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Internal milieu BloodLymph Interstitial fluid. Internal milieu is the EXTRA CELLULAR FLUID ENVIRONMENT. Internal milieu is the EXTRA CELLULAR FLUID ENVIRONMENT.

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Presentation on theme: "Internal milieu BloodLymph Interstitial fluid. Internal milieu is the EXTRA CELLULAR FLUID ENVIRONMENT. Internal milieu is the EXTRA CELLULAR FLUID ENVIRONMENT."— Presentation transcript:

1 Internal milieu BloodLymph Interstitial fluid

2 Internal milieu is the EXTRA CELLULAR FLUID ENVIRONMENT. Internal milieu is the EXTRA CELLULAR FLUID ENVIRONMENT. 1. Blood 2. Lymph 3. Interstitial fluid (Claude Bernard and Charles Robin)

3 Blood - fluid of the circulatory system. Blood - fluid of the circulatory system. Lymph - fluid of the lymphatic system. Lymph - fluid of the lymphatic system. Interstitial – fluid which surrounds ALL our CELLS (including the vessels). Interstitial – fluid which surrounds ALL our CELLS (including the vessels).

4 Blood – 1 of the 3 components of the circulatory system. This system distributes nourrishment/oxygen. It also drives out waste that our body does not need Blood – 1 of the 3 components of the circulatory system. This system distributes nourrishment/oxygen. It also drives out waste that our body does not need

5 The circulatory system is composed of heart – vessels – blood.

6 The heart is composed of: Two atriums (two cavities at the top) Two ventricles (two cavities at the bottom)

7 The circulatory system has 2 circuits: The circulatory system has 2 circuits: Pulmonary circulation: heart – lungs - heart. Pulmonary circulation: heart – lungs - heart. Systemic circulation: heart - whole body - heart. Systemic circulation: heart - whole body - heart.

8 Pulmonary circulation: takes blood which is poor in oxygen from the left ventricle to the lungs and brings that blood back to the right atrium. Pulmonary circulation: takes blood which is poor in oxygen from the left ventricle to the lungs and brings that blood back to the right atrium.

9 Systemic circulation: takes oxygenated blood which from right ventricle to the lungs and brings that blood back to the left atrium. Systemic circulation: takes oxygenated blood which from right ventricle to the lungs and brings that blood back to the left atrium.

10 The double circulatory system distributes what we need to all our cells. To do so, it needs the help of the interstitial fluid. The interstitial fluid is the liquid surrounding our cells. The double circulatory system distributes what we need to all our cells. To do so, it needs the help of the interstitial fluid. The interstitial fluid is the liquid surrounding our cells.

11 1. Vessels don’t reach all cells of the body. To distribute to all cells what our body needs, the space among the cells is filled up with a liquid, which is called interstitial fluid.

12 What is the internal milieu? The circulatory and the respiratory system. The circulatory and the respiratory system. The digestive system. The digestive system. The fluids which transport to our body what we need and drive out the waste. The fluids which transport to our body what we need and drive out the waste. All the answers are true. All the answers are true.

13 What does the interstitial fluid do? Distribute nourishment to the cells of our body that are far from the circulatory system. Distribute nourishment to the cells of our body that are far from the circulatory system. Distribute nourishment to all the cells of the body. Distribute nourishment to all the cells of the body. Help eliminate from our body what we don’t need. Help eliminate from our body what we don’t need. Second and third answers are correct. Second and third answers are correct.

14 Which are the components of the circulatory system? Blood, vessels, lymph and heart. Blood, vessels, lymph and heart. Blood, vessels, nodles and heart. Blood, vessels, nodles and heart. Heart, lymph, interstitial fluid and blood. Heart, lymph, interstitial fluid and blood. Heart, vessels and blood. Heart, vessels and blood.

15 Which of the following is true The pulmonary system takes oxygenated blood from the left ventricle to the lungs. The pulmonary system takes oxygenated blood from the left ventricle to the lungs. The systemic system takes oxigenated blood from the right ventricle to the lungs. The systemic system takes oxigenated blood from the right ventricle to the lungs. The lungs send oxygenated blood to the right atrium. The lungs send oxygenated blood to the right atrium. Second and third answers are true. Second and third answers are true.

