1. SBS Data & Image Analysis Special Interest Group April 9, 2008 St. Louis, Missouri Chair:Kurt Scudder, Accelrys, Inc. Co-Chairs:Susanne Heynen-Genel, Burnham Institute for Medical Research Mark Collins, ThermoFisher

2. Recap from 2007 D&IA SIG Meeting: Standards for HCS Data Interchange Goals from last year’s meeting: Form committee to develop standards Publish/distribute draft Minimum Information Standard presented by Mark Collins, Cellomics (ThermoFisher) Collect input from HCS user community, refine standard Present proposed standard at 2008 DIA SIG meeting

3. The ISAC (Re)Connection ISAC has active Data Standards Task Force – Extensive experience with standards formulation – Have NIH grant to fund standards development Current effort underway to extend FCS (flow-only standard) to more generalized “Analytical Cytometry Standard” (ACS) – Encompass imaging cytometry – Actively interested in input from HCS community

4. The Obvious Synergy Experience with image-based assays Experience with standards development

5. Proposed Path ISAC Draft Requirements for ACS ISAC Standards Development Expertise Cellomics Draft HCS Standard Requirements Document for HCS Data Interchange HCS Data Interchange Standard (possibly part of larger Analytical Cytomerty Standard) Input from other SBS standards efforts

6. Moving Forward ISAC leadership has given verbal commitment to support this collaboration on standards to the SBS leadership Resurrect group formed from last DIA SIG meeting, add new interested parties Adapt ISAC Requirements Document for HCS, publish to user community Get buy-in from end-users, instrument providers, and software vendors

7. SBS D&IA SIG Resources Co-Chairs: – Ilya Ravkin (ilya@ravkin.net)ilya@ravkin.net – Kurt Scudder (kscudder@accelrys.com)kscudder@accelrys.com Website: – http://www.ravkin.net/SBS/D&IA_SIG.htm