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Introduction to Muscle Anatomy. Types of Muscle 1. Skeletal –Elongated Cells –Multi nucleated –Striated – striped appearance –Voluntary –Produces powerful.

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Presentation on theme: "Introduction to Muscle Anatomy. Types of Muscle 1. Skeletal –Elongated Cells –Multi nucleated –Striated – striped appearance –Voluntary –Produces powerful."— Presentation transcript:

1 Introduction to Muscle Anatomy

2 Types of Muscle 1. Skeletal –Elongated Cells –Multi nucleated –Striated – striped appearance –Voluntary –Produces powerful contractions –Tires easily, needs rest (fatigue). –Covers bony skeleton (motility) Cross Section Notice nuclei around outside of cell. Longitudinal View Notice striations and nuclei around outside of cell.

3 Skeletal Muscle Composite Sketch

4 2. Smooth –Spindle-shaped Cell –Single nucleus in each cell –No Striations –Involuntary –Slow, sustained contractions –In hollow visceral organs (stomach, bladder, respiratory passages) Cross Section Nucleus is in center of cell. Cells much smaller.

5 Smooth Muscle Composite Sketch

6 3. Cardiac (Heart) –Branched cell –Contain intercalated discs –Single nucleus in each cell –Striations –Involuntary –Steady, constant contractions –Never tires

7 Cardiac Muscle Composite Sketch

8 Muscle Functions Produce movement –locomotion & manipulation –Help blood move through veins & food thru small intestines Maintain posture Stabilize joints Body temp homeostasis –Shivering: movement produces heat energy

9 Muscle Requirements Demands continuous oxygen/nutrient supply. –Lots of arteries/capillaries to muscle. Each muscle cell w/ its own nerve ending controlling its activity. Produce much metabolic waste due to constant activity. Motor end plate (terminus) Axon of neuron

10 Muscle Attachments Most muscles span joints Attaches to bone in two places: (video)video 1. Insertion: the moveable bone Bicep insertion is the radius 2. Origin: the stationary bone bicep originates in two different places in scapula Attachment types 1.Direct: attaches right onto bone - ex. intercostal muscles of ribs 2.Indirect: via tendon or aponeurosis (sheet-like tendon) to connect to bone - leaves bone markings such as tubercle

11 Muscle Organization Muscles are complex bundled structures: fibers within fibers

12 Muscle organization Muscle (organ) Fascicle Muscle fiber (cell) Myofibril Sarcomere Myofilaments: Actin & Myosin

13 Muscle Fibers A Muscle Fiber = Muscle Cell HUGE cell: –  m in diameter –can be hundreds of centimeters long (created by cytoplasmic fusion of multiple embryonic cells) –extends the length of the muscle Main content: bundles of proteins (actin and myosin) Multinucleated –to maintain high rate of protein synthesis. –Muscle fiber nucleus = myonucleus

14 Insulation of Muscles Muscle cells must be insulated from one another by specialized membranes Muscle cells work electrically –if not insulated, nerves cannot control individual muscles.

15 Epimysium surrounds entire muscle –Dense CT that merges with tendon –Epi = outer –Mys = muscle Perimysium surrounds muscle fascicles –Peri = around –Within a muscle fascicle are many muscle fibers Endomysium surrounds muscle fiber –Endo = within

16 Structural Terminology Associated with Muscle Fibers Prefixes: myo, mys, and sarco all refer to muscle Sacroplasmic Reticulum = Smooth ER of muscle (regulates calcium levels for muscle contraction) Sarcoplasm = Cytoplasm –To maintain ATP production during cellular respiration, contains high amounts of: mitochondria glycosomes that store sugar oxygen binding protein called myoglobin Sarcolemma = Plasma Membrane T tubules - The sarcolemma of muscle cells are not just on the outside, rather forms tubes that dive into the muscle cells Myosin and Actin= muscle proteins that create muscle cytoskeletal filaments for contraction

17 myofibril sarcolemma T-tubule Sarcoplasmic Reticulum Myosin (red) and Actin (blue)

18 Microstructures Each muscle fiber (muscle cell), is composed of many myofibrils. –Organized system of cytoskeleton filaments of actin and myosin proteins that do the actual contracting –Myofibrils are NOT CELLS –A sarcomere is one segment of a myofibril (muscle segments). –The series of sarcomeres produce the striated appearance of muscles

19 Muscle Fiber Sarcomere


21 Sarcomere organization Myofibril composed of repeating series of sarcomeres with dark A and light I bands. I bands intersected by Z discs mark the outer edges of each sarcomere. Contraction happens within one sarcomere.

22 Sarcomere Banding Pattern

23 Let’s sketch the sarcomere together and discuss the sliding filament model of muscle contraction How do muscle contract?

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