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Introduction to New High Power High Dose Class IV Laser Therapy.

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Presentation on theme: "Introduction to New High Power High Dose Class IV Laser Therapy."— Presentation transcript:

1 Introduction to New High Power High Dose Class IV Laser Therapy

2 HPLT was first introduced to the medical field in 2002 by then CEO of Avicenna Laser Technology, Inc, Bruce R. Coren, DVM, MS. The company invented and developed the first High Power Therapeutic Laser to receive FDA clearance in 2003.

3 Technological Medical Advancements is a spin off from Avicenna and was founded not only to advance the field of Laser Medicine but also to bring other innovative medical devices to the market place.TMA – Technological Medical Advancements is a spin off from Avicenna and was founded not only to advance the field of Laser Medicine but also to bring other innovative medical devices to the market place. TMA offers the most powerful laser platforms in the world and thus allowing physician's of all medical disciplines the capability to heal injuries previously refractive to traditional medical care.TMA offers the most powerful laser platforms in the world and thus allowing physician's of all medical disciplines the capability to heal injuries previously refractive to traditional medical care.

4 The TMA laser was designed from the ground up to be a therapeutic medical laser.

5 It was developed using research by our own biomedical engineers and clinicians as well as collaboration with a major medical school and university optics department.

6 We investigated important criteria such as wavelength, power and power density, optics and beam delivery in order to afford the greatest penetration and delivery of a therapeutic dose capable of stimulating tissue healing in deep seated pathologies.

7 Light Light Amplification by Amplification by Stimulated Stimulated Emission of Emission of Radiation Radiation

8 It could well stand for – Latest Advance For Surgeon to Enhance Revenue

9 Are used to cut, coagulate, and evaporate tissues. This type of laser replaces the scalpel blade.

10 The TMA Laser is the only laser available on the market that was designed to accomplish both surgical and therapeutic procedures.

11 Therapeutic Lasers are used for the stimulation of cell function. The biological effect is photochemical not thermal, as is the case with surgical lasers.

12 Surgical lasers collimate high amounts of laser energy into a beam of high intensity resulting in tissue destruction

13 High Power Therapeutic Lasers take a high amount of laser energy but instead of beam collimation you get beam divergence resulting in tissue stimulation

14 Veterinarians - Equine and Small Animal Human - Physical Medicine and Rehab - Pain Management - Orthopedists, Neurologists, - Family Practice

15 Chiropractors and Physical Therapists Podiatrists, Naturopaths and DOM’s MLB, NBA, NFL College Sports Teams Medical and Veterinary Colleges United States Military VA Hospitals

16 Laser therapy aims to bio-stimulate injured and dysfunctional tissues. Clinical studies and trials of Class III & IV laser technology indicate the following beneficial effects of light therapy on tissues and cells.

17 Chromophores are components of molecules which absorb light.

18 The stimulation of chromophores on mitochondrial membranes incites the production of ATP. Leading to a biological cascade of events.

19 Increased Growth factor response within cells and tissue as a result of increased ATP and protein synthesis. Accelerated cell reproduction and growth leading to faster repair of damaged tissues.

20 Increased metabolic activity- via increase in enzyme outputs, oxygen and nutrient availability. Stem cell activation

21 Faster Wound Healing - Laser significantly increases fibroblast and collagen production which are essential for tissue repair. Improved Vascular Activity - Increased capillary production leads to faster wound closure..

22 Greater Tensile Strength - Surgical repaired wounds heal with greater tensile strength, including skin, tendon, ligament and fascia. Scar Tissue Reduction - Wounds heal with less scar tissue formation.



25 Strengthening the immune system response via increasing levels of lymphocyte activity and through a newly researched mechanism termed photo-modulation of blood.

