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Utility of Intraoperative Frozen Section Histopathology in the Diagnosis of Periprosthetic Joint Infection by Geoffrey Tsaras, Awele Maduka-Ezeh, Carrie.

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Presentation on theme: "Utility of Intraoperative Frozen Section Histopathology in the Diagnosis of Periprosthetic Joint Infection by Geoffrey Tsaras, Awele Maduka-Ezeh, Carrie."— Presentation transcript:

1 Utility of Intraoperative Frozen Section Histopathology in the Diagnosis of Periprosthetic Joint Infection by Geoffrey Tsaras, Awele Maduka-Ezeh, Carrie Y. Inwards, Tad Mabry, Patricia J. Erwin, M. Hassan Murad, Victor M. Montori, Colin P. West, Douglas R. Osmon, and Elie F. Berbari J Bone Joint Surg Am Volume 94(18):1700-1711 September 19, 2012 ©2012 by The Journal of Bone and Joint Surgery, Inc.

2 Flow chart illustrating study selection. Geoffrey Tsaras et al. J Bone Joint Surg Am 2012;94:1700- 1711 ©2012 by The Journal of Bone and Joint Surgery, Inc.

3 Forest plot of the diagnostic odds ratio (OR) of frozen section histopathology for the diagnosis of periprosthetic joint infection. Geoffrey Tsaras et al. J Bone Joint Surg Am 2012;94:1700- 1711 ©2012 by The Journal of Bone and Joint Surgery, Inc.

4 Forest plot of the likelihood ratio (LR) of a positive frozen section result for the diagnosis of periprosthetic joint infection. Geoffrey Tsaras et al. J Bone Joint Surg Am 2012;94:1700- 1711 ©2012 by The Journal of Bone and Joint Surgery, Inc.

5 Forest plot of the likelihood ratio (LR) of a negative frozen section result for the exclusion of periprosthetic joint infection. Geoffrey Tsaras et al. J Bone Joint Surg Am 2012;94:1700- 1711 ©2012 by The Journal of Bone and Joint Surgery, Inc.

6 Forest plot of the likelihood ratio (LR) of a positive frozen section result using a threshold of 5 polymorphonuclear leukocytes per high-power field for the diagnosis of periprosthetic joint infection. Geoffrey Tsaras et al. J Bone Joint Surg Am 2012;94:1700- 1711 ©2012 by The Journal of Bone and Joint Surgery, Inc.

7 Forest plot of the likelihood ratio (LR) of a negative frozen section result using a threshold of 5 polymorphonuclear leukocytes per high-power field for the exclusion of periprosthetic joint infection. Geoffrey Tsaras et al. J Bone Joint Surg Am 2012;94:1700- 1711 ©2012 by The Journal of Bone and Joint Surgery, Inc.

8 Fagan nomogram for calculating the post-test probability of periprosthetic joint infection. Geoffrey Tsaras et al. J Bone Joint Surg Am 2012;94:1700- 1711 ©2012 by The Journal of Bone and Joint Surgery, Inc.

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