola, Harwin Sidik, J
TREM2- and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1 by Qisheng Peng, Shikha Malhotra, James A. Torchia, William G. Kerr,
T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia by Michael Kalos, Bruce.
Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration by Jeanine Pignatelli, Sumanta Goswami,
Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes.
First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip by Robert Farra, Norman F. Sheppard, Laura McCabe, Robert M. Neer, James M. Anderson,
Gene Expression Chapter 16. DNA regulatory sequence All on DNA Promoters – Start transcription Promoters – Start transcription Terminators – End Transcription.
Nuclear Envelope Lamin-A Couples Actin Dynamics with Immunological Synapse Architecture and T Cell Activation by José M. González-Granado, Carlos Silvestre-Roig,
We used chicken embryos as models for this experiment. Chicken embryos were injected on day 13 with the following treatments for a 2 day treatment period:
Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase by Mayra García, Arik Cooper, Wei Shi, William Bornmann, Ricardo Carrion,
Genetics: Chapter 7. What is genetics? The science of heredity; includes the study of genes, how they carry information, how they are replicated, how.
SEUNG-HOI KOO Sungkyunkwan University, School of Medicine Regulation of Hepatic Glucose Metabolism.
Gene Expression and Regulation
Cancer Genome Landscapes by Bert Vogelstein, Nickolas Papadopoulos, Victor E. Velculescu, Shibin Zhou, Luis A. Diaz, and Kenneth W. Kinzler Science Volume.
Chapter 3 SIMILARITIES AND DIFFERENCES BETWEEN CELLS.
Gene Regulation 8/24/2015. DNA Binding Proteins Histones Sequence specific DNA major grove Homodimeric Inverted repeats 8/24/2015.
20,000 GENES IN HUMAN GENOME; WHAT WOULD HAPPEN IF ALL THESE GENES WERE EXPRESSED IN EVERY CELL IN YOUR BODY? WHAT WOULD HAPPEN IF THEY WERE EXPRESSED.
N. Mitro et al. Nature advance online publication 24 December 2006 doi: /nature05449
Regulation of gene and cellular activity
Modulation of NF ‐ κB ‐ dependent transcription and cell survival by the SIRT1 deacetylase by Fan Yeung, Jamie E Hoberg, Catherine S Ramsey, Michael D.
1 Familial Hypercholesterolemia (FH): Premature Cardiovascular Risk Reduction Through Early Action.
A Robust and Sensitive Synthetic Sensor to Monitor the Transcriptional Output of the Cytokinin Signaling Network in Planta by Evelyne Zürcher, Deborah.
Lecture12 - Based on Chapter 18 - Regulation of Gene Expression in Eukaryotes I Copyright © 2010 Pearson Education Inc.
Microbial Genetics - DNA Transfer l Review of Information Transfer in Cell l Recombination l Transfer of DNA &Genetic Recombination in Bacteria –Conjugation.
Gene Sleuthing Lorraine Sartori Majid Masso Paul R. McCreary.
Impaired T-cell responses to sphingosine-1-phosphate in HIV-1 infected lymph nodes by Joseph C. Mudd, Patrick Murphy, Maura Manion, Robert Debernardo,
Tyrosine kinase signalling (review) TGF signalling Notch signalling.
Progress in Cancer Therapy Following Developments in Biopharma Faculty of Biology June 2015 Danielle Neufeld & Anna Rabinovich.
Interactions Between Vitamin D and Androgen Receptor Signaling in Prostate Cancer Cells Nancy L. Weigel, Ph.D. Baylor College of Medicine.
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer by Yun ‐ Yong Park, Kyounghyun Kim,
Epigenetic Regulation of the Glucocorticoid receptor in human brain associates with childhood abuse Patrick O McGowan, Aya Sasaki, ana c D’Alessio, Sergiy.
Cytokines, Growth Factors and Hormones SIGMA-ALDRICH.
Role of heat shock proteins in aging A&S Jim Lund.
Regulation of IGF and IGF binding protein gene expression by nutrition and aquaculture related stressors: Implications in fish growth and stress assessment.
EUKARYOTIC CELL SIGNALING VII Abnormal Signaling in Cancer Signaling to p53 Dr. Ke Shuai Office: 9-240M Factor Tel: X69168
Regulation of Gene Expression. Prokaryotes –Constituitive Gene Expression (promoters) –Regulating Metabolism (promoters and operators) –Regulating Development.
OUTLINE 3 III.Control of Gene Expression in Prokaryotes A. Regulatory proteins B. The operon model C. Examples 1. the lac operon (substrate induction)
Gene Regulation, Part 1 Lecture 15 Fall Metabolic Control in Bacteria Regulate enzymes already present –Feedback Inhibition –Fast response Control.
Title Chapter 13 Gene regulation. CO 13 Fig
IGF in circulation The majority (> 75 %) exists as bound form –IGF binding proteins (IGFBPs) IGFBPs –6 proteins and several related proteins –Serum IGFBP.
Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B- cell lymphomas by Lingchen Fu, Yen-Chiu Lin-Lee,
HAWAIIAN SKIRT: An F-Box Gene That Regulates Organ Fusion and Growth in Arabidopsis by Zinnia H. González-Carranza, Unchalee Rompa, Janny L. Peters, Anuj.
FINAL IN FOWLER A103B TUESDAY, JUNE 14 11:30 AM -- 2:30 PM POINTS FROM MIDTERM QUESTIONS POINTS FROM FINAL QUESTIONS.
Caption N-terminal domain A/B domain: ligand-independent domain AF1: Activation Function 1 DBD: DNA Binding Domain LBD: Ligand Binding Domain: ligand-dependent.
Announcements 1. Reading Ch. 15: skim btm Look over problems Ch. 15: 5, 6, 7.
Life is Dynamic. The information Regulated by proteins.
Study of glucocorticoid receptors in human synovial fibroblast cells: response to dexamethasone and cytokines. Professor Nelson Fernández Department of.
© 2017 SlidePlayer.com Inc. All rights reserved.