26 Stabilization of cellular membrane Lubart R, Friedman H, and Lavie R. Photobiostimulation as a function of different wavelengths. The Journal of Laser Therapy. Vol 12. World Association of Laser Therapy Karu T. et al. Changes in absorbance on monolayer of living cells induced by laser irradiation. IEEE Journal of Selected Topics in Quantum Electronics. IEEE Lasers and Electro-Optical Society. December (6):982. De Castro E Silva Jr. O, et al. Laser enhancement in hepatic regeneration for partially hepatectomized rats. Lasers in Surgery and Medicine (1):73-77

27 Acceleration of leukocytic activity Increased Prostaglandin synthesis Reduction in Interleukin 1(IL-1). Enhanced lymphocyte response Increased angiogenesis Temperature modulation

28 Laser Therapy Cytochrome ActivationRos Production Cell Membrane Changes Proton Gradient Change Ca, Na, K Ion Changes ATP IncreaseVasodilationPG SynthesisIL-1 Decrease Increased Leukocyte Activity Enhanced Lymphocyte Response Temperature Modulation AngiogenesisSOD Production

29 Accelerated Tissue Repair Accelerated Cell Growth Faster wound Healing Reduced Scar Tissue Formation Anti-Inflammation Anti-Pain (Analgesia)

30 Improved Vascular Activity Increased Metabolic Activity Improved Nerve Function Immunoregulation Trigger Point Resolution Acupuncture Pt. Stimulation

31 Improved Vascular Activity Increased Metabolic Activity Improved Nerve Function Immunoregulation Trigger Point Resolution Acupuncture Pt. Stimulation

32 Decreased inflammation of disc, nerve roots and the cauda equine Increase microcirculation of spinal structures Accelerate healing of annular defects Decreased formation of abnormal/non functional scar tissue

33 Decreased scar tissue and non-osseous hypertrophic changes Reduce pain associated with PRP – prolotherapy injection Decrease or even eliminate need for epidurals

34 Decreased inflammation of nerve tissue Accelerated Reinervation of nerve fibers Increase blood flow and microcirculation of tissue structures

35 Accelerate healing of open wounds Decreased formation of abnormal non- functional scar tissue Increase synovial fluid and cartilage production

36 Increase collagen and fibroblast production Increase osteoblastic activity and fracture healing Decreased bony edema – osteochondral bone bruise

37 Safety Training begins with YOU! Class IV Laser Beams can cause damage to the eyes Safety Glasses must be worn by everyone in the treatment area AKA Nominal Hazard Zone (NHZ)

38 Safety protocols must ensure sufficient precautions are taken to protect the health and safety of employees and patients. Use of safety goggles to prevent retinal exposure is paramount.

39 Laser safety eyewear is not a primary mode of protection They do not replace proper laser safety education, training, and careful clinical practice.

40 Fluorescein angiography of retina after laser irradiation Lesion

41 Training Equipment Purchase, Service, Quality Assurance Room Design Protective Equipment / Optical

42 Hazards Routine Procedures Administrative Controls/Management Electrical Hazards

43 Medical Instruments (Reflex Hammers, Stethoscope) Jewelry (Rings, Watches, Earrings) Treatment Table Mirrors, Door Knobs and other Fixtures




47 Reflect Absorb Transmit Scatter


49 Class 1 Lasers Laser Printers Compact Disc Players

50 Class 2 Lasers

51 Class 3a Lasers Office Depot Laser Pointers

52 Class 3b Lasers LLLT

53 Class 4 Lasers Surgical LasersTherapeutic Lasers

54 Pregnant Females Epiphyseal Lines In Children Pacemaker Thyroid, Gonads, & Testicles Light Sensitive Medications Corticosteroids Intolerance Eyes Carcinoma Hemorrhage Immuno-Suppressant Drugs Sympathetic Ganglia, The Vagus Nerves & Cardiac Region In Patients With Heart Disease

55 Although all therapeutic lasers bio- stimulate tissue, that is where the similarities end. Laser Therapy is all about Physics!