16 Interstitial fluid - This liquid is basically made of water, salt, sugar, hormones, neurotransmitters, carbon dioxide and fatty acids. Its composition is very similar to plasma… Interstitial fluid - This liquid is basically made of water, salt, sugar, hormones, neurotransmitters, carbon dioxide and fatty acids. Its composition is very similar to plasma…

17 1. The substances that our body needs (oxygen and nourrishment) pass from the vessels to the interstitial fluid through the SYSTOLIC pressure (the pressure coming from heart).

18 At the same time, the substances that our body DOESN’T need and has to eliminate pass from the interstitial fluid to some capillaries which are called lymph capillaries. At the same time, the substances that our body DOESN’T need and has to eliminate pass from the interstitial fluid to some capillaries which are called lymph capillaries.

19 What is the interstitial fluid made of? Blood and water. Blood and water. Water, salt, sugar, hormones, neurotransmitters, carbon dioxide and fatty acids. Water, salt, sugar, hormones, neurotransmitters, carbon dioxide and fatty acids. Only plasma and fatty acids. Only plasma and fatty acids. Only plasma and hormones. Only plasma and hormones.

20 What is the interstitial space? The space among cells The space among cells The space containing interstitial fluid The space containing interstitial fluid The tissue space The tissue space All the answers are correct. All the answers are correct.

21 How do required substances get into our vessels? Through the osmotic pressure Through the osmotic pressure Through the systolic pressure Through the systolic pressure First and second answers are true First and second answers are true None of the previous answers is true. None of the previous answers is true.

22 What is the systolic pressure? The pressure pushed by the heart into the interstitial fluid The pressure pushed by the heart into the interstitial fluid The pressure pulled by the heart from the interstitial fluid The pressure pulled by the heart from the interstitial fluid The pressure pushed out of the vessels by the different presence of water between interstitial fluid and the blood. The pressure pushed out of the vessels by the different presence of water between interstitial fluid and the blood. The pressure pulled into the vessels by the different presence of water between the interstitial fluid and the blood. The pressure pulled into the vessels by the different presence of water between the interstitial fluid and the blood.

23 Which are the vessels where the non needed substances are concentrated? Arteries Arteries Platelets Platelets Lymph capillaries Lymph capillaries White blood cells White blood cells

24 1. The substances that our body does not need pass to the lymphatic capillaries through the OSMOTIC pressure. Lymph vessels

25 This pressure is possible due to a different concentration of water in the interstitial fluid and in the blood. Basically, plasma and interstitial fluid are very similar, but interstitial fluid has a higher concentration of water. This pressure is possible due to a different concentration of water in the interstitial fluid and in the blood. Basically, plasma and interstitial fluid are very similar, but interstitial fluid has a higher concentration of water.

26 Vessels themselves are made of cells, very thin cells, which are called …. Vessels themselves are made of cells, very thin cells, which are called ….

27 What are vessels made of? They are made of cells They are made of cells They are made of tissue They are made of tissue They are made of red cells They are made of red cells First and second are true First and second are true

28 How can interstitial fluid squeeze into lymph capillaries? Due to a different concentration of water of blood and interstitial fluid Due to a different concentration of water of blood and interstitial fluid The heart pulls the interstitial fluid into the vessels. The heart pulls the interstitial fluid into the vessels. Both of them are true Both of them are true None of them is true None of them is true

29 Blood... Has a higher concentration of water than interstitial fluid Has a higher concentration of water than interstitial fluid Has a lower concentration of water than interstitial fluid Has a lower concentration of water than interstitial fluid Has the same concentration of water than the interstitial fluid Has the same concentration of water than the interstitial fluid None of them is true None of them is true

30 Vessels are divided into veins, arteries and capillaries. Vessels are divided into veins, arteries and capillaries.

31 1. Inside the vessels, there is plasma, red blood cells, white blood cells and platelets. When the blood coagulates, the plasma loses a part of its ingredients. This is the human serum.

32 Interstitial fluid is a solution that surrounds the cells of multicellular animals. It is found in all interstitial spaces, that is to say, in all the spaces among the cells. (tissue spaces) Interstitial fluid is a solution that surrounds the cells of multicellular animals. It is found in all interstitial spaces, that is to say, in all the spaces among the cells. (tissue spaces)

33 The interstitial fluid is composed of water, of course, but also of salt, sugar, hormones, neurotransmisors... The interstitial fluid is composed of water, of course, but also of salt, sugar, hormones, neurotransmisors...

