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HCL Patient Seminar September 2014 Quality of Life Monica Else.

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Presentation on theme: "HCL Patient Seminar September 2014 Quality of Life Monica Else."— Presentation transcript:

1 HCL Patient Seminar September 2014 Quality of Life Monica Else

2 Quality of life in chronic lymphocytic leukaemia Large trial of 777 patients from 136 centres in Argentina, Croatia, Greece, Ireland, Italy, New Zealand, Russia, UK Comparing 3 different treatments Self-assessed quality of life questionnaire 5-year follow-up

3 Quality of life in chronic lymphocytic leukaemia – results Else et al, Leuk Lymphoma, 53: ; 2012 The coloured boxes denote a statistically significant difference between groups (10 points or more, p<0.01)

4 Quality of life in leukaemia: the long term

5 What are the implications for HCL?

6 Duration of remission in HCL Dearden et al, Leuk Lymphoma, 52(S2): 21-24; 2011

7 How do you make sure you have a CR? Bone marrow biopsy Further treatment if only a PR

8 Conclusions Having severe symptoms at the outset does not predict poor quality of life in the longer term Disease progression and relapse are associated with poor quality of life Long-term remission equates with good quality of life (“getting your life back”) and should be the aim of therapy


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