56 Therapy lasers are classified based on their power output Class IIIa = lasers 1 to 5mw of power (laser pointers) Class IIIb = lasers 6 to 500mw in power

57 Class IV = lasers above 500mw of power TMA Laser Platforms = 1,000 – 60,000 mw maximum continuous wave output

58 What we would like to do is find a volunteer with knee pain to demonstrate the efficacy of high dose laser therapy While we finish the lecture we will treat the patient and have him/her give you feed back as to how the pain level and range of motion have changed.

59 Laser Therapy 101 Rule #1: You Cannot Treat a Target That You Cannot Reach.

60 X-Ray Physics = Laser Physics Rule # 2

61 Laser Therapy 101 Rule #3: Overstimulation With Laser Energy Only Exists in a Petrie Dish

62 Laser Therapy 101 Rule #4: Understimulation and Lack of Penetration are the #1 Reasons for Poor Clinical Outcomes!

63 The therapeutic dosage of laser energy is measured in Joules Dosage is a function of the lasers power output For every one watt of continuous laser power output, one joule of laser energy is delivered per second of time

64 For a pulsed laser the energy delivery depends on the duty cycle. Duty cycle tells us what percentage of time the laser is on or actively firing. If the duty cycle is 50% then the laser at 1 watt only delivers 0.5 Joules / Second. For any given time period a continuous wave laser delivers twice as much energy than laser with a 50% duty cycle

65 The shorter the wavelength, the more readily the energy is absorbed in the body. The higher the wavelength, the deeper the penetration of photon energy.

66 980 nm: Low melanin, low water, low hemoglobin absorption thus an optimal wavelength to choose when designing a therapy laser for stimulating tissue at greater depths of penetration.


68 65% of laser energy is absorbed in the skin and subcutaneous tissue layers with the following having a high affinity for absorption: Hemoglobin in blood Melanin in skin, hair, moles, etc. Water (present in all biological tissue)

69 As light energy hits the surface of the skin and subsequent deeper layers, some of it is scattered and some of it is absorbed and some is reflected At each tissue interface less energy is available to pass further through to the next layer because of the effects of absorption, reflectance and transmission

70 Laser Energy is just another form of energy on the electromagnetic spectrum. Depth of penetration is determined by wavelength and energy density. Just like with x-rays when deeper penetration is required, more energy must be delivered to reach the target tissues.

71 Prime Determinants of Laser Penetration and Concomitant Tissue Stimulation are: Power – measured in Watts or milliwatts

72 Wavelength – measured in nanometers Power Density – measured in mw / cm2 Frequency – continuous wave versus pulsing

73 Since approximately 65% of the energy delivered is lost in the epidermis If you don’t start with enough energy on the skin, there will not be enough to stimulate cell healing in deeper tissues

74 If you do not have sustained power density over a long enough period of time treatments may be ineffective

75 A laser with two or more wavelengths only has the ability to penetrate as deep as each individual wavelengths allows Most class iv lasers that pulse or have a high duty cycle coupled with multiple wavelengths of energy emission will not penetrate as deep as CW lasers of a single wavelength or lasers that can pulse but still maintain a high average power output

76 Continuous wave lasers = 100% duty cycle, laser is always delivering energy which is needed to overcome absorption in the superficial layers Newer generation of TMA lasers can now pulse yet still maintain a high average power output allowing for greater tissue saturation with less thermal effects

77 Dual wavelength lasers only penetrate as deep as each wavelength individually. Penetration is not additive. There is no validated clinical benefit to this scenario. It is more of a marketing

78 For purposes of penetration it is more advantageous to have one wavelength of greater power that stimulates cell metabolism and tissue regeneration at all tissues densities in its pathway

79 Throughout our 13 years of clinical experience using a 980nm treatment beam, we have experienced stellar results with both superficial and deep pathologies. We still feel once you are treating within the infrared spectrum, power, power density and dosage are the key to better clinical outcomes.