34 On average, a person has about 11 litres of interstitial fluid BUT ONLY 5 LITERS OF BLOOD. The interstitial fluid provides alls the cells of the body with nourrishment and it is also a mean of wasting removal. It makes up 16% of the total body weight, whereas blood makes up 8% of the total body weight. On average, a person has about 11 litres of interstitial fluid BUT ONLY 5 LITERS OF BLOOD. The interstitial fluid provides alls the cells of the body with nourrishment and it is also a mean of wasting removal. It makes up 16% of the total body weight, whereas blood makes up 8% of the total body weight.

35 How many kinds of vessels are there in our body?

36 Arteries, veins and capillaries Arteries, veins and capillaries

37 What is blood composed of?

38 It is composed of plasma, red blood cells, white blood cells and platelets. It is composed of plasma, red blood cells, white blood cells and platelets.

39 What can we find inside the vessels?

40 Inside the vessels, there is plasma, red blood cells, white blood cells and platelets. Inside the vessels, there is plasma, red blood cells, white blood cells and platelets.

41 What happens when the blood coagulates?

42 When the blood coagulates, the plasma loses a part of its ingredients. The result is the human serum. When the blood coagulates, the plasma loses a part of its ingredients. The result is the human serum.

43 Plasma and interstitial fluid are very similar. Plasma is the major component of blood. Plasma and interstitial fluid are very similar. Plasma is the major component of blood. This similarity is due to a continuous exchange between plasma and interstitial fluid. This similarity is due to a continuous exchange between plasma and interstitial fluid.

44 In the vessels (blood vessels) there is a certain concentration of water, which is lower that outside the vessels. The reason for this less concentration of water inside the vessels is keeping the equilibrium. In the vessels (blood vessels) there is a certain concentration of water, which is lower that outside the vessels. The reason for this less concentration of water inside the vessels is keeping the equilibrium.

45 The heart (systolic force) generates a HYDROSTATIC pressure, which pushes the water OUT OF the vessels. The heart (systolic force) generates a HYDROSTATIC pressure, which pushes the water OUT OF the vessels. Small solutes have the ability of passing through the walls of the capillaries. This is called osmosis. The OSMOTIC pressure drives water back into the capillaries. Small solutes have the ability of passing through the walls of the capillaries. This is called osmosis. The OSMOTIC pressure drives water back into the capillaries.

46 Lymph is the fluid that is formed when the interstitial fluid is collected through capillaries (lymph capillaries). The interstitial fluid gets into the capillaries through the OSMOTIC pressure, that is to say, due to a different concentration of water in the interstitial fluid and in the blood. Lymph is the fluid that is formed when the interstitial fluid is collected through capillaries (lymph capillaries). The interstitial fluid gets into the capillaries through the OSMOTIC pressure, that is to say, due to a different concentration of water in the interstitial fluid and in the blood.

47 The lymph is transported through the lymph vessels into the lymph nodes. The lymph is transported through the lymph vessels into the lymph nodes.

48 When our body has a bacteria, lymph picks it up and brings it to lymph nodes, where it is destroyed. When our body has a bacteria, lymph picks it up and brings it to lymph nodes, where it is destroyed.

49 Blood is the fluid that circulates in the principal vascular system. It is composed of: Blood is the fluid that circulates in the principal vascular system. It is composed of: Plasma. Over ½ of blood is plasma (=water, salt and proteins) Plasma. Over ½ of blood is plasma (=water, salt and proteins) blood cells (red & white) blood cells (red & white) platelets platelets

50 Its main functions are: Its main functions are: Deliver oxygen to the muscles Deliver oxygen to the muscles Regulate the internal temperature (that is to say, remove heat) Regulate the internal temperature (that is to say, remove heat) Take away from the organism the lactic acid (balance) Take away from the organism the lactic acid (balance)

51 Plasma represents Almost 8% of human blood Almost 8% of human blood Almost 16% of human blood Almost 16% of human blood Almost 50% of human blood Almost 50% of human blood Almost 10% of human blood Almost 10% of human blood

52 Which of the following is true? Interstitial fluid is made of plasma. Interstitial fluid is made of plasma. Plasma is very different to interstitial fluid due to a continuous exchange between plasma and interstitial fluid Plasma is very different to interstitial fluid due to a continuous exchange between plasma and interstitial fluid Plasma is very similar to interstitial fluid. Plasma is very similar to interstitial fluid.

