Presentation on theme: "Why Are We Still Doing Industrial Age Drug Discovery For Neglected Diseases in The Information Age? Sean Ekins Collaborations In Chemistry, Fuquay Varina,"— Presentation transcript:
Why Are We Still Doing Industrial Age Drug Discovery For Neglected Diseases in The Information Age? Sean Ekins Collaborations In Chemistry, Fuquay Varina, NC
But Drug Discovery has not changed much in 40 years
Because change happens slowly Drug discovery is a very slow race… that needs a kickstart
And of course no treatments for neglected diseases are blockbusters Still valuing the 70’s BLOCKBUSTER model but its changing Produce few of …
The Old School vs New School screening New School - Many hurdles before in vivo - lots of data Yet HTS started in the 1980’s!! Old school – go in vivo at outset – little data New database technologies work well for New school but..Old School type data ?
Drug Discovery Archeology Still a heavy emphasis on “testing” “doing “ rather than ‘learning’ Mining data and historic data will increase in value Data becomes a repurposing opportunity How do we position databases for this? What about neglected diseases?