80 In order to achieve penetration one must create significant energy density to overcome absorption in the superficial layers of the skin. With low power or pulsed lasers it is like pouring small amounts of water onto a large sponge (the dermis and subcutaneous tissues) and expecting the water to leak through.

81 In order to do so you must saturate the superficial layers of the sponge- with enough water-energy to soak the sponge-superficial tissue structures So as you pour more water-energy over the sponge it will start to penetrate or leak through.

82 This it what is needed to penetrate and why it is important to deliver a high amount of laser energy/dosage on the skin Especially if you want to reach deep seated pathologies.

83 49-73 mw/cm 2 for cell stimulation 1 EFFECTS OF INFRARED LASER EXPOSURE IN A CELLULAR MODEL OF WOUND HEALING Mark D. Skopin and Scott C. Molitor, Department of Bioengineering, University of Toledo, Toledo OH This study shows an optimal wavelength (980 nm) and power density range for wound healing and tissue stimulation

84 Tissue LayerMax Power (mw/cm2) Epidermis206 Dermis Layer182 Dermis Plexus Super.135 2nd Dermis Layer115 Dermis Plexus Prof.93 Muscle Tissue9.7 Power Setting 5 Watts, 3.0cm spot size, 980nm This is a snapshot in time. Calculated using computer models by U of Toledo.

85 Translation – As laser light or energy penetrates through the body more and more energy is absorbed so by the time you start reaching deeper structures there is not enough therapeutic energy to cause adequate tissue stimulation Thus the reason why low power lasers as well as pulsing lasers cannot effectively treat deep seated pathologies.

86 Duty Cycle – 100% Laser is firing continuously Duty Cycle – 50% Laser is firing 50% of the time. This will not only cut energy delivery but it will also affect ability to penetrate.

87 Pulsing – Lasers that pulse also do not emit continuous energy Lasers that can operate at 100% continuous wave output or pulse the laser energy while still maintaining a high average power output is key to treating deep seated pathologies and better clinical outcomes.

88 With a high power output the laser beam can easily penetrate deeper joints especially when compared to a class iii laser which at best only offers superficial penetration.

89 Under penetration - The typical low level or cold laser or weak or pulsed class iv laser does not concentrate the laser energy sufficiently to allow for adequate penetration

90 Under-dosage – The typical low level or cold laser or weak or pulsed class iv laser does not deliver enough energy to adequately stimulate deep seated inflammatory conditions

91 TMA protocols are successful because they call for delivery of significantly larger amounts of therapeutic energy than industry standard protocols.

92 TMA’s goal has always been to build the most efficacious laser available to deliver the best outcomes. Our lasers are built from the ground up and are designed to get patients who have failed traditional therapy better

93 Many other lasers are built based on economic factors or from taking laser from other markets like dentistry and converting them into weak class iv lasers There are no shortcuts to treating deep seated pathologies and one must deliver the correct dosage of laser energy in order to get the best outcomes.

94 Higher the power output of laser energy The Greater The Penetration and Dosage The Faster the Therapeutic Outcome

95 The Quicker the Patient Returns to Normal This is the main reasons we keep advancing our technology and developing more powerful lasers.

96 More power equates to deeper penetration, faster delivery of the proper therapeutic dosage, and ultimately better outcomes A 30 watt laser will not only penetrate deeper, it will put more therapeutic energy to the target pathology It will do this 3X faster than a 10 watt laser and 5X faster than a 12 watt laser with a duty cycle of 50%

97 Small Joint – lb. Pet = 6,000 Joules Small Joint – lb. Pet = 9,000 Joules Large Joint lb. Pet = 9,000 Joules

98 Large Joint lb. Pet 12-15,000 Joules Equine Dosages are typically Double the Small Animal Dosage for Large Joints Even more for back pathologies