53 Approximately 8% of our body weight is made up of blood (whereas interstitial fluid means 16% of our weight). This means around 4-5 litres in a woman and 5-6 litres in a man. The slight difference is due to the size of the body, which is usually bigger in a man. Approximately 8% of our body weight is made up of blood (whereas interstitial fluid means 16% of our weight). This means around 4-5 litres in a woman and 5-6 litres in a man. The slight difference is due to the size of the body, which is usually bigger in a man.

54 Blood normal temperature is about 38ºC. Blood normal temperature is about 38ºC. Blood in the arteries has a brighter red, because it contains a higher concentration of oxygen. Blood in the arteries has a brighter red, because it contains a higher concentration of oxygen. It has not been found an artificial substitute of human blood yet. It has not been found an artificial substitute of human blood yet.

55 Blood normal temperature is about 38ºC. Blood normal temperature is about 38ºC. Blood in the arteries has a brighter red, because it contains a higher concentration of oxygen. Blood in the arteries has a brighter red, because it contains a higher concentration of oxygen.

56 It is the main ingredient of blood (approximately 55%). 5% of blood is composed of red cells. It is the main ingredient of blood (approximately 55%). 5% of blood is composed of red cells. When blood coagulates, some plasma ingredients disappear. The rest of it is the blood serum. When blood coagulates, some plasma ingredients disappear. The rest of it is the blood serum.

57 Which of the following is true? Approximately 8% of our body weight is made up of blood and 16% of our body weight is interstitial fluid. Approximately 8% of our body weight is made up of blood and 16% of our body weight is interstitial fluid. Approximately 16% of our body weight is made up of blood and 8% of our body weight is interstitial fluid Approximately 16% of our body weight is made up of blood and 8% of our body weight is interstitial fluid

58 How many litres of blood does our body have?

59 Around 4-5 litres in a woman and 5-6 litres in a man. The slight difference is due to the size of the body, which is usually bigger in a man. Around 4-5 litres in a woman and 5-6 litres in a man. The slight difference is due to the size of the body, which is usually bigger in a man.

60 What is the normal blood temperature?

61 Blood normal temperature is about 38ºC. Blood normal temperature is about 38ºC.

62 What are the main functions of blood?

63 Deliver oxygen to the muscles Deliver oxygen to the muscles Regulate the internal temperature (that is to say, remove heat) Regulate the internal temperature (that is to say, remove heat) Take away from the organism the lactic acid (balance) Take away from the organism the lactic acid (balance)

64 Red blood cells, also called erythrocytes, are the cells that deliver oxygen to the body tissues through the circulatory system. The red blood cells take up oxygen in the lungs and release it into tissues when they squeeze through body’s capilaries. Red blood cells, also called erythrocytes, are the cells that deliver oxygen to the body tissues through the circulatory system. The red blood cells take up oxygen in the lungs and release it into tissues when they squeeze through body’s capilaries. It is composed of: It is composed of: Hemoglobin Hemoglobin Iron Iron Oxygen (responsible for the red color of the cells) Oxygen (responsible for the red color of the cells)

65 How are red blood cells also called?

66 Red blood cells are also called erythrocytes Red blood cells are also called erythrocytes

67 What are red blood cells composed of?

68 Hemoglobin Hemoglobin Iron Iron Oxygen (responsible for the red color of the cells) Oxygen (responsible for the red color of the cells)

69 White blood cells are the cells of the immune system that protect the body against infectious diseases and foreign invaders. They are also called leukocytes or leucocytes and derived from a potent cell in the bone marrow. White blood cells are the cells of the immune system that protect the body against infectious diseases and foreign invaders. They are also called leukocytes or leucocytes and derived from a potent cell in the bone marrow.

70 Platelets are the cells which are responsible for the coagulation, that is to say, to stop bleeding. They also called "thrombocytes". They derived from the some cells of the bone marrow which are called megakaryocytes. Platelets are the cells which are responsible for the coagulation, that is to say, to stop bleeding. They also called "thrombocytes". They derived from the some cells of the bone marrow which are called megakaryocytes. megakaryocytes

71 What is the function of white blood cells?

72 What is the function of platelets?


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