Presentation on theme: "Pedigree What do you think of when you read the above word? –Dog food –Family –Lineage –inheritance."— Presentation transcript:
Pedigree What do you think of when you read the above word? –Dog food –Family –Lineage –inheritance
Pedigree Chart that shows how a trait and the genes that control it are inherited in a family.
Pedigree -Females are circles -Males are squares -Shading is an individual with the trait -Individual carrying the trait
Pedigree Marriage / mating Offspring (in order of birth) Sex unknown 1 2 3 4
Finding a Gene on the Chromosome Map »We can examine inheritance in a family by constructing a pedigree. »In this family certain members (in black) have Whirling disorder.
Finding a Gene on the Chromosome Map How do scientists find the genes responsible for a hereditary disease in a family? »Think of all the genes in a person’s genome as puzzle pieces in a jigsaw puzzle. »Each piece represents a different gene. »Because all humans have the same set of genes in the same order, every family member has the same basic jigsaw puzzle arrangement.
Finding a Gene on the Chromosome Map How do scientists find the genes responsible for a hereditary disease in a family? »Genes are passed from parent to child. »Different colors represent different alleles (forms) of a gene.
Finding a Gene on the Chromosome Map Examine the following pedigree and the corresponding jigsaw puzzle genomes of the family members. (Scientists would be examining the pattern of bands left by each person’s DNA in a gel.) Use the process of elimination to find the gene for Whirling disorder. (First person to identify the gene using the numbered guide, yell GENE!)
Make a pedigree based on the following passage about freckles. 1.Although Jane and Joe Smith have dimples, their daughter, Clarissa, does not. Joe’s dad has dimples, but his mother and his sister, Grace, do not. Jane’s dad, Mr. Renaldo, her brother, Jorge, and her sister, Emily, do not have dimples, but her mother does.
Clarisa Emily Jorge JaneJoe Grace Mrs Renaldo Mr. Renaldo Mrs. Smith Mr. Smith
Andy, Penny, and Delbert have freckles, but their mother, Mrs. Cummins, does not. Mrs. Biodano, Mrs. Cummins’s sister, has freckles, but her parents, Mr. And Mrs. Lutz, do not. Deidra and Darlene Giordano are freckled, but their sister, Dixie, like her father, is not freckled.