99 The effects of HPLT can easily be documented Clinician’s can measure results using outcome assessment tools: Pressure Algometer Inclinometer, Goniometer Thermal Imaging and Doppler Studies VAS, PDQ – Pain Disability Questionnaire


101 LASER BRAND (In watts) MDO(1) DUTY CYCLE (2) MPTD(3) JPM(4) CPW(5) WARRANTY TMA - Diowave w 3600 $834 3 yr TMA - Diowave w 1800 $1,167 3 yr TMA - Diowave w 900 $1,600 3 yr TMA - Diowave w 600 $1,500 3 yr Litecure w 900 $1,800 2 yr Litecure w 600 $1,750 2 yr Klaser w 360 $3,667 2 yr Klaser cube w 450 $3,600 2 yr Cutting Edge <1.0 w 45 $20,000 not published Cutting Edge <1.0 w 105 $15,000 not published Class iii lasers 0.75 variable 0.75w , , yr

102 1.MDO = Maximum Diode Output 2.Duty Cycle = Average Time Diodes Are Firing 3.MPTD = Maximum Penetrating Therapeutic Dosage.

103 4. JPM = Joules Per Minute 5. CPW = Cost Per Watt (Continuous Power Output) Because wavelength and power determine penetration, and each wavelength penetrates independently, the maximum penetrating dose is no greater than the maximum power output of each diode. With a 50% duty cycle penetration of each diode gets cut in half.

104 Maximum power output per wavelength is one of the most important factors in favorable treatment outcome. With a dual wavelength laser, laser beam penetration is reduced by 50%; with a 50% duty cycle setting and dual wavelengths, laser penetration is equal ¼ of the stated power output of the laser.

105 With multiple-wavelength lasers (2-3) beam penetration is reduced even more significantly. If a 50% duty cycle setting is paired with a three-wavelength laser, beam penetration is equal to 1/6 of the stated laser power output. A 10W CW Diowave laser has a stronger maximum diode power output of any therapy laser currently produced.

106 Profound anti-inflammatory and analgesic effects Pain relief typically immediate Non-invasive and no side effects Profound tissue regeneration of all tissue types Overall contraindications minimal

107 The effects of HPLT can easily be documented Clinician’s can measure results using outcome assessment tools: Pressure Algometer Inclinometer, Goniometer Thermal Imaging and Doppler Studies VAS, PDQ – Pain Disability Questionnaire These tools are vital to document outcomes which ultimately lead to adequate reimbursement

108 Disc Pathologies, Spinal Stenosis, Radicular Pain, spondylolesthesis, and sacroiliac dysfunction Failed surgical back syndrome Accelerated Post Surgical, Soft and hard Tissue healing Arthritis (Degenerative Joint Disease) Foot Pain and Neuropathies Muscle, Ligament and Tendon Injuries Ulcerations and Open Wounds

109 Single wavelength laser True CW (Continuous Wave). Laser will operate all day on CW without issues Highest CW Power

110 A technological advancement in energy output and delivery The TMA suite of laser platforms offer the world’s most powerful and advanced therapeutic laser system ranging in power output from 10 – 60 watts or 10,000mw -60,000mw. As a veterinary based company we have treated or will know how to treat any condition you are confronted with, the ultimate result being a better outcome With the superior training and clinical support we provide veterinarians, the above goal will readily be achieved

111 Watt Laser Platform and 60 Watt Laser Platform

112 Laser Therapy is by far the most exciting new clinical treatment to advance veterinary medicine in the 21 st century It can also become one of your most significant profit centers in your practice All that’s need to be done to accomplish is to follow the Diowave Turnkey marketing plan that comes with every laser purchase For further information on bringing the a Diowave Laser into your practice you will find our contact information in the next page

113 In summary my recommendation is to bye the most powerful single continuous wavelength therapy laser you can afford over the next 5 years watts for SA watts for Equine or Mixed

114 10-15 Watt Laser Platform and 60 Watt Laser Platform

115 – Phone –


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